IL-25/IL-33/TSLP应答轴在调节Th2型免疫应答和哮喘发生与转归过程中的作用研究

81471594
2014
H1106.超敏反应性疾病
孙英
面上项目
教授
首都医科大学
71万元
白细胞介素25;白细胞介素33;胸腺基质淋巴生成素;哮喘
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 IL-33诱导的小鼠过敏原非依赖性哮喘样模型肺组织免疫细胞及亚群的改变 期刊论文 袁琳洁;陈诗皓;安高;黄琼;易达委;李艳;吕喆;王晶晶;黄克武;王炜;孙英
2 Interleukin (IL)-25: Pleiotropic roles in asthma 期刊论文 Yao Xiujuan;Sun Yongchang;Wang Wei;Sun Ying
3 The effects of interleukin-33 on airways collagen deposition and matrix metalloproteinase expression in a murine surrogate of asthma 期刊论文 An Gao;Zhang Xin;Wang Wenjun;Huang Qiong;Li Yan;Shan Shan;Corrigan Chris J.;Wang Wei;Ying Sun
4 IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma model 期刊论文 Yao X;Wang W;Li Y;Huang P;Zhang Q;Wang J;Wang W;Lv Z;An Y;Qin J;Corrigan CJ;Huang K;Sun Y;Ying S
5 Distinct sustained structural and functional effects of interleukin-33 and interleukin-25 on the airways in a murine asthma surrogate 期刊论文 Li Y;Wang W;Huang P;Zhang Q;Yao X;Wang J;Lv Z;An Y;Corrigan CJ;Huang K;Ying S
6 IL-33通过活化巨噬细胞NF-κB信号通路参与低氧性肺动脉高压的发生发展 期刊论文 刘杰;沙宇惠;高阳;杜晓楠;王文俊;黄琼;孙英;王炜
7 Bronchial Allergen Challenge of Patients with Atopic Asthma Triggers an Alarmin (IL-33, TSLP, and IL-25) Response in the Airways Epithelium and Submucosa 期刊论文 Wang Wei;Li Yan;Lv Zhe;Chen Yan;Li Yun;Huang Kewu;Corrigan Chris J;Ying Sun
8 Comparison of Composition and Diversity of Bacterial Microbiome in Human Upper and Lower Respiratory Tract 期刊论文 Feng Zhi-Hong;Li Qin;Liu Si-Ran;Du Xiao-Nan;Wang Chen;Nie XH;Wang Wei;Ying Sun
9 Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling by the PI3K inhibitor LY294002 期刊论文 Huang Ping;Li Yan;Lv Ze;Wang Jingjing;Zhang Qian;Yao Xiujuan;Corrigan Chris J;Huang Kewu;Wang Wei;Ying Sun
10 Nasal administration of interleukin-33 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma surrogate 期刊论文 Shan S;Li Y;Wang J;Lv Z;Yi D;Huang Q;Corrigan CJ;Wang W;Quangeng Z;Ying S
11 Kinetics of the accumulation of group 2 innate lymphoid cells in IL-33-induced and IL-25-induced murine models of asthma: a potential role for the chemokine CXCL16 期刊论文 Li Yan;Chen Shihao;Chi Yafei;Yang Yiran;Chen Xiwen;Wang Huating;Lv Zhe;Wang Jingjing;Yuan Linjie;Huang Ping;Huang Kewu;Corrigan Chris J;Wang Wei;Ying Sun
12 IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1 alpha and VEGF Expression in Vascular Endothelial Cells 期刊论文 Liu Jie;Wang Wang;Wang Lei;Chen Shihao;Tian Bo;Huang Kewu;Corrigan Chris J.;Ying Sun;Wang Wei;Wang Chen
13 IL-37对粉尘螨诱导气道上皮及固有免疫细胞产生IL-6的作用研究 期刊论文 陈诗皓;杜晓楠;李艳;吕喆;秦啸峰;孙英;王炜
14 IL-17家族与哮喘 期刊论文 吕文漪;王炜;陈彦
15 Characteristics of Proinflammatory Cytokines and Chemokines in Airways of Asthmatics: Relationships with Disease Severity and Infiltration of Inflammatory Cells 期刊论文 Yang Ting;Li Yan;Lyu Zhe;Huang Kewu;Corrigan Chris J.;Ying Sun;Wang Wei;Wang Chen
16 上皮源性细胞因子IL-33、IL-25和TSLP在哮喘发病机制中的作用 期刊论文 张鑫;王炜;孙英
17 Elevated Expression of IL-33 and TSLP in the Airways of Human Asthmatics In Vivo: A Potential Biomarker of Severe Refractory Disease 期刊论文 Li Yan;Wang Wei;Lv Zhe;Li Yun;Chen Yan;Huang Kewu;Corrigan Chris J.;Ying Sun
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