典型环境污染物与超细颗粒低水平联合暴露的心血管毒性及机制研究

81230065
2012
H3007.卫生毒理
孙志伟
重点项目
教授
首都医科大学
280万元
典型环境污染物;机制;心血管毒性;超细颗粒;联合作用
2013-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Gene expression profiles and bioinformatics analysis of human umbilical vein endothelial cells exposed to PM2.5 期刊论文 Hejing Hu;Collins Otieno Asweto;Jing Wu;Yanfeng Shi;Lin Feng;Xiaozhe Yang;Shuang Liang;Lige Cao;Junchao Duan;Zhiwei Sun
2 Combined toxicity of amorphous silica nanoparticles and methylmercury to human lung epithelial cells 期刊论文 Yongbo Yu;Junchao Duan;Yang Li;Yang Yu;Minghua Jin;Chenxu Li;Yapei Wang;Zhiwei Sun
3 Combined toxicity of silica nanoparticles and methylmercury on cardiovascular system in zebrafish (Danio rerio) embryos 期刊论文 Junchao Duan;Hejing Hu;Qiuling Li;Lizhen Jiang;Yang Zou;Yapei Wang;Zhiwei Sun
4 Co-exposure to amorphous silica nanoparticles and benzo[a]pyrene at low level in human bronchial epithelial BEAS-2B cells 期刊论文 Jing Wu;Yanfeng Shi;Collins Asweto;Lin Feng;Xiaozhe Yang;Yannan Zhang;Hejing Hu;Junchao Duan;Zhiwei Sun
5 Fine particulate matter induces vascular endothelial activation via IL-6 dependent JAK1/STAT3 signaling pathway 期刊论文 Hejing Hu;Jing Wu;Qiuling Li;Collins Asweto;Lin Feng;Xiaozhe Yang;Fengkui Duan;Junchao Duan;Zhiwei Sun
6 1H NMR-Based Metabolomics Study on Repeat Dose Toxicity of Fine Particulate Matter in Rats after Intratracheal Instillation 期刊论文 Yannan Zhang;Hejing Hu;Yanfeng Shi;Xiaozhe Yang;Lige Cao;Jing Wu;Collins Otieno Asweto;Lin Feng;Junchao Duan;Zhiwei Sun
7 一种检测纳米材料心脏毒性的方法 专利 段军超;孙志伟;周显青;黄沛力;崔淑香
8 Silica nanoparticlesinduce autophagic activity, disturb endothelial cell homeostasis and impairangiogenesis 期刊论文 Junchao Duan;Yongbo Yu;Yang Yu;Yang Li;Peili Huang;Xianqing Zhou;Shuangqing Peng;Zhiwei Sun
9 Cardiovasculartoxicity evaluation of silica nanoparticles in endothelial cells and zebrafishmodel 期刊论文 Junchao Duan;Yongbo Yu;Yang Li;Yang Yu;Zhiwei Sun
10 Inflammatory response and blood hypercoagulable state induced by low level co-exposure with silica nanoparticles and benzo[a]pyrene in zebrafish (Danio rerio) embryos 期刊论文 Junchao Duan;Yang Yu;Yang Li;Yapei Wang;Zhiwei Sun
11 Genome-wide transcriptional analysis of cardiovascular-related genes and pathways induced by PM2.5 in human myocardial cells 期刊论文 Lin Feng;Xiaozhe Yang;Collins Otieno Asweto;Jing Wu;Yannan Zhang;Hejing Hu;Yanfeng Shi;Junchao Duan;Zhiwei Sun
12 Comprehensive understanding of PM2.5 on gene and microRNA expression patterns in zebrafish (Danio rerio) model 期刊论文 Junchao Duan;Yang Yu;Yang Li;Li Jing;Man Yang;Ji Wang;Yanbo Li;Xianqing Zhou;Mark R. Miller;Zhiwei Sun
13 Microarray-based bioinformatics analysis of the combined effects of SiNPs and PbAc on cardiovascular system in zebrafish 期刊论文 Hejing Hu;Yannan Zhang;Yanfeng Shi;Lin Feng;Junchao Duan;Zhiwei Sun
14 Multi-organ toxicity induced by fine particulate matter PM2.5 in zebrafish (Danio rerio) model 期刊论文 Junchao Duan;Hejing Hu;Yannan Zhang;Lin Feng;Yanfeng Shi;Mark R. Miller;Zhiwei Sun
15 Low-dose exposure of silica nanoparticles induces cardiac dysfunction via neutrophil-mediated inflammation and cardiac contraction in zebrafish embryos 期刊论文 Junchao Duan;Yang Yu;Yang Li;Yanbo Li;Hongcui Liu;Li Jing;Man Yang;Ji Wang;Chunqi Li;Zhiwei Sun
16 Silica nanoparticlesinduce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signalingpathway 期刊论文 Junchao Duan;Yongbo Yu;Yang Yu;Yang Li;Ji Wang;Weijia Geng;Lizhen Jiang;Qiuling Li;Xianqing Zhou;Zhiwei Sun
17 Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-kappaB signaling 期刊论文 Caixia Guo;Yinye Xia;Piye Niu;Lizhen Jiang;Junchao Duan;Yang Yu;Xianqing Zhou;Yanbo Li;Zhiwei Sun
18 Combined Effect of Silica Nanoparticles and Benzo[a]pyrene on Cell Cycle Arrest Induction and Apoptosis in Human Umbilical Vein Endothelial Cells 期刊论文 Collins Otieno Asweto;Jing Wu;Hejing Hu;Lin Feng;Xiaozhe Yang;Junchao Duan;Zhiwei Sun
19 Low-dose combined exposure of nanoparticles and heavy metal compared with PM2.5 in human myocardial AC16 cells 期刊论文 Lin Feng;Xiaozhe Yang;Collins Otieno Asweto;Jing Wu;Yannan Zhang;Hejing Hu;Yanfeng Shi;Junchao Duan;Zhiwei Sun
20 Silica nanoparticlesinduced the pre-thrombotic state in rats via activation of coagulation factorXII and JNK- NF-κB/AP-1 pathway 期刊论文 Lizhen Jiang;Yanbo Li;Yang Li;Caixia Guo;Yongbo Yu;Yang Zou;Yumei Yang;Yang Yu;Junchao Duan;Weijia Geng;Chunqi Li;Zhiwei Sun
21 Comprehensive gene and microRNA expression profiling on cardiovascular system in zebrafish co-exposured of SiNPs and MeHg 期刊论文 Hejing Hu;Yanfeng Shi;Yannan Zhang;Jing Wu;Collins Otieno Asweto;Lin Feng;Xiaozhe Yang;Junchao Duan;Zhiwei Sun
22 Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells 期刊论文 Jing Wu;Yanfeng Shi;Collins OtienoAsweto;Lin Feng;Xiaozhe Yang;Yannan Zhang;Hejing Hu;Junchao Duan;Zhiwei Sun
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