能量压力下INF2蛋白翻译后修饰动态调控内质网-线粒体互作的分子机制及其在内膜癌发生中的作用研究
91954106
2019
C0701.细胞器及亚细胞结构、互作与功能
高昆
重大研究计划
研究员
同济大学
73万元
INF2;翻译后修饰;线粒体(mitochondria);内质网(endoplasmic reticulum);线粒体分裂
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer | 期刊论文 | Shi Qing;Jin Xiaofeng;Zhang Pingzhao;Li Qian;Lv Zeheng;Ding Yan;He Huiying;Wang Yijun;He Yuanlong;Zhao Xiaying;Zhao Shi-Min;Li Yao;Gao Kun;Wang Chenji |
| 2 | JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway | 期刊论文 | Qin Lin;Zheng Chen;Wei Shi;Zeheng Lv;Xiaoping Wan;Kun Gao |
| 3 | Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP HIPK2 axis | 期刊论文 | Jin Xiaofeng;Qing Shi;Li Qian;Zhuang Hui;Shen Liliang;Li Jinhui;Qi Honggang;Lin Ting;Lin Zihan;Wang Jian;Cao Xinyi;Yang Jianye;Ma Qi;Cong Linghua;Xi Yang;Fang Shuai;Meng Xiaodan;Gong Zhaohui;Ye Meng;Wang Shuyun;Wang Chenji;Gao Kun |
| 4 | Role of RHO family interacting cell polarization regulators (RIPORs) in health and disease: Recent advances and prospects | 期刊论文 | Zeheng Lv;Yan Ding;Wenxin Cao;Shuyun Wang;Kun Gao |
| 5 | SPOP mutation induces DNA methylation via stabilizing GLP/G9a | 期刊论文 | Zhang Jianong;Gao Kun;Xie Hongyan;Wang Dejie;Zhang Pingzhao;Wei Ting;Yan Yuqian;Pan Yunqian;Ye Wenbin;Chen Huifen;Shi Qing;Li Yao;Zhao Shi-min;Hou Xiaonan;Weroha Saravut J.;Wang Yuzhuo;Zhang Jun;Karnes R. Jeffrey;He Housheng Hansen;Wang Liguo;Wang Chenji;Huang Haojie |
| 6 | Enhanced autophagy and NFE2L2/NRF2 pathway activation in SPOP mutation-driven prostate cancer | 期刊论文 | Kun Gao;Qing Shi;Yajuan Liu;Chenji Wang |
| 7 | SPOP mutations promote tumor immune escape in endometrial cancer via the IRF1-PD-L1 axis | 期刊论文 | Kun Gao;Qing Shi;Ye Gu;Wanqi Yang;Yuanlong He;Zeheng Lv;Yan Ding;Wenxin Cao;Chenji Wang;Xiaoping Wan |
| 8 | p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer | 期刊论文 | Wen Xiaoli;Wan Jing;He Qizhi;Wang Mengfei;Li Shuangdi;Jiang Mei;Qian Zhen;Liu Binya;Lu Wen;Wang Kai;Gao Kun;Wan Xiaoping |
| 9 | CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14ARF degradation | 期刊论文 | Pingzhao Zhang;Kun Gao;Liang Zhang;Huiru Sun;Xiaying Zhao;Yajuan Liu;Zeheng Lv;Qing Shi;Yingji Chen;Dongyue Jiao;Yao Li;Wei Gu;Chenji Wang |
| 10 | Loss-of-function mutations of SOX17 lead to YAP/TEAD activation-dependent malignant transformation in endometrial cancer | 期刊论文 | Mengfei Wang;Qin Yan;Yunfeng Song;Zhenbo Zhang;Xiaojun Chen;Kun Gao;Xiaoping Wan |
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