YAP与O-GlcNAc修饰系统相互协同促进细胞代谢的“恶变”加速肝癌的发展
81572330
2015
H1807.肿瘤代谢
潘秋辉
面上项目
研究员
同济大学
65万元
Hippo/YAP通路;细胞代谢;O-;肝癌;GlcNAcylation
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Knockdown of NRAGE induces odontogenic differentiation by activating NF-kappa B signaling in mouse odontoblast-like cells | 期刊论文 | Wu Qi;Li Jing;Song Pingping;Chen Jing;Xu Yuanzhi;Qi Shengcai;Ma Ji;Pan Qiuhui |
| 2 | CircHMGCS1 Promotes Hepatoblastoma Cell Proliferation by Regulating the IGF Signaling Pathway and Glutaminolysis | 期刊论文 | Zhen Ni;Gu Song;Ma Ji;Zhu Jiabei;Yin Minzhi;Xu Min;Wang Jing;Huang Nan;Cui Zhongqi;Bian Zhixuan;Sun Fenyong;Pan Qiuhui |
| 3 | O-GlcNAcylation of YY1 stimulates tumorigenesis in colorectal cancer cells by targeting SLC22A15 and AANAT | 期刊论文 | Zhu Guoqing;Qian Mingping;Lu Liesheng;Chen Yan;Zhang Xiao;Wu Qi;Liu Ya;Bian Zhixuan;Yang Yueyue;Guo Susu;Wang Jiayi;Pan Qiuhui;Sun Fenyong |
| 4 | Sirt1 suppresses Wnt/beta Catenin signaling in liver cancer cells by targeting beta Catenin in a PKA alpha-dependent manner | 期刊论文 | Wu Qi;Wang Yulan;Qian Mingping;Qiao Yongxia;Zou Shaowu;Chen Changqiang;Zhang Xiao;Chen Yan;Zhao Yinghui;Zhu Guoqing;Chen Yuxin;Sun Fenyong;Wang Jiayi;Pan Qiuhui |
| 5 | RAP80 is an independent prognosis biomarker for the outcome of patients with esophageal squamous cell carcinoma | 期刊论文 | Yang Qingyuan;Lin Wanrun;Liu Zhiwei;Zhu Jiabei;Huang Nan;Cui Zhongqi;Han Zeping;Pan Qiuhui;Goel Ajay;Sun Fenyong |
| 6 | Ferroptosis is governed by differential regulation of transcription in liver cancer | 期刊论文 | Zhang Xiao;Du Lutao;Qiao Yongxia;Zhang Xiaobai;Zheng Weisheng;Wu Qi;Chen Yan;Zhu Guoqing;Liu Ya;Bian Zhixuan;Guo Susu;Yang Yueyue;Ma Lifang;Yu Yongchun;Pan Qiuhui;Sun Fenyong;Wang Jiayi |
| 7 | 靶向抑制高表达HRR蛋白增强肿瘤细胞对放化疗的敏感性 | 期刊论文 | 朱佳蓓;黄楠;崔中奇;杨庆源;潘秋辉 |
| 8 | Ginsenoside Rg1 impairs homologous recombination repair by targeting CtBP-interacting protein and sensitizes hepatoblastoma cells to DNA damage | 期刊论文 | Zhen Ni;Jin Lei;Ma Ji;Zhu Jiabei;Gu Song;Wang Jing;Pan Qiuhui;Ni Xiaorong;Xu Min |
| 9 | TFCP2 Is Required for YAP-Dependent Transcription to Stimulate Liver Malignancy | 期刊论文 | Zhang Xiao;Sun Fenyong;Qiao Yongxia;Zheng Weisheng;Liu Ya;Chen Yan;Wu Qi;Liu Xiangfan;Zhu Guoqing;Chen Yuxin;Yu Yongchun;Pan Qiuhui;Wang Jiayi |
| 10 | NRAGE induces beta-catenin/Arm O-GlcNAcylation and negatively regulates Wnt signaling | 期刊论文 | Chen Yuxin;Jin Lei;Xue Bin;Jin Dong;Sun Fenyong;Wen Chuanjun |
| 11 | Global profiling of O-GlcNAcylated and/or phosphorylated proteins in hepatoblastoma | 期刊论文 | Song Hang;Ma Ji;Bian Zhixuan;Chen Shuhua;Zhu Jiabei;Wang Jing;Huang Nan;Yin Minzhi;Sun Fenyong;Xu Min;Pan Qiuhui |
| 12 | m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma | 期刊论文 | Liu Li;Wang Jing;Sun Guifeng;Wu Qiong;Ma Ji;Zhang Xin;Huang Nan;Bian Zhixuan;Gu Song;Xu Min;Yin Minzhi;Sun Fenyong;Pan Qiuhui |
| 13 | Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells | 期刊论文 | Huang Nan;Liu Zhiwei;Zhu Jiabei;Cui Zhongqi;Li Yuguang;Yu Yongchun;Sun Fenyong;Pan Qiuhui;Yang Qingyuan |
| 14 | The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis | 期刊论文 | Zhang Xiao;Qiao Yongxia;Wu Qi;Chen Yan;Zou Shaowu;Liu Xiangfan;Zhu Guoqing;Zhao Yinghui;Chen Yuxin;Yu Yongchun;Pan Qiuhui;Wang Jiayi;Sun Fenyong |
| 15 | Reciprocal regulation between beta TrCP and Smurf1 suppresses proliferative capacity of liver cancer cells | 期刊论文 | Zhang Yue;Wang Wenhua;Cai Si;Chen Yan;Wang Qinwan;Pan Qiuhui;Sun Fenyong;Wang Jiayi |
| 16 | Characterization of hsa_circ_0000594 as a new biomarker and therapeutic target for hepatoblastoma | 期刊论文 | Song H;Bian Z X;Li H Y;Zhang Y;Ma J;Chen S H;Zhu J B;Zhang X;Wang J;Gu S;Xu M;Pan Q H;Yin M Z;Zheng L |
| 17 | Angiopoietin-2 (Ang-2) is a useful serum tumor marker for liver cancer in the Chinese population | 期刊论文 | Chen Yuxin;Wu Yanping;Zhang Xiao;Zeng Hong;Liu Ya;Wu Qi;Chen Yan;Zhu GuoQing;Pan Qiuhui;Jin Lei;Guo Lin;Sun Fenyong |
| 18 | High glucose stimulates proliferative capacity of liver cancer cells possibly via O-GlcNAcylation-dependent transcriptional regulation of GJC1 | 期刊论文 | Chen Yan;Liu Rui;Chu Zhexuan;Le Bu;Zeng Hong;Zhang Xiao;Wu Qi;Zhu Guoqing;Chen Yuxin;Liu Ya;Sun Fenyong;Lu Zhicheng;Qiao Yongxia;Wang Jiayi |
| 19 | High glucose stimulates proliferative capacity of liver cancer cells possibly via O-GlcNAcylation-dependent transcriptional regulation of GJC1 | 期刊论文 | Chen Yan;Liu Rui;Chu Zhexuan;Le Bu;Zeng Hong;Zhang Xiao;Wu Qi;Zhu Guoqing;Chen Yuxin;Liu Ya;Sun Fenyong;Lu Zhicheng;Qiao Yongxia;Wang Jiayi |
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