低密度脂蛋白受体相关蛋白与心脏电稳态维持和心律失常发生的关系

81530017
2015
H0204.心电活动异常与心律失常
陈义汉
重点项目
教授
同济大学
274万元
心脏生物电;心律失常;低密度脂蛋白受体相关蛋白;离子通道
2016-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 LRP6 downregulation promotes cardiomyocyte proliferation and heart regeneration 期刊论文 Wu Y;Zhou L;Liu H;Duan R;Zhou H;Zhang F;He X;Lu D;Xiong K;Xiong M;Zhuang J;Liu Y;Li L;Liang D;Chen YH
2 马尾松树皮提取物在制备移植器官保存液中的应用 专利 崔映宇;李梦琪;李响;李俊;陈义汉
3 Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum 期刊论文 Gao X;Gao S;Guan Y;Huang L;Huang J;Lin L;Liu Y;Zhao H;Huang B;Yuan T;Liu Y;Liang D;Zhang Y;Ma X;Li L;Li J;Zhou D;Shi D;Xu L;Chen YH
4 Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity 期刊论文 Guan Y;Gao X;Tang Q;Huang L;Gao S;Yu S;Huang J;Li J;Zhou D;Zhang Y;Shi D;Liang D;Liu Y;Li L;Cui Y;Xu L;Chen YH
5 稳定表达人内源性INav的细胞模型及其制备方法和用途 专利 陈义汉等
6 Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons 期刊论文 Liang D;Xue ZG;Xue JF;Xie D;Xiong K;Zhou HX;Zhang FL;Su XL;Wang GH;Zou QC;Liu Y;Yang J;Ma H;Peng LY;Zeng CY;Li G;Wang L;Chen YH
7 Cold-inducible RNA-binding protein prevents an excessive heart rate response to stress by targeting phosphodiesterase 期刊论文 Xie DY;Geng L;Xiong K;Zhao T;Wang S;Xue JF;Wang C;Wang GH;Feng ZQ;Zhou HX;Li YN;Li L;Liu Y;Xue ZG;Yang J;Ma H;Liang D;Chen YH
8 Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing 期刊论文 Yuan T;Wang S;Hu C;Wu Y;Liang D;Li L;Liu Y;Li J;Chen YH
9 Cold-inducible RNA-binding protein modulates atrial fibrillation onset by targeting multiple ion channels 期刊论文 Xie D;Geng L;Wang S;Xiong K;Zhao T;Wang G;Feng Z;Lv F;Wang C;Liang D;Shi D;Ma X;Liu Y;Yang J;Zhang C;Chen YH
10 USE OF HETEROCYCLIC DERIVATIVES WITH CARDIOMYOCYTE PROLIFERATION ACTIVITY FOR TREATMENT OF HEART DISEASES 专利 陈义汉等
11 Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing 期刊论文 Liang D;Xue JF;Geng L;Zhou LP;Lv B;Zeng Q;Xiong K;Zhou HX;Xie DY;Zhang FL;Liu J;Liu Y;Li L;Yang J;Xue ZG;Chen YH
12 REEP5 (receptor accessory protein 5) acts as a sarcoplasmic reticulum membrane sculptor to modulate cardiac function 期刊论文 Yao L;Xie D;Geng L;Shi D;Huang J;Wu Y;Lv F;Liang D;Li L;Liu Y;Li J;Chen YH
13 NOVEL HETEROCYCLIC DERIVATIVES WITH CARDIOMYOCYTE PROLIFERATION ACTIVITY FOR TREATMENT OF HEART DISEASES 专利 陈义汉等
14 一种稳定产生人内源性Ito、IKs电流的细胞模型及构建方法与应用 专利 陈义汉等
15 LRP5 controls cardiac QT interval by modulating the metabolic homeostasis of L-type calcium channel 期刊论文 Liang D;Wu Y;Zhou L;Chen Y;Liu H;Xie D;Huang J;Zhang Y;Liu Y;Zhu W;Li J;Chen YH
16 一种靶向细胞核的序列及其应用 专利 陈义汉等
17 The regulatory role of histone modification on gene expression in the early stage of myocardial infarction 期刊论文 Wang J;Lin B;Zhang Y;Ni L;Hu L;Yang J;Xu L;Shi D;Chen YH
18 核孔蛋白Nup54及其载体和重组腺病毒的用途 专利 陈义汉等
19 SNX 17 (Sorting Nexin 17) mediates atrial fibrillation onset through endocytic trafficking of the Kv1.5 (potassium voltage-gated channel subfamily a member 5) channel 期刊论文 Geng L;Wang S;Zhang F;Xiong K;Huang J;Zhao T;Shi D;Lv F;Li L;Liang D;Cui Y;Liu Y;Xie D;Chen YH
20 Endothelial Tomm7-Rac1 signaling axis dominates cerebrovascular network homeostasis 期刊论文 Shi D;Qi M;Zhou LP;Li X;Ni L;Li CM;Yuan TY;Wang YQ;Chen YL;Hu CY;Liang DD;Li L;Liu Y;Li J;Chen YH
21 ION CHANNEL ANTAGONISTS/BLOCKERS AND USES THEREOF 专利 陈义汉等
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