IL-27在银屑病中调节IL-17A-REG3A轴的作用机制研究

81872522
2018
H1202.皮肤免疫性疾病
史玉玲
面上项目
教授
同济大学
57万元
银屑病;REG3A;γδT细胞;IL-27
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A Case of Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type with Dermatomyositis 期刊论文 Yu Gong;Ke Xue;Yifan Hu;Rong Wei;Yeqiang Liu;Hua Cao;Yuling Shi
2 A distinct immature low-density neutrophil population characterizes acute generalized pustular psoriasis 期刊论文 Ning Yu;Hui Qin;Yingyuan Yu;Ying Li;Jiajing Lu;Yuling Shi
3 Abnormal lipid metabolism in epidermal Langerhans cells mediates psoriasis-like dermatitis 期刊论文 Xilin Zhang;Xiaorui Li;Yuanyuan Wang;Youdong Chen;Yijun Hu;Chunyuan Guo;Zengyang Yu;Peng Xu;Yangfeng Ding;Qing-Sheng Mi;Jianhua Wu;Jun Gu;Yuling Shi
4 Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions 期刊论文 Xin Wang;Rui Ma;Xilin Zhang;Lian Cui;Yangfeng Ding;Weimin Shi;Chunyuan Guo;Yuling Shi
5 Infliximab modifies regulatory T cells and co-inhibitory receptor expression on circulating T cells in psoriasis 期刊论文 Yingyuan Yu;Zeyu Chen;Yu Wang;Ying Li;Jiajing Lu;Lian Cui;Zengyang Yu;Yangfeng Ding;Chunyuan Guo;Xilin Zhang;Yuling Shi
6 IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients 期刊论文 Yuling Shi;Zeyu Chen;Zihan Zhao;Yingyuan Yu;Huayu Fan;Xiaoguang Xu;Xiaolin Bu;Jun Gu
7 RNA modifications: importance in immune cell biology and related diseases 期刊论文 Lian Cui;Rui Ma;Jiangluyi Cai;Chunyuan Guo;Zeyu Chen;Lingling Yao;Yuanyuan Wang;Rui Fan;Xin Wang;Yuling Shi
8 Current Research and Use of Mesenchymal Stem Cells in the Therapy of Autoimmune Diseases 期刊论文 Youdong Chen;Qian Yu;Yifan Hu;Yuling Shi
9 Based on Gene Expression Analysis: Low-Density Neutrophil Expression Is a Characteristic of the Fast Responders Treated With Guselkumab for Psoriasis 期刊论文 Jiajing Lu;Yu Wang;Ying Li;Xiaoyuan Zhong;Yu Gong;Yangfeng Ding;Ning Yu;Yuling Shi
10 Pustular psoriasis appearing in a Chinese woman treated with dupilumab for atopic dermatitis: A case report 期刊论文 Xiaoyuan Zhong;Ying Li;Yunlu Gao;Ying Zhang;Jiajing Lu;Ning Yu;Yangfeng Ding;Yuling Shi
11 Advances in the pathogenesis of psoriasis: from keratinocyte perspective 期刊论文 Xue Zhou;Youdong Chen;Lian Cui;Yuling Shi;Chunyuan Guo
12 A review of disease burden and clinical management for generalized pustular psoriasis in China 期刊论文 Jiajing Lu;Yuling Shi
13 Discovering Novel Biomarkers Associated with the Pathogenesis of Psoriasis: Evidence from Bioinformatic Analysis 期刊论文 Yang Yang;Shaoqiong Xie;Wencheng Jiang;Suwei Tang;Yuling Shi
14 Safety and efficacy of secukinumab in psoriasis patients infected with hepatitis B virus: a retrospective study 期刊论文 Hui Qin;Na Liu;Yifan Hu;Ning Yu;Xuemei Yi;Yunlu Gao;Fujuan Chen;Jun Gu;Yangfeng Ding;Yuling Shi
15 Human umbilical cord-derived mesenchymal stem cells ameliorate psoriasis-like dermatitis by suppressing IL-17-producing γδ T cells 期刊论文 Youdong Chen;Yifan Hu;Xue Zhou;Zihan Zhao;Qian Yu;Zeyu Chen;Yuanyuan Wang;Peng Xu;Zengyang Yu;Chunyuan Guo;Xilin Zhang;Yuling Shi
16 A randomized prospective study of different dose regimens using the 308‐nm excimer laser in the treatment of palmoplantar pustulosis 期刊论文 Chen Peng;Yifan Hu;Wenjuan Chen;Yangfeng Ding;Xingzi Li;Ning Yu;Jiajing Lu;Yuling Shi
17 Ginsenoside compound K ameliorates imiquimod-induced psoriasis like dermatitis through inhibiting REG3A/RegIII gamma expression in keratinocytes 期刊论文 Fan Huayu;Wang Yao;Zhang Xilin;Chen Jinguang;Zhou Qianqian;Yu Zengyang;Chen Youdong;Chen Zeyu;Gu Jun;Shi Yuling
18 The efficacy and safety of dupilumab for the treatment of atopic dermatitis among Chinese patients in clinical practice: A single‐center retrospective study 期刊论文 Ying Li;Jiajing Lu;Rongfen Chen;Yu Wang;Yangfeng Ding;Shuang Xu;Ying Zou;Xuemei Yi;Yuling Shi
19 Lgr4 deletion delays the hair cycle and inhibits the activation of hair follicle stem cells 期刊论文 Xiaolin Ren;Weili Xia;Peng Xu;Hongyang Shen;Xing Dai;Mingyao Liu;Yuling Shi;Xiyun Ye;Yongyan Dang
20 Efficient local delivery of FK506 using blocking patches in psoriasis 期刊论文 Zihan Zhao;Huaiji Wang;Lingling Yao;Xilin Zhang;Qian Yu;Jun Gu;Yuling Shi
21 CircRAB3B suppresses proliferation, motility, cell cycle progression and promotes the apoptosis of IL-22-induced keratinocytes depending on the regulation of miR-1228-3p/PTEN axis in psoriasis 期刊论文 Jiajing Lu;Xin Xu;Ying Li;Ning Yu;Yangfeng Ding;Yuling Shi
22 一种用于治疗银屑病的多功能涂药装置 专利 陆家睛;史玉玲;丁杨峰;周静;于宁;唐苏为;李影;彭琛;陈文娟
23 308nm准分子光治疗掌跖脓疱病的有效性及安全性评价 期刊论文 王宇;彭琛;陆家睛;虞英媛;于倩;史玉玲
24 他扎罗汀倍他米松乳膏治疗慢性斑块型银屑病的临床疗效和安全性评价 期刊论文 周倩倩;陆家睛;胡艺凡;徐乐臻;邹颖;史玉玲
25 节律基因隐花色素2在银屑病小鼠模型及HaCaT细胞中的表达变化及机制研究 期刊论文 姚玲玲;余增洋;郭春源;周静;崔莲;于倩;虞英媛;周雪;蔡江鲁伊;史玉玲
26 银屑病共病的研究进展 期刊论文 陈文娟;彭琛;丁杨峰;史玉玲
27 Construction of a lncRNA-miRNA-mRNA network to determine the regulatory roles of lncRNAs in psoriasis 期刊论文 Zhou Qianqian;Yu Qian;Gong Yu;Liu Zhicui;Xu Hui;Wang Yao;Shi Yuling
28 Infliximab and biosimilar infliximab in psoriasis: efficacy, loss of efficacy, and adverse events 期刊论文 Subedi Smriti;Gong Yu;Chen Youdong;Shi Yuling
29 Interleukin-33 alleviates psoriatic inflammation by suppressing the T helper type 17 immune response 期刊论文 Chen Zeyu;Hu Yifan;Gong Yu;Zhang Xilin;Cui Lian;Chen Rongfen;Yu Yingyuan;Yu Qian;Chen Youdong;Diao Hongyue;Chen Jia;Wang Yuanyuan;Shi Yuling
30 IL-17A Promotes Psoriasis-Associated Keratinocyte Proliferation through ACT1-Dependent Activation of YAP–AREG Axis 期刊论文 Zengyang Yu;Qian Yu;Hui Xu;Xing Dai;Yingyuan Yu;Lian Cui;Youdong Chen;Jun Gu;Xilin Zhang;Chunyuan Guo;Yuling Shi
31 Secukinumab treatment for a psoriasis patient co‐infected with HIV and latent tuberculosis: A case report 期刊论文 Hui Qin;Jiajing Lu;Xuemei Yi;Yangfeng Ding;Yuling Shi
32 Efficacy and safety of etanercept combined plus methotrexate and comparison of expression of pro-inflammatory factors expression for the treatment of moderate-to-severe plaque psoriasis 期刊论文 Qian Yu;Yunlei Tong;Lian Cui;Lingling Zhang;Yu Gong;Hongyue Diao;Fei Gao;Yuling Shi
33 Circulating Metabolomic Signature in Generalized Pustular Psoriasis Blunts Monocyte Hyperinflammation by Triggering Amino Acid Response 期刊论文 Ning Yu;Chen Peng;Wenjuan Chen;Ziwen Sun;Jianfeng Zheng;Shujie Zhang;Yangfeng Ding;Yuling Shi
34 Cardiometabolic Comorbidities in Patients With Psoriasis: Focusing on Risk, Biological Therapy, and Pathogenesis 期刊论文 Jiangluyi Cai;Lian Cui;Yu Wang;Ying Li;Xilin Zhang;Yuling Shi
35 5-十四烷氧基-2-呋喃甲酸在制备用于治疗银屑病样皮炎的药物中的用途 专利 张希琳;史玉玲;顾军;丁杨峰
36 Epidemiological variations in global burden of atopic dermatitis: An analysis of trends from 1990 to 2019 期刊论文 Chen Peng;Ning Yu;Yangfeng Ding;Yuling Shi
37 Cutaneous phaeohyphomycosis caused by Pyrenochaeta unguis-hominis in a diabetic patient: A case report 期刊论文 Gong Yu;Chen Zeyu;Ma Yue'e;Jiang Weiwei;Hu Yifan;Shi Yuling
38 Fargesin inhibits melanin synthesis in murine malignant and immortalized melanocytes by regulating PKA/CREB and P38/MAPK signaling pathways 期刊论文 Ting Fu;Bowen Chai;Yuling Shi;Yongyan Dang;Xiyun Ye
39 Efficacy and safety of two hyaluronic acid fillers with different injection depths for the correction of moderate‐to‐severe nasolabial folds: A 52‐week, prospective, randomized, double‐blinded study in a Chinese population 期刊论文 Yifan Hu;Zhiyu Liu;Yao Wang;Qian Yu;Yu Gong;Hongyue Diao;Yi Jin;Shuqin Zhang;Yuling Shi
40 Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients 期刊论文 Yifan Hu;Youdong Chen;Zeyu Chen;Xiaomei Zhang;ChunYuan Guo;ZengYang Yu;Peng Xu;Lei Sun;Xinying Zhou;Yu Gong;Qian Yu;Yuling Shi
41 Novel Targeted Biological Agents for the Treatment of Atopic Dermatitis 期刊论文 Nan Yang;Zeyu Chen;Xilin Zhang;Yuling Shi
42 中国银屑病生物治疗专家共识(2019版)解读 期刊论文 陆家睛;史玉玲
43 Microneedles: a potential strategy in transdermal delivery and application in the management of psoriasis 期刊论文 Zihan Zhao;Youdong Chen;Yuling Shi
44 A case of primary cutaneous anaplastic large cell lymphoma on eyelid 期刊论文 Yu Gong;Jia Chen;Yuling Shi
45 Comparison of different incremental dose regimens of narrow-band ultraviolet B in skin types III to V: A prospective, randomized, single-blind, parallel study in patients with psoriasis 期刊论文 Yingyuan Yu;Xuemei Yi;Yi Zhang;Ning Yu;Qian Yu;Qianlian Le;Zeyu Chen;Yangfeng Ding;Yuling Shi
46 High-throughput transcriptome and pathogenesis analysis of clinical psoriasis 期刊论文 Yu Zengyang;Gong Yu;Cui Lian;Hu Yifan;Zhou Qianqian;Chen Zeyu;Yu Yingyuan;Chen Youdong;Xu Peng;Zhang Xilin;Guo Chunyuan;Shi Yuling
47 一种治疗银屑病的皮肤科用照射装置 专利 周静;史玉玲;唐苏为;陆家睛;李影;丁杨峰
48 Erythrokeratodermia variabilis et progressiva due to a novel mutation in GJB4 期刊论文 Xilin Zhang;Peng Xu;Jiajing Lu;Yangfeng Ding;Jun Gu;Yuling Shi
49 银屑病相关心理问题和精神障碍 期刊论文 史玉玲
50 Local reinfusion ofB10cells is effective in the treatment of pustular psoriasis 期刊论文 Lu Jiajing;Xu Xin;Li Ying;Yu Ning;Ding Yangfeng;Shi Yuling
51 Xiao-Yin-Fang Therapy Alleviates Psoriasis-like Skin Inflammation Through Suppressing γδT17 Cell Polarization 期刊论文 Xilin Zhang;Xiaorui Li;Youdong Chen;Bingjie Li;Chunyuan Guo;Peng Xu;Zengyang Yu;Yangfeng Ding;Yuling Shi;Jun Gu
52 Comparative Study on the Clinical Efficacy and Safety of Acitretin and MTX in the Treatment of Pustular Psoriasis by TLR7/MyD88/CXCL16 Pathway 期刊论文 Jiajing Lu;Yu Wang;Ying Li;Yu Gong;Yangfeng Ding;Yuling Shi
53 Drug Survival Outcomes Associated with the Real-World Use of Ixekizumab, Secukinumab, Guselkumab, and Adalimumab for the Treatment of Plaque Psoriasis in China: A 52-Week Single-Center Retrospective Study 期刊论文 Ying Li;Jia-Jing Lu;Xiao-Yuan Zhong;Ying-Yuan Yu;Ning Yu;Yu Wang;Xue-Mei Yi;Yang-Feng Ding;Yu-Ling Shi
54 Emerging roles of circular RNAs in systemic lupus erythematosus 期刊论文 Xin Wang;Rui Ma;Weimin Shi;Zhouwei Wu;Yuling Shi
55 糠酸莫米松和他克莫司序贯疗法治疗面部化妆品接触性皮炎的临床研究 期刊论文 胡艺凡;于倩;刘芝翠;龚瑜;王瑶;史玉玲
56 Biologic and Small-Molecule Therapies for Moderate-to-Severe Psoriasis: Focus on Psoriasis Comorbidities 期刊论文 Yuxiong Jiang;Youdong Chen;Qian Yu;Yuling Shi
57 肿瘤坏死因子α介导银屑病脂肪酸去饱和酶2低表达 期刊论文 周雪;余增洋;陈有东;郭春源;于倩;胡艺凡;姚玲玲;史玉玲
58 Ixekizumab four-week dosing is comparable to two-week dosing in psoriasis patients and reduces treatment costs: experience in a real-world setting over a 12-week period 期刊论文 Ying Li;Yingyuan Yu;Yu Wang;Jiajing Lu;Xuemei Yi;Ning Yu;Yangfeng Ding;Yuling Shi
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