胆汁酸合成酶ACOX2变异重编心肌脂肪酸代谢并诱发肝硬化性心肌病的分子机制研究
81870285
2018
H0207.心肌炎和心肌病
周翔宇
面上项目
研究员
同济大学
60万元
动物疾病模型;血清胆汁酸;代谢性心肌病;肝硬化;ACOX2;基因
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Biallelic loss of function NEK3 mutations deacetylate α-tubulin and downregulate NUP205 that predispose individuals to cilia-related abnormal cardiac left-right patterning | 期刊论文 | Yuan Zhang;Weicheng Chen;Weijia Zeng;Zhouping Lu;Xiangyu Zhou |
| 2 | Acox2 is a regulator of lysine crotonylation that mediates hepatic metabolic homeostasis in mice | 期刊论文 | Yuan Zhang;Yuling Chen;Zhao Zhang;Xiang Tao;Sha Xu;Xinyan Zhang;Tinatin Zurashvili;Zhouping Lu;José Ramon Bayascas;Liping Jin;Jianyuan Zhao;Xiangyu Zhou |
| 3 | Bi-Allelic Mutations in NUP205 and NUP210 Are Associated With Abnormal Cardiac Left-Right Patterning | 期刊论文 | Weicheng Chen;Yuan Zhang;Sunhu Yang;Zhiwen Shi;Weijia Zeng;Zhouping Lu;Xiangyu Zhou |
| 4 | Two sides of NNMT in alcoholic and nonalcoholic fatty liver development | 期刊论文 | Yuan Zhang;Zhouping Lu;Weijia Zeng;Jianyuan Zhao;Xiangyu Zhou |
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