基于动态网络的复杂疾病分析理论和方法

91530320
2015
A0604.生物与生命科学中的数学
周天寿
重大研究计划
教授
中山大学
250万元
随机模拟算法;系统生物学;基因调控网络模型;计算系统生物学;生化反应系统
2016-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Structural Key Genes: Differentiating Lung Squamous Cell Carcinomas from Adenocarcinomas 期刊论文 Yansen Su;Zheng Zhang;Linqiang Pan
2 Accurate detection of time delays and directional interactions based on time series from complex dynamical systems 期刊论文 H.F. Ma;S.Y. Leng;C.Y. Tao;X. Ying;J. Kurths;Y-C Lai;W. Lin
3 完整基因表达模型中的精确分布 期刊论文 仇华海;周天寿
4 L Prediction and validation of association between microRNAs and diseases by multipath methods 期刊论文 Zeng Xiangxiang;Zhang Xuan;Liao Yuanlu;Pan Linqiang
5 Correction: Division time-based amplifiers for gene expression 期刊论文 Haohua Wang;Zhanjiang Yuan;Peijiang Liu;Tianshou Zhou
6 Detecting early- warning signals of influenza outbreak based on dynamic network marker 期刊论文 Chen Pei;Chen Ely;Chen Lounan;Xianghong Ja;Zhou Xianghong Jasmine;Liu Rui
7 Biomarker MicroRNAs for Diagnosis, Prognosis and Treatment of Hepatocellular Carcinoma: A Functional Survey and Comparison 期刊论文 Shen Sijia;Lin Yuxin;Yuan Xuye;Shen Li;Chen Jiajia;Chen Luonan;Qin Lei;Shen Bairong
8 Qualitative analysis of critical transitions in dynamical systems for complex diseases 期刊论文 Gang Wang;Xiufen Zou
9 Knowledge-Guided Bioinformatics Model for Identifying Autism Spectrum Disorder Diagnostic MicroRNA Biomarkers 期刊论文 Shen Li;Lin Yuxin;Sun Zhandong;Yuan Xuye;Chen Luonan;Shen Bairong
10 A fast overlapping community detection algorithm based on weak-cliques for large-scale networks 期刊论文 Xingyi Zhang;Congtao Wang;Yansen Su;Linqiang Pan;Hai-feng Zhang
11 A new centrality measure of nodes in multilayer networks under the framework of tensor computation 期刊论文 Wang Dingjie;Xiufen Zou
12 Predicting Essential Proteins Based on Gene Expression Data, Subcellular Localization and PPI Data 期刊论文 Xiujuan Lei;Siguo Wang;Linqiang Pan
13 Interlocked multi-node positive and negative feedback loops facilitate oscillations 期刊论文 Qingqing Li;Tianshou Zhou
14 A New Method for Identifying Essential Proteins by Measuring Co-Expression and Functional Similarity 期刊论文 Zhang Wei;Xu Jia;Li Xiong;Zou Xiufen
15 Decomposition and Tunability of Expression Noise in the Presence of Coupled Feedbacks 期刊论文 Peijiang Liu;Zhanjiang Yuan;Haohua Wang;Tianshou Zhou
16 Mathematical modeling and quantitative analysis of HIV-1 Gag trafficking and polymerization 期刊论文 Yuewu Liu;Xiufen Zou
17 Resource control of epidemic spreading through a multilayer network 期刊论文 Jian Jiang;Tianshou Zhou
18 Data-based prediction and causality inference of nonlinear dynamics 期刊论文 H.F. Ma;S.Y. Leng;L.N. Che
19 Mathematical modeling of HIV-like particle assembly in vitro 期刊论文 Liu Yuewu;Xiufen Zou
20 Randomly distributed embedding making short-term high-dimensional data predictable 期刊论文 H.F. Ma;S.Y. Leng;K. Aihara;W. Lin;L.N. Chen
21 The free-energy cost of interaction between DNA loops 期刊论文 Huang Lifang;Yu Jianshe;Huang Lifang;Liu Peijiang;Yuan Zhanjiang;Zhou Tianshou;Yu JS;Zhou TS
22 Several indicators of critical transitions for complex biological systems based on stochastic analysis 期刊论文 Gang Wang;Yuanyuan Li;Xiufen Zou
23 Identifying key nodes in multilayer networks based on tensor decomposition 期刊论文 Wang Dingjie;Haitao Wang;Xiufen Zou
24 The influence of time delay on epidemic spreading under limited resources 期刊论文 Jian Jiang;Tianshou Zhou
25 Identifying disease modules and components of viral infections based on multi-layer networks 期刊论文 Li Yuanyuan;Zou Xiufen
26 Mechanisms of information decoding through a cascade system of gene expression 期刊论文 Haohua Wang;Zhanjiang Yuan;Peijiang Liu;Tianshou Zhou
27 A moment-convergence method for stochastic analysis ofbiochemical reaction networks 期刊论文 Jiajun Zhang;Qing Nie;Tianshou Zhou
28 Identifying disease modules and components of viral infections based on multi-layer networks 期刊论文 Yuanyuan Li;Xiufen Zou
29 An algorithm based on positive and negative links for community detection in signed networks 期刊论文 Su Yansen;Wang Bangju;Cheng Fan;Zhang Lei;Zhang Xingyi;Pan Linqiang
30 Effectof Interaction between Chromatin Loops on Cell-to-Cell Variability in GeneExpression 期刊论文 Tuoqi Liu;Jiajun Zhang;Tianshou Zhou
31 Detecting Coordinated Regulations of Pathways By Higher Logic Analysis 会议论文 Su Yansen;Zhang Xingyi;Pan Linqiang;Pan LQ
32 On the System Entropy and Energy Dissipativity of Stochastic Systems and Their Application in Biological Systems 期刊论文 Bor-Sen Chen;Xiangyun Lin;Weihai Zhang;Tianshou Zhou
33 Linear approximations of global behaviors in nonlinear dynamical systems with noise 期刊论文 Junhao Liang;Anwarud Din;Tianshou Zhou
34 Detecting critical transitions in the big noise case by binomial moments 期刊论文 Anwarud Din;Junhao Liang;Tianshou Zhou
35 A universal indicator of critical state transitions in noisy complex networked systems 期刊论文 Junhao Liang;Yanqing Hu;Guanrong Chen;Tianshou Zhou
36 Feedback-induced Critical Behavior in Binary Propagation Processes on Complex Networks 期刊论文 Junhao Liang;Tianshou Zhou
37 Breakdown of interdependent directed networks 期刊论文 Xueming Liu;H. Eugene Stanley;Jianxi Gao
38 Detecting critical state before phase transition of complex biological systems by hidden Markov model 期刊论文 Chen Pei;刘锐;Li Yongjun;Chen Luonan.
39 ElciRNA-mediated gene expression: tunability and bimodality 期刊论文 Qi Hu;Tianshou Zhou
40 Division time-based amplifiers for stochastic gene expression (vol 11, pg 2417, 2015) 期刊论文 Wang Haohua;Yuan Zhanjiang;Liu Peijiang;Zhou Tianshou
41 Characteristicsof promoter structure-dependent expression noise and bursting kinetics 期刊论文 Heli Tan;Zhanjiang Yuan;Jiajun Zhang;Tian Shou Zhou
42 Trajectory control in nonlinear networked systems and its applications to complex biological systems 期刊论文 Suoqin Jin;Dingjie Wang;Xiufen Zou
43 Detecting the tipping points in a three-state model of complex diseases by temporal differential networks 期刊论文 Chen Pei;Li Yongjun;Liu Rui;Chen Luonan
44 Optimization of controllability and robustness of complex networks by edge directionality 期刊论文 Man Liang;Suoqin Jin;Dingjie Wang;Xiufe Zou
45 Quantifying critical states of complex diseases using single-sample dynamic network biomarkers 期刊论文 Liu Xiaoping;Chang Xiao;Chen Luonan;Aihara Kazuyuki;Liu Xiaoping;Chang Xiao;Liu Xiaoping;Yu Xiangtian;Chen Luonan;Liu Xiaoping;Liu Rui;Chen Luonan;Chen LN;Aihara K;Chen LN;Chen LN
46 The dynamic mechanism of noisy signal decoding in gene regulation 期刊论文 Peijiang Liu;Haohua Wang;Lifang Huang;Tiansh Zhou
47 Hunt for the tipping point during endocrine resistance process in breast cancer by dynamic network biomarkers 期刊论文 Liu Rui;Wang Jinzeng;Ukai Masao;Sewon Ki;Chen Pei;Suzuki Yutaka;Wang Haiyun;Aihara Kazuyuki;Okada-Hatakeyama Mariko;Chen Luonan
48 Long Non-coding RNAs in Urologic Malignancies: Functional Roles and Clinical Translation 期刊论文 Chen Jiajia;Miao Zhijun;Xue Boxin;Shan Yuxi;Weng Guobin;Shen Bairong
49 Entangled signal pathways can both control expression stability and induce stochastic focusing 期刊论文 Haohua Wang;Peijiang Liu;Qingqing Li;Tianshou Zhou
50 Random positioning of nucleosomes enhances heritable bistability 期刊论文 Heli Tan;Tuoqi Liu;Jiajun Zhang;Tianshou Zhou
51 Detecting the tipping points in a three-state model of complex diseases by temporal differential networks 期刊论文 Chen Pei;Li Yongjun;Liu Xiaoping;Liu Rui;Chen Luonan
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