肾脏血管肾素原受体在肾脏血流动力学及血管紧张素Ⅱ诱导的高血压及肾脏血管重构中的作用

91439205
2014
H0213.血压调节异常与高血压病
杨天新
重大研究计划
教授
中山大学
270万元
肾素原受体；肾血流动力学；肾素-血管紧张素系统；高血压；血管重构
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Systemic PPAR gamma deletion causes severe disturbance in fluid homeostasis in mice 期刊论文 Zhou Li;Panasiuk Alexandra;Downton Maicy;Zhao Daqiang;Yang Baoxue;Jia Zhanjun;Yang Tianxin
2 (Pro)Renin receptor regulates potassium homeostasis through a local mechanism 期刊论文 Chuanming Xu;Aihua Lu;Hong Wang;Hui Fang;Li Zhou;Peng Sun;Tianxin Yang
3 Collecting duct (pro)renin receptor targets ENaC to mediate angiotensin II-induced hypertension 期刊论文 Peng Kexin();Lu Xiaohan;Wang Fei;Nau Adam;Chen Ren;Zhou Shu Feng;Yang Tianxin()
4 Regulation and function of renal medullary cyclooxygenase-2 during high salt loading 期刊论文 Yang Tianxin()();Liu Mi
5 (Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells 期刊论文 Fang Hui();Xu Chuanming;Lu Aihua;Zou Chang Jiang;Xie Shiying;Chen Yanting;Zhou Li;Liu Mi;Wang Lei;Wang Weidong;Yang Tianxin()
6 Soluble (Pro)Renin Receptor as a Potential Therapy for Diabetes Insipidus 期刊论文 Kevin T Yang();Tianxin Yang;J David Symons
7 Activation of ENaC in collecting duct cells by prorenin and its receptor PRR: involvement of Nox4-derived hydrogen peroxide 期刊论文 Lu Xiaohan();Wang Fei;Liu Mi;Yang Kevin T;Nau Adam;Kohan Donald E;Reese Van;Richardson Russell S;Yang Tianxin()
8 High potassium promotes mutual interaction between (pro)renin receptor and the local renin-angiotensin-aldosterone system in rat inner medullary collecting duct cells 期刊论文 Chuanming Xu;Hui Fang;Li Zhou;Aihua Lu;Tianxin Yang
9 Antidiuretic Action of Collecting Duct (Pro)Renin Receptor Downstream of Vasopressin and PGE(2) Receptor EP4 期刊论文 Wang Fei();Lu Xiaohan;Peng Kexin;Fang Hui;Zhou Li;Su Jiahui;Nau Adam;Yang Kevin T;Ichihara Atsuhiro;Lu Aihua;Zhou Shu Feng;Yang Tianxin()
10 Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro) renin receptor and intrarenal renin-angiotensin system 期刊论文 Wang Lei();Zhu Qing;Lu Aihua;Liu Xiaofen;Zhang Linlin;Xu Chuanming;Liu Xiyang;Li Haobo;Yang Tianxin()
11 Activation of Renal (Pro)Renin Receptor Contributes to High Fructose-Induced Salt Sensitivity 期刊论文 Chuanming Xu;Aihua Lu;Xiaohan Lu;Linlin Zhang;Hui Fang;Li Zhou;Tianxin Yang
12 Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin-angiotensin system 期刊论文 Wang F Lu X Liu M Feng Y Zhou SF;Yang T()
13 Role of (Pro)Renin Receptor in Albumin Overload-Induced Nephropathy in Rats 期刊论文 Fang Hui;Deng Mokan;Zhang Linlin;Lu Aihua;Su Jiahui;Xu Chuanming;Zhou Li;Wang Lei;Ou Jing-Song;Wang Weidong;Yang Tianxin
14 Physiology and Pathophysiology of the Intrarenal Renin-Angiotensin System: An Update 期刊论文 Yang T;Xu C
15 Crosstalk between (Pro)renin receptor and COX-2 in the renal medulla during angiotensin II-induced hypertension 期刊论文 Yang Tianxin()()
16 The soluble (Pro) renin receptor does not influence lithium-induced diabetes insipidus but does provoke beiging of white adipose tissue in mice 期刊论文 Kevin T. Yang();Fei Wang;Xiaohan Lu;Kexin Peng;Tianxin Yang();J. David Symons
17 Enzymatic sources and physio-pathological functions of soluble (pro)renin receptor 期刊论文 Zhu Qing;Yang Tianxin
18 Deficiency of mPGES-1 exacerbates renal fibrosis and inflammation in mice with unilateral ureteral obstruction 期刊论文 Luo Renfei();Kakizoe Yutaka;Wang Feifei;Fan Xiang;Hu Shan;Yang Tianxin;Wang Weidong;Li Chunling()
19 NF-kappa B-dependent upregulation of (pro)renin receptor mediates high-NaCl-induced apoptosis in mouse inner medullary collecting duct cells 期刊论文 Su Jiahui();Liu Xiyang;Xu Chuanming;Lu Xiaohan;Wang Fei;Fang Hui;Lu Aihua;Qiu Qixiang;Li Chunling;Yang Tianxin()
20 Specific downregulation of cystathionine beta-synthase expression in the kidney during obesity 期刊论文 Liu M();Deng M;Su J;Lin Y;Jia Z;Peng K;Wang F;Yang T()
21 Role of COX-2 in unilateral ureteral obstruction: what is new? 期刊论文 Yang Tianxin()();Li Chunling
22 Site-1 protease-derived soluble (pro)renin receptor targets vasopressin receptor 2 to enhance urine concentrating capability. 期刊论文 Wang F();Xu C;Luo R;Peng K;Ramkumar N;Xie S;Lu X;Zhao L;Zuo C-J;Kohan DE;Yang T.()
23 (Pro)Renin Receptor Contributes to Pregnancy-Induced Sodium-Water Retention in Rats via Activation of Intrarenal RAAS and α-ENaC 期刊论文 Ziwei Fu();Jiajia Hu;Li Zhou;Yanting Chen;Mokan Deng;Xiyang Liu;Jiahui Su;Aihua Lu;Tianxin Yang()
24 Soluble (pro)renin receptor via beta-catenin enhances urine concentration capability as a target of liver X receptor 期刊论文 Lu X;Wang F;Xu C;Soodvilai S;Peng K;Su J;Zhao L;Yang K;Feng Y;Zhou S;Gustafsson J;Yang T
25 Unraveling the Physiology of (Pro)Renin Receptor in the Distal Nephron 期刊论文 Yang Tianxin()()
26 Protection of nitro-fatty acid against kidney diseases 期刊论文 杨天新
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