集调控病灶核心区再生微环境和强化内源性修复为一体的干细胞工程化治疗系统用于脑卒中修复和再生研究

92068110
2020
H3408.药剂学
陈钧
重大研究计划
教授
复旦大学
80万元
微环境调控;脑卒中;干细胞移植;细胞工程;纳米技术
2021-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 一种间充质干细胞凋亡囊泡递释系统及其构建方法和应用 专利 陈钧;尤洋
2 Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy 期刊论文 Xu Minjun;Hu Kaili;Liu Yipu;Huang Yukun;Liu Shanshan;Chen Yu;Wang Dayuan;Zhou Songlei;Zhang Qian;Mei Ni;Lu Huiping;Li Fengan;Gao Xiaoling;Chen Jun
3 Synthetically Lethal Biomimetic Nutri-hijacker Hitchhikes and Reprograms KRAS Mutation-Driven Metabolic Addictions for Pancreatic Ductal Adenocarcinoma Treatment 期刊论文 Yukun Huang;Yu Chen;Songlei Zhou;Laozhi Xie;Kaifan Liang;Jianpei Xu;Qian Zhang;Huan Chen;Dayuan Wang;Qingxiang Song;Gan Jiang;Ni Mei;Fenfen Ma;Huiping Lu;Xiaoling Gao;Jun Chen
4 Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment 期刊论文 Tianze Jiang;Laozhi Xie;Songlei Zhou;Yu Liu;Yukun Huang;Ni Mei;Fenfen Ma;Jingru Gong;Xiaoling Gao;Jun Chen
5 上海市优秀学术带头人 奖励 陈钧
6 Neutrophil-Biomimetic “Nanobuffer” for Remodeling the Microenvironment in the Infarct Core and Protecting Neurons in the Penumbra via Neutralization of Detrimental Factors to Treat Ischemic Stroke 期刊论文 Shanshan Liu;Jianpei Xu;Yipu Liu;Yang You;Laozhi Xie;Shiqiang Tong;Yu Chen;Kaifan Liang;Songlei Zhou;Fengan Li;Zhuang Tang;Ni Mei;Huiping Lu;Xiaolin Wang;Xiaoling Gao;Jun Chen
7 Bioorthogonal microglia-inspired mesenchymal stem cell bioengineering system creates livable niches for enhancing ischemic stroke recovery via the hormesis 期刊论文 Xu Jianpei;Sun Yinzhe;You Yang;Zhang Yuwen;Huang Dan;Zhou Songlei;Liu Yipu;Tong Shiqiang;Ma Fenfen;Song Qingxiang;Dai Chengxiang;Li Suke;Lei Jigang;Wang Zhihua;Gao Xiaoling;Chen Jun
8 Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma 期刊论文 Zhou Songlei;Huang Yukun;Chen Yu;Liu Yipu;Xie Laozhi;You Yang;Tong Shiqiang;Xu Jianpei;Jiang Gan;Song Qingxiang;Ni Mei;Ma Fenfen;Gao Xiaoling;Chen Hongzhuan;Chen Jun
9 Surface-tethered ROS-responsive micelle backpacks for boosting mesenchymal stem cell vitality and modulating inflammation in ischemic stroke treatment 期刊论文 Yang You;Yipu Liu;Chuchu Ma;Jianpei Xu;Laozhi Xie;Shiqiang Tong;Yinzhe Sun;Fenfen Ma;Yukun Huang;Junbin Liu;Wenze Xiao;Chengxiang Dai;Suke Li;Jigang Lei;Qiyong Mei;Xiaoling Gao;Jun Chen
10 Biguanide-anchored albumin-based nanoplatform inhibits epithelial-mesenchymal transition and reduces the stemness phenotype for metastatic cancer therapy 期刊论文 Tianze Jiang;Jiahao Wang;Laozhi Xie;Songlei Zhou;Yukun Huang;Yu Chen;Xiaoling Gao;Wenze Xiao;Jun Chen
11 Vitality‐Enhanced Dual‐Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy 期刊论文 Xu Jianpei;Zhang Yuwen;Liu Yipu;You Yang;Li Fengan;Chen Yu;Xie Laozhi;Tong Shiqiang;Zhou Songlei;Liang Kaifan;Huang Yukun;Jiang Gan;Song Qingxiang;Mei Ni;Ma Fenfen;Gao Xiaoling;Wang He;Chen Jun
12 Tailored Apoptotic Vesicle Delivery Platform for Inflammatory Regulation and Tissue Repair to Ameliorate Ischemic Stroke 期刊论文 Yang You;Jianpei Xu;Yipu Liu;Haichun Li;Laozhi Xie;Chuchu Ma;Yinzhe Sun;Shiqiang Tong;Kaifan Liang;Songlei Zhou;Fenfen Ma;Qingxiang Song;Wenze Xiao;Kaikai Fu;Chengxiang Dai;Suke Li;Jigang Lei;Qiyong Mei;Xiaoling Gao;Jun Chen
13 Nano-Plumber Reshapes Glymphatic-Lymphatic System to Sustain Microenvironment Homeostasis and Improve Long-Term Prognosis after Traumatic Brain Injury 期刊论文 Tong Shiqiang;Xie Laozhi;Xie Xiaoying;Xu Jianpei;You Yang;Sun Yinzhe;Zhou Songlei;Ma Chuchu;Jiang Gan;Ma Fenfen;Wang Zhihua;Gao Xiaoling;Chen Jun
14 一种基于“全过程”调节理念的新型脂质体及其在创伤性脑损伤领域的应用 专利 陈钧;童世强
15 一种细胞活力增强的活体干细胞双模态纳米示踪系统及其制备方法 专利 陈钧;徐剑培
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享