| 1 |
Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors
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期刊论文 |
Wang, Bin|Gu, Lian-Quan|Huang, Zhi-Shu|Mai, Yi-Chi|Li, Yue|Hou, Jin-Qiang|Huang, Shi-Liang|Ou, Tian-Miao|Tan, Jia-Heng|An, Lin-Kun|Li, Ding| |
| 2 |
Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities
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期刊论文 |
An, Zeng-Yun|Yan, Yi-Yong|Peng, Dan|Ou, Tian-Miao|Tan, Jia-Heng|Huang, Shi-Liang|An, Lin-Kun|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 3 |
Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA
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期刊论文 |
Peng, Dan|Tan, Jia-Heng|Chen, Shuo-Bin|Ou, Tian-Miao|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 4 |
Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation
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期刊论文 |
Luo, Wen|Li, Yan-Ping|He, Yan|Huang, Shi-Liang|Tan, Jia-Heng|Ou, Tian-Miao|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 5 |
Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer';s disease
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期刊论文 |
Chen, Shang-Ying|Chen, Yuan|Li, Yan-Ping|Chen, Shu-Han|Tan, Jia-Heng|Ou, Tian-Miao|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 6 |
Quinolino-benzo-[5,6]-dihydroisoquindolium compounds derived from berberine: A new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene
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期刊论文 |
Ma, Yan|Ou, Tian-Miao|Tan, Jia-Heng|Hou, Jin-Qiang|Huang, Shi-Liang|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 7 |
Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase
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期刊论文 |
Li, Yue|Chen, Shu-Han|Ou, Tian-Miao|Tan, Jia-Heng|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 8 |
Syntheses and characterization of novel oxoisoaporphine derivatives as dual inhibitors for cholinesterases and amyloid beta aggregation
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期刊论文 |
Li, Yan-Ping|Gu, Lian-Quan|Huang, Zhi-Shu|Ning, Fang-Xian|Yang, Meng-Bi|Li, Yong-Cheng|Nie, Min-Hua|Ou, Tian-Miao|Tan, Jia-Heng|Huang, Shi-Liang|Li, Ding| |
| 9 |
Turning off Transcription of the bcl-2 Gene by Stabilizing the bcl-2 Promoter Quadruplex with Quindoline Derivatives.
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期刊论文 |
Wang|Z.|Xi|C.|Tan|J. H.|Huang|S. L.|An|L. K.|Li|X. D.|D.|Gu|L. Q.|Huang|Z. S.|Ou|T. M.|Lu|Y. J.|Li|Z.|Xu| |
| 10 |
Synthesis and biological evaluation of novel N,N '-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands.
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期刊论文 |
Luo|Z. S.|W.|Li|Y. P.|Tan|J. H.|Gu|L. Q.|Huang| |
| 11 |
Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand
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期刊论文 |
Chen, Shuo-Bin|Tan, Jia-Heng|Ou, Tian-Miao|Huang, Shi-Liang|An, Lin-Kun|Luo, Hai-Bin|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 12 |
Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA
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期刊论文 |
Wu, Wei-Bin|Chen, Shu-Han|Hou, Jin-Qiang|Tan, Jia-Heng|Ou, Tian-Miao|Huang, Shi-Liang|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 13 |
Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors
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期刊论文 |
Wu, Wei-Bin|Gu, Lian-Quan|Huang, Zhi-Shu|Ou, Jie-Bin|Huang, Zhi-Hong|Chen, Shuo-Bin|Ou, Tian-Miao|Tan, Jia-Heng|Li, Ding|Shen, Liu-Lan|Huang, Shi-Liang| |
| 14 |
Selective recognition of oncogene promoter G-quadruplexes by Mg2+
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期刊论文 |
Yan, Yi-Yong|Lin, Jing|Ou, Tian-Miao|Tan, Jia-Heng|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 15 |
Determination of SYUIQ-F5, a Novel Telomerase Inhibitor and Anti-tumor Lead-Compound, in Tissues and Plasma Samples by LC-MS-MS: Application to a Tissue Distribution Study in Rat.
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期刊论文 |
Xiong|G. P.|Ou|T. M.|Huang|Z. S.|H. Y.|Bi|H. C.|Wen|Y. G.|Hu|J. Q.|Zhong| |
| 16 |
New Insights into the Structures of Ligand-Quadruplex Complexes from Molecular Dynamics Simulations
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期刊论文 |
Hou, Jin-Qiang|Chen, Shuo-Bin|Tan, Jia-Heng|Ou, Tian-Miao|Luo, Hai-Bin|Li, Ding|Xu, Jun|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 17 |
Benzofuroquinoline Derivatives Had Remarkable Improvement of their Selectivity for Telomeric G-Quadruplex DNA over Duplex DNA upon Introduction of Peptidyl Group.
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期刊论文 |
Long|D.|Gu|L. Q.|Huang|Z. S.|Y.|Li|Z.|Tan|J. H.|Ou|T. M.|Li| |
| 18 |
Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents
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期刊论文 |
Luo, Wen|Li, Yan-Ping|He, Yan|Huang, Shi-Liang|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 19 |
Disubstituted 1,8-dipyrazolcarbazole derivatives as a new type of c-myc G-quadruplex binding ligands
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期刊论文 |
Chen, Wei-Jia|Zhou, Chen-Xi|Yao, Pei-Fen|Wang, Xiao-Xiao|Tan, Jia-Heng|Li, Ding|Ou, Tian-Miao|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 20 |
Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex
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期刊论文 |
Xu, Wei|Tan, Jia-Heng|Chen, Shuo-Bin|Hou, Jin-Qiang|Li, Ding|Huang, Zhi-Shu|Gu, Lian-Quan| |
| 21 |
A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones
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期刊论文 |
Wang, Bin|Li, Zeng|Wang, Xiao Ning|Tan, Jia Heng|Gu, Lian Quan|Huang, Zhi Shu| |
| 22 |
Impact of planarity of unfused aromatic molecules on G-quadruplex binding: Learning from isaindigotone derivatives
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期刊论文 |
Hou, Jin-Qiang|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu|Tan, Jia-Heng|Wang, Xiao-Xiao|Chen, Shuo-Bin|Huang, Si-Yuan|Yan, Jin-Wu|Chen, Shu-Han|Ou, Tian-Miao|Luo, Hai-Bin| |
| 23 |
Interaction of Berberine derivative with protein POT1 affect telomere function in cancer cells
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期刊论文 |
Xiao, Nannan|Chen, Siqi|Ma, Yan|Qiu, Jun|Tan, Jia-Heng|Ou, Tian-Miao|Gu, Lian-Quan|Huang, Zhi-Shu|Li, Ding| |
| 24 |
Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA
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期刊论文 |
Li, Zeng|Tan, Jia-Heng|He, Jin-Hui|Long, Yi|Ou, Tian-Miao|Li, Ding|Gu, Lian-Quan|Huang, Zhi-Shu| |
| 25 |
Effective Detection and Separation Method for G-Quadruplex DNA Based on Its Specific Precipitation with Mg2+.
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期刊论文 |
Lin|S. L.|Li|D.|Huang|Z. S.|Gu|L. Q.|J.|Yan|Y. Y.|Ou|T. M.|Tan|J. H.|Huang| |
| 26 |
Inhibition of Cell Proliferation by Quindoline Derivative (SYUIQ-05) through its Preferential Interaction with c-myc Promoter G-Quadruplex.
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期刊论文 |
Ou|J. H.|Chen|S. H.|Li|Z.|Li|Y. P.|Li|D.|Gu|T. M.|L. Q.|Huang|Z. S.|Lin|J.|Lu|Y. J.|Hou|J. Q.|Tan| |
