肠道菌群介导的胆汁酸代谢通过肠肝轴诱导NAFLD的病理机制探究
82000536
2020
H0307.肝脏代谢障碍及相关疾病
焦娜
青年科学基金项目
研究员
中山大学
24万元
多组学关联;非酒精性脂肪肝病;胆汁酸代谢;肠道菌群
2021-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD | 期刊论文 | Na Jiao;Rohit Loomba;Zi-Huan Yang;Dingfeng Wu;Sa Fang;Richele Bettencourt;Ping Lan;Ruixin Zhu;Lixin Zhu |
| 2 | Microbial genes outperform species and SNVs as diagnostic markers for Crohn’s disease on multicohort fecal metagenomes empowered by artificial intelligence | 期刊论文 | Sheng Gao;Xiang Gao;Ruixin Zhu;Dingfeng Wu;Zhongsheng Feng;Na Jiao;Ruicong Sun;Wenxing Gao;Qing He;Zhanju Liu;Lixin Zhu |
| 3 | Targeting keystone species helps restore the dysbiosis of butyrate‐producing bacteria in nonalcoholic fatty liver disease | 期刊论文 | Dingfeng Wu;Lei Liu;Na Jiao;Yida Zhang;Li Yang;Chuan Tian;Ping Lan;Lixin Zhu;Rohit Loomba;Ruixin Zhu |
| 4 | Multi-kingdom microbiota analyses identify bacterial-fungal interactions and biomarkers of colorectal cancer across cohorts | 期刊论文 | Ningning Liu;Na Jiao;Jing-Cong Tan;Ziliang Wang;Dingfeng Wu;An-Jun Wang;Jie Chen;Liwen Tao;Chenfen Zhou;Wenjie Fang;Io Hong Cheong;Weihua Pan;Wanqing Liao;Zisis Kozlakidis;Christopher Heeschen;Geromy G. Moore;Lixin Zhu;Xingdong Chen;Guoqing Zhang;Ruixin Zhu;Hui Wang |
| 5 | Identification of microbial markers across populations in early detection of colorectal cancer | 期刊论文 | Yuqi Wu;Na Jiao;Ruixin Zhu;Yida Zhang;Dingfeng Wu;An-Jun Wang;Sa Fang;Liwen Tao;Yichen Li;Sijing Cheng;Xiaosheng He;Ping Lan;Chuan Tian;Ning-Ning Liu;Lixin Zhu |
| 6 | NAFLDkb: A Knowledge Base and Platform for Drug Development against Nonalcoholic Fatty Liver Disease | 期刊论文 | Tingjun Xu;Wenxing Gao;Lixin Zhu;Wanning Chen;Chaoqun Niu;Wenjing Yin;Liangxiao Ma;Xinyue Zhu;Yunchao Ling;Sheng Gao;Lei Liu;Na Jiao;Weiming Chen;Guoqing Zhang;Ruixin Zhu;Dingfeng Wu |
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