新型萘内酰亚胺类PDE2抑制剂的设计、合成与抗肺动脉高压研究
82003652
2020
H3407.药物设计与药物信息
张晨
青年科学基金项目
讲师
中山大学
16万元
萘内酰亚胺;肺动脉高压;GA-FEP方法;共晶结构;磷酸二酯酶二型
2021-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors | 期刊论文 | Bei Zhang;Yue Huang;Si-Rui Zhang;Meng-Xing Huang;Chen Zhang;Hai-Bin Luo |
| 2 | Discovery of effective phosphodiesterase 2 inhibitors with antioxidant activities for the treatment of Alzheimer’s disease | 期刊论文 | Mei-Yan Jiang;Chuan Han;Chen Zhang;Qian Zhou;Bei Zhang;Mei-Ling Le;Meng-Xing Huang;Yinuo Wu;Hai-Bin Luo |
| 3 | Discovery of Dipyridamole Analogues with Enhanced Metabolic Stability for the Treatment of Idiopathic Pulmonary Fibrosis | 期刊论文 | Meng-Xing Huang;Yan-Quan Chen;Run-Duo Liu;Yue Huang;Chen Zhang |
| 4 | Design, Synthesis, and Evaluation of Dihydropyranopyrazole Derivatives as Novel PDE2 Inhibitors for the Treatment of Alzheimer's Disease | 期刊论文 | Yan Zhou;Jinjian Li;Han Yuan;Rui Su;Yue Huang;Yiyou Huang;Zhe Li;Yinuo Wu;Haibin Luo;Chen Zhang;Ling Huang |
查看更多信息请先登录或注册
