VIRMA介导CDK6 mRNA的m6A修饰增强其稳定性促进胰腺癌进展机制研究
82002505
2020
H1803.肿瘤细胞命运
李雅晴
青年科学基金项目
医师
中山大学
24万元
N6-甲基腺嘌呤;VIRMA;增殖与转移;胰腺外分泌肿瘤;纳米靶向干预
2021-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Arsenic Trioxide-loaded nanoparticles Enhance the Chemosensitivity of Gemcitabine in Pancreatic Cancer via Reversal of Pancreatic Stellate Cells Desmoplasia through Targeting AP4/Galectin-1 Pathway | 期刊论文 | Yue Zhao;Hanming Yao;Kege Yang;Shiji Han;Shangxiang Chen;Yaqing Li;Shaojie Chen;Kaihong Huang;Guoda Lian;Jiajia Li |
| 2 | GLUT1 Regulates the Tumor Immune Microenvironment and Promotes Tumor Metastasis in Pancreatic Adenocarcinoma via ncRNA-mediated Network | 期刊论文 | Fengjiao Li;Chong He;Hanming Yao;Weiling Liang;Xijiu Ye;Jianmin Ruan;Lijun Lin;Jinmao Zou;Shurui Zhou;Yuzhou Huang;Yaqing Li;Shaojie Chen;Kaihong Huang;Guoda Lian;Shangxiang Chen |
| 3 | A LETM2-Regulated PI3K-Akt Signaling Axis Reveals a Prognostic and Therapeutic Target in Pancreatic Cancer | 期刊论文 | Shurui Zhou;Ziyi Zhong;Yanzong Lu;Yunlong Li;Hanming Yao;Yue Zhao;Tairan Guo;Kege Yang;Yaqing Li;Shaojie Chen;Kaihong Huang;Guoda Lian |
| 4 | Glutamate from nerve cells promotes perineural invasion in pancreatic cancer by regulating tumor glycolysis through HK2 mRNA-m6A modification | 期刊论文 | Fengjiao Li;Chong He;Hanming Yao;Yue Zhao;Xijiu Ye;Shurui Zhou;Jinmao Zou;Yaqing Li;Jiajia Li;Shaojie Chen;Fanghai Han;Kaihong Huang;Guoda Lian;Shangxiang Chen |
| 5 | CCL3 secreted by hepatocytes promotes the metastasis of intrahepatic cholangiocarcinoma by VIRMA-mediated N6-methyladenosine (m6A) modification | 期刊论文 | Shurui Zhou;Kege Yang;Shaojie Chen;Guoda Lian;Yuzhou Huang;Hanming Yao;Yue Zhao;Kaihong Huang;Dong Yin;Haoming Lin;Yaqing Li |
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