miR-34a/SIRT1信号调控线粒体生成与线粒体自噬在老年性聋发病中的作用及机制研究

81873699
2018
H1404.听觉异常与平衡障碍
熊浩
面上项目
副主任医师
中山大学
57万元
内耳;老年性聋;治疗;毛细胞保护;发病机制
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 miR-34a/ATG9A/TFEB Signaling Modulates Autophagy in Cochlear Hair Cells and Correlates with Age-related Hearing Loss 期刊论文 Xiong Hao;Pang Jiaqi;Min Xin;Ye Yongyi;Lai Lan;Zheng Yiqing
2 Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis 期刊论文 Xiong Hao;Chen Suijun;Lai Lan;Yang Haidi;Xu Yaodong;Pang Jiaqi;Su Zhongwu;Lin Hanqing;Zheng Yiqing
3 SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy 期刊论文 Pang Jiaqi;Xiong Hao;Ou Yongkang;Yang Haidi;Xu Yaodong;Chen Suijun;Lai Lan;Ye Yongyi;Su Zhongwu;Lin Hanqing;Huang Qiuhong;Xu Xiaoding;Zheng Yiqing
4 Inhibition of DRP-1-Dependent Mitophagy Promotes Cochlea Hair Cell Senescence and Exacerbates Age-Related Hearing Loss 期刊论文 Lin Hanqing;Xiong Hao;Su Zhongwu;Pang Jiaqi;Lai Lan;Zhang Huasong;Jian Bingquan;Zhang Weijian;Zheng Yiqing
5 Glucose Protects Cochlear Hair Cells Against Oxidative Stress and Attenuates Noise-Induced Hearing Loss in Mice 期刊论文 Xiong Hao;Lai Lan;Ye Yongyi;Zheng Yiqing
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