长效白细胞介素22治疗糖尿病肾病的作用及机制研究
81773620
2017
H3404.生物技术药物
鞠佃文
面上项目
教授
复旦大学
48万元
白细胞介素22;炎性小体;糖尿病肾病;细胞自噬;XTEN技术
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Interleukin-22 ameliorated acetaminophen-induced kidney injury by inhibiting mitochondrial dysfunction and inflammatory responses | 期刊论文 | Shen Yilan;Jin Xin;Chen Wei;Gao Congrong;Bian Qi;Fan Jiajun;Luan Jingyun;Cao Zhonglian;Guo Zhiyong;Gu Yuting;Liu Hongrui;Ju Dianwen;Mei Xiaobin |
| 2 | NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1 beta Accelerated ConA-Induced Hepatitis | 期刊论文 | Luan Jingyun;Zhang Xuyao;Wang Shaofei;Li Yubin;Fan Jiajun;Chen Wei;Zai Wenjing;Wang Sijia;Wang Yichen;Chen Mingkuan;Meng Guangxun;Ju Dianwen |
| 3 | Inflammasome: A Double-Edged Sword in Liver Diseases | 期刊论文 | Jingyun Luan;Dianwen Ju |
| 4 | In vivo hepatocellular expression of interleukin-22 using penetratin-based hybrid nanoparticles as potential anti-hepatitis therapeutics | 期刊论文 | Chen Wei;Luan Jingyun;Wei Gang;Zhang Xuyao;Fan Jiajun;Zai Wenjing;Wang Shaofei;Wang Yichen;Liang Yanxu;Nan Yanyang;Yin Chuzhen;Li Yubin;Liu Ming-lin;Ju Dianwen |
| 5 | Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome | 期刊论文 | Ding Tao;Wang Shaofei;Zhang Xuyao;Zai Wenjing;Fan Jiajun;Chen Wei;Bian Qi;Luan Jingyun;Shen Yilan;Zhang Yanda;Ju Dianwen;Mei Xiaobin |
| 6 | VEGF-B antibody and interleukin-22 fusion protein ameliorates diabetic nephropathy through inhibiting lipid accumulation and inflammatory responses | 期刊论文 | Shen Yilan;Chen Wei;Han Lei;Bian Qi;Fan Jiajun;Cao Zhonglian;Jin Xin;Ding Tao;Xian Zongshu;Guo Zhiyong;Zhang Wei;Ju Dianwen;Mei Xiaobin |
| 7 | Interleukin-22 Attenuated Renal Tubular Injury in Aristolochic Acid Nephropathy via Suppressing Activation of NLRP3 Inflammasome | 期刊论文 | Wang Shaofei;Fan Jiajun;Mei Xiaobin;Luan Jingyun;Li Yubin;Zhang Xuyao;Chen Wei;Wang Yichen;Meng Guangxun;Ju Dianwen |
| 8 | Tethering Interleukin-22 to Apolipoprotein A-I Ameliorates Mice from Acetaminophen-induced Liver Injury | 期刊论文 | Chen Wei;Zhang Xuyao;Fan Jiajun;Zai Wenjing;Luan Jingyun;Li Yubin;Wang Shaofei;Chen Qicheng;Wang Yichen;Liang Yanxu;Ju Dianwen |
| 9 | Targeted Interleukin-22 Gene Delivery in the Liver by Polymetformin and Penetratin-Based Hybrid Nanoparticles to Treat Nonalcoholic Fatty Liver Disease | 期刊论文 | Zai Wenjing;Chen Wei;Wu Zimei;Jin Xin;Fan Jiajun;Zhang Xuyao;Luan Jingyun;Tang Shijie;Mei Xiaobin;Hao Bang;Liu Hongrui;Ju Dianwen |
| 10 | Therapeutic Opportunities of IL-22 in Non-Alcoholic Fatty Liver Disease: From Molecular Mechanisms to Clinical Applications | 期刊论文 | 鞠佃文 |
| 11 | GSDMD membrane pore is critical for IL-1 beta release and antagonizing IL-1 beta by hepatocyte-specific nanobiologics is a promising therapeutics for murine alcoholic steatohepatitis | 期刊论文 | Luan Jingyun;Chen Wei;Fan Jiajun;Wang Shaofei;Zhang Xuyao;Zai Wenjing;Jin Xin;Wang Yichen;Feng Zhenyi;Zhang Jinghui;Liu Ming-Lin;Ju Dianwen |
| 12 | Gene therapy for neurodegenerative disorders: advances, insights and prospects | 期刊论文 | Wei Chen;Yang Hu;Dianwen Ju |
| 13 | IL-22-mediated renal metabolic reprogramming via PFKFB3 to treat kidney injury | 期刊论文 | Chen Wei;Shen Yilan;Fan Jiajun;Zeng Xian;Zhang Xuyao;Luan Jingyun;Wang Yichen;Zhang Jinghui;Fang Si;Mei Xiaobin;Zhao Zhen;Ju Dianwen |
| 14 | Mesoporous silica nanoparticles induced hepatotoxicity via NLRP3 inflammasome activation and caspase-1-dependent pyroptosis | 期刊论文 | Zhang Xuyao;Luan Jingyun;Chen Wei;Fan Jiajun;Nan Yanyang;Wang Yichen;Liang Yanxu;Meng Guangxun;Ju Dianwen |
| 15 | Large-scale microcarrier culture of HEK293T cells and Vero cells in single-use bioreactors | 期刊论文 | Yang Jianjun;Guertin Patrick;Jia Guodong;Lv Zhongliang;Yang Hongyan;Ju Dianwen |
| 16 | Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury | 期刊论文 | Chen Wei;Zai Wenjing;Fan Jiajun;Zhang Xuyao;Zeng Xian;Luan Jingyun;Wang Yichen;Shen Yilan;Wang Ziyu;Dai Shixuan;Fang Si;Zhao Zhen;Ju Dianwen |
| 17 | A Novel Bifunctional Fusion Protein, Vunakizumab-IL22, for Protection Against Pulmonary Immune Injury Caused by Influenza Virus | 期刊论文 | Han Lei;Shi Chenchen;Zeng Xian;Cen Lifeng;Mei Xiaobin;Fan Jiajun;Ju Dianwen;Zhu Haiyan |
查看更多信息请先登录或注册
