Caspase-11剪切GsdmD在促进急性肾损伤时肾小管上皮细胞释放白细胞介素-18中的作用及机制研究
81873603
2018
H0502.泌尿系统损伤与修复
陆利民
面上项目
教授
复旦大学
57万元
炎症反应;caspase-11;缺血-再灌注;肾小管上皮细胞;急性肾损伤
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax | 期刊论文 | Li JY;Sun XA;Yang NH;Ni JY;Xie HY;Guo HJ;Wang X;Zhou L;Liu J;Chen SJ;Wang XX;Zhang YY;Yu C;Zhang W;Lu LM（陆利民） |
| 2 | Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II | 期刊论文 | Ni JY;Wang X;Xie HY;Yang NH;Li JY;Sun XA;Guo HJ;Zhou L;Zhang W;Liu J;Lu LM（陆利民） |
| 3 | Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy | 期刊论文 | Cheng Qian;Pan Jing;Zhou Zhuanli;Yin Fan;Xie Hongyan;Chen Panpan;Li Jingyao;Zheng Peiqing;Zhou Li;Zhang Wei;Liu Jun;Lu Limin （陆利民） |
| 4 | FoxM1 promotes Wnt/beta-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions | 期刊论文 | Xie Hongyan;Miao Naijun;Xu Dan;Zhou Zhuanli;Ni Jiayun;Yin Fan;Wang Yanzhe;Cheng Qian;Chen Panpan;Li Jingyao;Zheng Peiqing;Zhou Li;Liu Jun;Zhang Wei;Wang Xiaoxia;Lu Limin （陆利民） |
| 5 | The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury | 期刊论文 | Miao Naijun;Yin Fan;Xie Hongyan;Wang Yanzhe;Xu Yiang;Shen Yang;Xu Dan;Yin Jianyong;Wang Bao;Zhou Zhuanli;Cheng Qian;Chen Panpan;Xue Hong;Zhou Li;Liu Jun;Wang Xiaoxia;Zhang Wei;Lu Limin（陆利民） |
| 6 | Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin 1 in acute kidney disease | 期刊论文 | Yin F;Zheng PQ;Zhao LQ;Wang YZ;Miao NJ;Zhou ZL;Cheng Q;Chen PP;Xie HY;Li JY;Ni JY;Zhou L;Zhang W;Wang XX;Liu J;Lu LM （陆利民） |
| 7 | RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice | 期刊论文 | Zhou Zhuanli;Ni Jiayun;Li Jingyao;Huo Chuanbing;Miao Naijun;Yin Fan;Cheng Qian;Xu Dan;Xie Hongyan;Chen Panpan;Zheng Peiqing;Zhang Yingying;Zhou Li;Zhang Wei;Yu Chen;Liu Jun;Lu Limin （陆利民） |
| 8 | 调节性细胞死亡与急性肾损伤 | 期刊论文 | 倪佳云;陆利民 |
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