GOLM1/TLR9途径调节自噬促进肝癌恶性潜能的机制研究
81871924
2018
H1807.肿瘤代谢
叶青海
面上项目
教授
复旦大学
57万元
肿瘤转移;TLR9;GOLM1;自噬;肝和肝内胆管肿瘤
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | GOLM1 upregulates expression of PD-L1 through EGFR/STAT3 pathway in hepatocellular carcinoma | 期刊论文 | Yan Jiuliang;Zhou Binghai;Guo Lei;Chen Zheng;Zhang Bo;Liu Shuang;Zhang Wentao;Yu Mincheng;Xu Yongfeng;Xiao Yongsheng;Zhou Jian;Fan Jia;Li Hui;Ye Qinghai |
| 2 | Association of intrinsic pathways with altered tumor immune infiltration in hepatocellular carcinoma: New targets for combining immune therapy | 期刊论文 | Zheng Chen;Mincheng Yu;Jiuliang Yan;Binghai Zhou;Wentao Zhang;Lei Guo;Bo Zhang;Shuang Liu;Lei Jin;Jian Zhou;Jia Fan;Qing-Hai Ye;Hui Li;Yong-Sheng Xiao;Yongfeng Xu |
| 3 | Complement C5 is a novel biomarker for liver metastasis of colorectal cancer | 期刊论文 | Hulin Chang;Lei Jin;Peiyi Xie;Bo Zhang;Mincheng Yu;Hui Li;Shuang Liu;Jiuliang Yan;Binghai Zhou;Xiaoqiang Li;Yongfeng Xu;Yongsheng Xiao;Qinghai Ye;Lei Guo |
| 4 | Recent advances of GOLM1 in hepatocellular carcinoma | 期刊论文 | Jiuliang Yan;Binghai Zhou;Hui Li;Lei Guo;Qing-Hai Ye |
| 5 | Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma | 期刊论文 | Binghai Zhou;Jiuliang Yan;Lei Guo;Bo Zhang;Shuang Liu;Mincheng Yu;Zheng Chen;Kewei Zhang;Wentao Zhang;Xiaoqiang Li;Yongfeng Xu;Yong-Sheng Xiao;Jian Zhou;Jia Fan;Mien Chie Hung;Hui Li;Qing-Hai Ye |
| 6 | High serum gamma-glutamyl transpeptidase concentration associates with poor postoperative prognosis of patients with hepatitis B virus-associated intrahepatic cholangiocarcinoma. | 期刊论文 | Zhang Bo;Liu Shuang;Zhou Binghai;Guo Lei;Li Hui;Yan Jiuliang;Zhang Wentao;Yu Mincheng;Chen Zheng;Xu Yongfeng;Xiao Yongsheng;Ye Qinghai |
| 7 | KDM5C Represses FASN-Mediated Lipid Metabolism to Exert Tumor Suppressor Activity in Intrahepatic Cholangiocarcinoma | 期刊论文 | Bo Zhang;Bing-hai Zhou;Min Xiao;Hui Li;Lei Guo;Meng-xi Wang;Shan-he Yu;Qing-hai Ye |
| 8 | PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology | 期刊论文 | Chen Zheng;Yu Mincheng;Yan Jiuliang;Guo Lei;Zhang Bo;Liu Shuang;Lei Jin;Zhang Wentao;Zhou Binghai;Gao Jie;Yang Zhangfu;Li Xiaoqiang;Zhou Jian;Fan Jia;Ye Qinghai;Li Hui;Xu Yongfeng;Xiao Yongsheng |
| 9 | Case report: immunotherapy successfully treated brain metastasis in intrahepatic cholangiocarcinoma and literature review | 期刊论文 | Peiyi Xie;Lei Guo;Bo Zhang;Yongfeng Xu;Qi Song;Hongcheng Shi;Qinghai Ye;Hui Li;Yongsheng Xiao |
| 10 | PARG inhibition limits HCC progression and potentiates the efficacy of immune checkpoint therapy | 期刊论文 | Mincheng Yu;Zheng Chen;Qiang Zhou;Bo Zhang;Jinlong Huang;Lei Jin;Binghai Zhou;Shuang Liu;Jiuliang Yan;Xiaoqiang Li;Wentao Zhang;Chunxiao Liu;Bo Hu;Peiyao Fu;Chenhao Zhou;Yongfeng Xu;Yongsheng Xiao;Jian Zhou;Jia Fan;Ning Ren;Mien-Chie Hung;Lei Guo;Hui Li;Qinghai Ye |
| 11 | Tumor-derived PD1 and PD-L1 could promote hepatocellular carcinoma growth through autophagy induction in vitro | 期刊论文 | Zheng Chen;Shuang Liu;Peiyi Xie;Bo Zhang;Mincheng Yu;Jiuliang Yan;Lei Jin;Wentao Zhang;Binghai Zhou;Xiaoqiang Li;Yongsheng Xiao;Yongfeng Xu;Qinghai Ye;Hui Li;Lei Guo |
| 12 | CD44 potentiates hepatocellular carcinoma migration and extrahepatic metastases via the AKT/ERK signaling CXCR4 axis | 期刊论文 | Peiyi Xie;Jiuliang Yan;Mengyuan Wu;Hui Li;Zheng Chen;Mincheng Yu;Bo Zhang;Lingli Chen;Lei Jin;Binghai Zhou;Xiaoqiang Li;Yongsheng Xiao;Yongfeng Xu;Jiang Long;Jubo Zhang;Lei Guo |
| 13 | Tumor Derived SIGLEC Family Genes May Play Roles in Tumor Genesis, Progression, and Immune Microenvironment Regulation | 期刊论文 | Chen Zheng;Yu Mincheng;Guo Lei;Zhang Bo;Liu Shuang;Zhang Wentao;Zhou Binghai;Yan Jjiuliang;Ma Qianni;Yang Zhangfu;Xiao Yongsheng;Xu Yongfeng;Li Hui;Ye Qinghai |
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