TLR4/p300通路介导的MAP4K4表观遗传修饰在糖尿病视网膜病变中的作用及机制研究

81870670
2018
H1305.视网膜、脉络膜及玻璃体相关疾病
常青
面上项目
主任医师
复旦大学
57万元
新生血管生成;糖尿病视网膜病变;糖尿病黄斑水肿;丝裂原活化蛋白激酶4;表观遗传修饰
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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1 PKM2 Is a Potential Diagnostic and Therapeutic Target for Retinitis Pigmentosa 期刊论文 Peiwen Zhu;Qian Yang;Gang Li;Qing Chang
2 Threshold thickness of foveal outer nuclear layer associated with outcomes of photodynamic therapy in central serous chorioretinopathy 期刊论文 Jia Yu;Xiaofeng Ye;Lei Li;Chunhui Jiang;Qing Chang;Gezhi Xu
3 Three Monthly Injections Versus One Initial Injection of Ranibizumab for the Treatment of Macular Edema Secondary to Branch Retinal Vein Occlusion: 12-Month Results of a Prospective Randomized Study 期刊论文 Wenyi Tang;Jingli Guo;Gezhi Xu;Wei Liu;Qing Chang
4 Perivascular Flower-Bud-like Lesions on En Face Optical Coherence Tomography Angiography in Patients with Vitreoretinal Lymphoma 期刊论文 Wenwen Chen;Junxiang Gu;Shixue Liu;Zhenyang Zhao;Tingting Jiang;Gezhi Xu;Qing Chang
5 ABCA4 Gene Screening in a Chinese Cohort With Stargardt Disease: Identification of 37 Novel Variants 期刊论文 Fang-Yuan Hu;Jian-kang Li;Feng-Juan Gao;Yu-He Qi;Ping Xu;Yong-Jin Zhang;Dan-Dan Wang;Lu-Sheng Wang;Wei Li;Min Wang;Fang Chen;Si-Mai Shen;Ge-Zhi Xu;Sheng-Hai Zhang;Qing Chang;Ji-Hong Wu
6 A Novel Approach to Quantitative Evaluation of Outer Retinal Lesions Via a New Parameter "Integral" in Spectral Domain Optical Coherence Tomography 期刊论文 Gu Junxiang;Jiang Tingting;Yu Mingrong;Yu Jian;Li Wenting;Liu Shixue;Zhang Peijun;Chen Wenwen;Chang Qing
7 CLINICAL FEATURES, DIAGNOSTIC SIGNIFICANCE, AND PROGNOSIS OF VITREORETINAL LYMPHOMA IN YOUNG PATIENTS 期刊论文 Shixue Liu;Junxiang Gu;Ting Zhang;Bo Ping;Min Zhou;Xin Huang;Rui Jiang;Gezhi Xu;Qing Chang
8 Retinal changes of primary vitreoretinal lymphoma after intravitreal methotrexate 期刊论文 Tingting Jiang;Junxiang Gu;Shixue Liu;Qing Chang
9 Prognosis of Ocular Tuberculosis Following Long-Term Antitubercular Therapy 期刊论文 Tingting Jiang;Xiaozhe Zhang;Min Zhou;Rui Jiang;Qing Chang
10 Cell-Free DNA Sequencing of Intraocular Fluid as Liquid Biopsy in the Diagnosis of Vitreoretinal Lymphoma 期刊论文 Junxiang Gu;Tingting Jiang;Shixue Liu;Bo Ping;Ruiwen Li;Wenwen Chen;Ling Wang;Xin Huang;Gezhi Xu;Qing Chang
11 Genotypic spectrum and phenotype correlations of EYS-associated disease in a Chinese cohort 期刊论文 Feng-Juan Gao;Dan-Dan Wang;Fang-Yuan Hu;Ping Xu;Qing Chang;Jian-Kang Li;Wei Liu;Sheng-Hai Zhang;Ge-Zhi Xu;Ji-Hong Wu
12 Role of TLR4-MAP4K4 signaling pathway in models of oxygen-induced retinopathy 期刊论文 Chen Wenwen;Zhang Juan;Zhang Peijun;Hu Fangyuan;Jiang Tingting;Gu Junxiang;Chang Qing
13 Resveratrol inhibits high-glucose-induced inflammatory “metabolic memory” in human retinal vascular endothelial cells through SIRT1-dependent signaling 期刊论文 Tingting Jiang;Junxiang Gu;Wenwen Chen;Qing Chang
14 Clinical Characteristics of Pregnancy-Associated Central Serous Chorioretinopathy in the Chinese Population 期刊论文 Jia Yu;Lei Li;Chunhui Jiang;Qing Chang;Gezhi Xu
15 The effect of adjunctive intravitreal conbercept at the end of diabetic vitrectomy for the prevention of post-vitrectomy hemorrhage in patients with severe proliferative diabetic retinopathy: a prospective, randomized pilot study 期刊论文 Jiang Tingting;Gu Junxiang;Zhang Peijun;Chen Wenwen;Chang Qing
16 Protective effects of rapamycin on the retinal vascular bed during the vaso‐obliteration phase in mouse oxygen‐induced retinopathy model 期刊论文 Juan Zhang;Min Zhu;Lu Ruan;Chen Jiang;Qian Yang;Qing Chang;Xin Huang
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