NLRP3炎症小体在大气细颗粒物促发2型糖尿病中的作用机制
81673125
2016
H3001.环境卫生
赵金镯
面上项目
教授
复旦大学
65万元
免疫损伤;炎症反应;细颗粒物;2型糖尿病;NLRP3炎症小体
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites | 期刊论文 | Du Xihao;Zeng Xuejiao;Zhang Jia;Pan Kun;Song Liying;Zhou Ji;Zhou Li;Xie Yuquan;Sun Qinghua;Ge Wenzhen;Chen Renjie;Zhao Jinzhuo;Kan Haidong |
| 2 | The severity of lung injury and metabolic disorders induced by ambient PM2.5 exposure is associated with cumulative dose | 期刊论文 | Jiang Shuo;Zhou Ji;Zhang Jia;Du Xihao;Zeng Xuejiao;Pan Kun;Xie Yuquan;Kan Haidong;Sun Qinghua;Cai Jing;Zhao Jinzhuo |
| 3 | AMPK activation attenuates inflammatory response to reduce ambient PM2.5-induced metabolic disorders in healthy and diabetic mice | 期刊论文 | Pan Kun;Jiang Shuo;Du Xihao;Zeng Xuejiao;Zhang Jia;Song Liying;Zhou Ji;Kan Haidong;Sun Qinghua;Xie Yuquan;Zhao Jinzhuo |
| 4 | The essential function of CARD9 in diet-induced inflammation and metabolic disorders in mice | 期刊论文 | Zeng Xuejiao;Du Xihao;Zhang Jia;Jiang Shuo;Liu Jie;Xie Yuquan;Shan Wei;He Guanglong;Sun Qinghua;Zhao Jinzhuo |
| 5 | 运动对大气颗粒物所致健康危害的干预研究进展 | 期刊论文 | 潘坤;赵金镯 |
| 6 | Parental PM2.5 Exposure-Promoted Development of Metabolic Syndrome in Offspring Is Associated With the Changes of Immune Microenvironment | 期刊论文 | Zhang Jia;Zeng Xuejiao;Du Xihao;Pan Kun;Song Liying;Song Weimin;Xie Yuquan;Zhao Jinzhuo |
| 7 | Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE(-/-) mice | 期刊论文 | Du Xihao;Jiang Shuo;Zeng Xuejiao;Zhang Jia;Pan Kun;Zhou Ji;Xie Yuquan;Kan Haidong;Song Weimin;Sun Qinghua;Zhao Jinzhuo |
| 8 | AMPK activation ameliorates fine particulate matter-induced hepatic injury | 期刊论文 | Song Liying;Jiang Shuo;Pan Kun;Du Xihao;Zeng Xuejiao;Zhang Jia;Zhou Ji;Sun Qinghua;Xie Yuquan;Zhao Jinzhuo |
| 9 | Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E-/- mice | 期刊论文 | Du Xihao;Jiang Shuo;Zeng Xuejiao;Zhang Jia;Pan Kun;Song Liying;Zhou Ji;Kan Haidong;Sun Qinghua;Zhao Jinzhuo;Xie Yuquan |
| 10 | 运动对PM_(2.5)所致小鼠细胞免疫功能改变的影响 | 期刊论文 | 潘坤;赵金镯 |
| 11 | Metabolomics analysis of urine from healthy wild type mice exposed to ambient PM2.5 | 期刊论文 | Du Xihao;Zeng Xuejiao;Pan Kun;Zhang Jia;Song Liying;Zhou Ji;Chen Renjie;Xie Yuquan;Sun Qinghua;Zhao Jinzhuo;Kan Haidong |
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