Wnt4/Fzd10/LRP6-NLK信号轴调控炎症微环境促进强直性脊柱炎异位成骨的机制研究
81772307
2017
H0602.运动系统免疫相关疾病
刘辉
面上项目
主任医师
中山大学
55万元
Wnt蛋白;肿瘤坏死因子-α;成骨;炎症微环境;强直性脊柱炎
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis | 期刊论文 | Li Xiang;Chen Siwen;Hu Zaiying;Chen Dongying;Wang Jianru;Li Zemin;Li Zihao;Cui Haowen;Dai Guo;Liu Lei;Wang Haitao;Zhang Kuibo;Zheng Zhaomin;Zhan Zhongping;Liu Hui |
| 2 | Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis | 期刊论文 | Zihao Li;Siwen Chen;Haowen Cui;Xiang Li;Dongying Chen;Wenjun Hao;Jianru Wang;Zemin Li;Zhaomin Zheng;Zhongping Zhang;Hui Liu |
| 3 | BRD4 promotes heterotopic ossification through upregulation of LncRNA MANCR. | 期刊论文 | Liu Lei;Li ZiHao;Chen Siwen;Cui Haowen;Li Xiang;Dai Guo;Zhong Fangling;Hao Wenjun;Zhang Kuibo;Liu Hui |
| 4 | LncRNA HOTTIP enhances human osteogenic BMSCs differentiation via interaction with WDR5 and activation of Wnt/beta-catenin signalling pathway | 期刊论文 | Liu Ruiduan;Li Zihao;Song Enhong;Hu Panyong;Yang Qinghua;Hu Yiwen;Liu Hui;Jin Anmin |
| 5 | Wnt4 signaling mediates protective effects of melatonin on new bone formation in an inflammatory environment | 期刊论文 | Li Xiang;Li Zihao;Wang Jianru;Li Zemin;Cui Haowen;Dai Guo;Chen Siwen;Zhang Mingliang;Zheng Zhaomin;Zhan Zhongping;Liu Hui |
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