利用端粒DSB激活ALT通路及其分子机制研究
81771506
2017
H1901.衰老机制与调控
刘海英
面上项目
副教授
中山大学
54万元
信号通路;端粒结构;端粒;表观遗传学;端粒延伸替代机制
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | TERC promotes cellular inflammatory response independent of telomerase | 期刊论文 | Liu Haiying;Yang Yiding;Ge Yuanlong;Liu Juanhong;Zhao Yong |
| 2 | 2D gel electrophoresis reveals dynamics of t-loop formation during the cell cycle and t-loop in maintenance regulated by heterochromatin state | 期刊论文 | Zhang Zepeng;Zhang Tianpeng;Ge Yuanlong;Tang Mengfan;Ma Wenbin;Zhang Qinfen;Gong Shengzhao;Wright Woodring E.;Shay Jerry;Liu Haiying;Zhao Yong |
| 3 | RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability | 期刊论文 | Zheng Tian;Zhou Haoxian;Li Xiaocui;Peng Di;Yang Yiding;Zeng Yanru;Liu Haiying;Ren Jian;Zhao Yong |
| 4 | Telomeric Recombination Inducer by DNA Damage Results in Telomere Extension and Length Heterogeneity | 期刊论文 | Liu Haiying;Xie Yujie;Zhang Zepeng;Mao Pingsu;Liu Jingfan;Ma Wenbin;Zhao Yong |
| 5 | Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination | 期刊论文 | Zhang Tianpeng;Zhang Zepeng;Gong Shengzhao;Li Xiaocui;Liu Haiying;Zhao Yong |
| 6 | SARS-CoV-2入侵细胞相关分子结构与机制的研究进展 | 期刊论文 | 李沛霖;刘海英 |
| 7 | TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication | 期刊论文 | Nie Xin;Xiao Danqing;Ge Yuanlong;Xie Yujie;Zhou Haoxian;Zheng Tian;Li Xiaocui;Liu Haiying;Huang Hui;Zhao Yong |
| 8 | cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence | 期刊论文 | Li Xiaocui;Li Xiaojuan;Xie Chen;Cai Sihui;Li Mengqiu;Jin Heping;Wu Shu;Cui Jun;Liu Haiying;Zhao Yong |
| 9 | Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers | 期刊论文 | Ge Yuanlong;Wu Shu;Zhang Zepeng;Li Xiaocui;Li Feng;Yen Siyu;Liu Haiying;Huang Junjiu;Zhao Yong |
| 10 | LIN28/let-7/PD-L1 Pathway as a Target for Cancer Immunotherapy | 期刊论文 | Chen Yanlian;Xie Chen;Zheng Xiaohui;Nie Xin;Wang Zining;Liu Haiying;Zhao Yong |
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