PDSS2新的转录变异体PDSS2-D2促进肝癌细胞播散和干性增强及分子机制研究

81871903
2018
H1804.肿瘤遗传与进化
李焱
面上项目
研究员
中山大学
57万元
肿瘤转移;肿瘤干性;异戊烯二磷酸合成酶亚基2;肝和肝内胆管肿瘤;转录变异体
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression 期刊论文 Li Lei;Wei Jia-Ru;Song Ye;Fang Shuo;Du Yanyu;Li Zhuo;Zeng Ting-Ting;Zhu Ying-Hui;Li Yan;Guan Xin-Yuan
2 PDSS2-Del2, a new variant of PDSS2, promotes tumor cell metastasis and angiogenesis in hepatocellular carcinoma via activating NF-κB 期刊论文 Zeng T;Tang Z;Liang L;Suo D;Li L;Li J;Yuan Y;Guan XY;Li Y
3 NRIP3 upregulation confers resistance to chemoradiotherapy in ESCC via RTF2 removal by accelerating ubiquitination and degradation of RTF2 期刊论文 Suo D;Wang L;Zeng T;Zhang H;Li L;Liu J;Yun J;Guan XY;Li Y
4 Membrane Metalloendopeptidase (MME) Suppresses Metastasis of Esophageal Squamous Cell Carcinoma (ESCC) by Inhibiting FAK-RhoA Signaling Axis 期刊论文 Mengqing Li;Ling Wang;Yuting Zhan;Tingting Zeng;Xu Zhang;Xin-Yuan Guan;Yan Li
5 Laminin gamma 2-mediating T cell exclusion attenuates response to anti-PD-1 therapy 期刊论文 Li Lei;Wei Jia-Ru;Dong Jun;Lin Qing-Guang;Tang Hong;Jia Yong-Xu;Tan Wanlin;Chen Qing-Yun;Zeng Ting-Ting;Xing Shan;Qin Yan-Ru;Zhu Ying-Hui;Li Yan;Guan Xin-Yuan
6 HOXC10 upregulation confers resistance to chemoradiotherapy in ESCC tumor cells and predicts poor prognosis. 期刊论文 Suo D;Wang Z;Li L;Chen Q;Zeng T;Liu R;Yun J;Guan XY;Li Y
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