赖氨酸同型半胱氨酸修饰促新发突变致先天性心脏病的分子机理
81771627
2017
H0421.新生儿相关疾病
赵健元
面上项目
研究员
复旦大学
50万元
叶酸代谢通路;DNA损伤修复;新发突变;赖氨酸同型半胱氨酸修饰;先天性心脏病
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects | 期刊论文 | Mei Xinyu;Qi Dashi;Zhang Ting;Zhao Ying;Jin Li;Hou Junli;Wang Jianhua;Lin Yan;Xue Yu;Zhu Pingping;Liu Zexian;Huang Lei;Nie Ji;Si Wen;Ma Jingyi;Ye Jianhong;Finnell Richard H.;Saiyin Hexige;Wang Hongyan;Zhao Jianyuan;Zhao Shimin;Xu Wei |
| 2 | APC/C-CDH1 synchronizes ribose-5-phosphate levels and DNA synthesis to cell cycle progression | 期刊论文 | Li Yang;Yao Cui-Fang;Xu Fu-Jiang;Qu Yuan-Yuan;Li Jia-Tao;Lin Yan;Cao Zhong-Lian;Lin Peng-Cheng;Xu Wei;Zhao Shi-Min;Zhao Jian-Yuan |
| 3 | Inactivation of the AMPK-GATA3-ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth | 期刊论文 | Qu Yuan-Yuan;Zhao Rui;Zhang Hai-Liang;Zhou Qian;Xu Fu-Jiang;Zhang Xuan;Xu Wen-Hao;Shao Ning;Zhou Shu-Xian;Dai Bo;Zhu Yao;Shi Guo-Hai;Shen Yi-Jun;Zhu Yi-Ping;Han Cheng-Tao;Chang Kun;Lin Yan;Zang Wei-Dong;Xu Wei;Ye Ding-Wei;Zhao Shi-Min;Zhao Jian-Yuan |
| 4 | Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. | 期刊论文 | Xu Sha;Tao Hui;Cao Wei;Cao Li;Lin Yan;Zhao Shi-Min;Xu Wei;Cao Jing;Zhao Jian-Yuan |
| 5 | Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk | 期刊论文 | Wang Xiao-Hui;Xu Sha;Zhou Xiang-Yu;Zhao Rui;Lin Yan;Cao Jing;Zang Wei-Dong;Tao Hui;Xu Wei;Li Ming-Qing;Zhao Shi-Min;Jin Li-Ping;Zhao Jian-Yuan |
| 6 | Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair | 期刊论文 | Wang Dan;Zhao Rui;Qu Yuan-Yuan;Mei Xin-Yu;Zhang Xuan;Zhou Qian;Li Yang;Yang Shao-Bo;Zuo Zhi-Gui;Chen Yi-Ming;Lin Yan;Xu Wei;Chen Chao;Zhao Shi-Min;Zhao Jian-Yuan |
| 7 | Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation | 期刊论文 | Zhang Xuan;Qu Yuan-Yuan;Liu Lian;Qiao Ya-Nan;Geng Hao-Ran;Lin Yan;Xu Wei;Cao Jing;Zhao Jian-Yuan |
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