氧化低密度脂蛋白及其受体在高血压导致心肌线粒体损伤中的作用机制和干预研究
81730009
2017
H02.循环系统
邹云增
重点项目
教授
复旦大学
295万元
分子机制;线粒体;心肌细胞损伤;高血压;氧化低密度脂蛋白
2018-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Caspase-1 abrogates the salutary effects of hypertrophic preconditioning in pressure overload hearts via IL-1β and IL-18 | 期刊论文 | Dai F（）;Li X（）;Li X（）;Ding Z;Xu R;Yin P;Wang S;Ge J;Wu J（✱）;Zou Y（✱） |
| 2 | Identification of Differential Expression Genes between Volume and Pressure Overloaded Hearts Based on Bioinformatics Analysis | 期刊论文 | Yuanfeng Fu;Di Zhao;Yufei Zhou;Jing Lu;Le Kang;Xueli Jiang;Ran Xu;Zhiwen Ding;Yunzeng Zou |
| 3 | Low density lipoprotein receptor related protein 6 (LRP6) protects heart against oxidative stress by the crosstalk of HSF1 and GSK3β | 期刊论文 | Wang Ying;Chen Zhidan;Li Yang;Ma Leilei;Zou Yan;Wang Xiang;Yin Chao;Pn Le;Shen Yi;Jia Jianguo;Yuan Jie;Zhang Guoping;Yang Chunjie;Ge Junbo;Zou Yunzeng;Gong Hui |
| 4 | Gender Differences in Cardiac Hypertrophy | 期刊论文 | Jian Wu;Fangjie Dai;Chang Li;Yunzeng Zou |
| 5 | CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b | 期刊论文 | Shijun Wang;Jian Wu;Xuan Li;Rubin Tan;Liming Chen;Lifan Yang;Fangjie Dai;Leilei Ma;Lei Xu;Zhen Wang;Gang Zhao;Junbo Ge;Yunzeng Zou |
| 6 | Inverse Associations Between Circulating Secreted Frizzled Related Protein 2 (sFRP2) and Cardiometabolic Risk Factors. | 期刊论文 | Cao Mengying;Wang Hao;Li Wenshu;Jiang Xueli;Wang Xiaolin;Guo Wei;Gao Pan;Zou Yunzeng |
| 7 | PCSK9 participates in oxidized-low density lipoprotein-induced myocardial injury through mitochondrial oxidative stress and Drp1-mediated mitochondrial fission | 期刊论文 | Li Xuan;Dai Fangjie;Wang Hao;Wei Ge;Jiang Qiu;Yin Peipei;Wang Shijun;Ge Junbo;Yang Cheng;Wu Jian;Zou Youzeng |
| 8 | 一种血管缩窄环 | 专利 | 邹云增;胡朝晖;姜红;葛均波;苑洁;龚惠;吴剑;王时俊 |
| 9 | 一种靶向Bach2的小分子激动剂杨梅酮的应用 | 专利 | 邹云增;高攀;蒋雪丽;曹梦颖;王晓琳 |
| 10 | Activation of CXCL16/CXCR6 axis aggravates cardiac ischemia/reperfusion injury by recruiting the IL-17a-producing CD1d+ T cells | 期刊论文 | Wang S;Ma L;Yang J;Dong Z;Wu J;Wang X;Lu J;Dai F;Tu G;Xu L;Zhao G;Zhang F;Zou Y;Ge J |
| 11 | Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload | 期刊论文 | Zou Y;Pan L;Shen Y;Wang X;Huang C;Wang H;Jin X;Yin C;Wang Y;Jia J;Qian J;Zou Y;Gong H;Ge J |
| 12 | Gene expression profiling and functional analysis of ventricular tissues from murine transverse aortic constriction | 期刊论文 | Hao Wang;Yuyao Ji;Zhiwen Ding;Wei Guo;Yunzeng Zou |
| 13 | Variations in energy metabolism precede alterations in cardiac structure and function in hypertrophic preconditioning | 期刊论文 | Wu Jian;Lu Jing;Huang Jiayuan;You Jieyun;Ding Zhiwen;Ma Leilei;Dai Fangjie;Xu Ran;Li Xuan;Yin Peipei;Zhao Gang;Wang Shijun;Yuan Jie;Yang Xiangdong;Ge Junbo;Zou Yunzeng |
| 14 | Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes | 期刊论文 | Ran Xu;Le Kang;Siang Wei;Chunjie Yang;Yuanfeng Fu;Zhiwen Ding;Yunzeng Zou |
| 15 | Involvement of Endoplasmic Reticulum Stress-Mediated Activation of C/EBP Homologous Protein in Aortic Regurgitation-Induced Cardiac Remodeling in Mice | 期刊论文 | Xingxu Wang;Wei Wei;Jian Wu;Le Kang;Shuangquan Wu;Jiming Li;Yunli Shen;Jieyun You;Yong Ye;Qi Zhang;Yunzeng Zou |
| 16 | Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse | 期刊论文 | Jian Wu;Shijun Wang;Le Kang;Chunjie Yang;Jianguo Jia;Xingxu Wang;Ge Wei;Xuan Li;Jieyun You;Yunzeng Zou |
| 17 | Cannabinoid Receptor 2-Centric Molecular Feedback Loop Drives Necroptosis in Diabetic Heart Injuries | 期刊论文 | Pan Gao;Mengying Cao;Xueli Jiang;Xiaolin Wang;Guoping Zhang;Xinru Tang;Chunjie Yang;Issei Komuro;Junbo Ge;Liliang Li;Yunzeng Zou |
| 18 | 一种靶向Bach2的小分子激动剂硫辛酸的应用 | 专利 | 邹云增;高攀;蒋雪丽;曹梦颖;王晓琳 |
| 19 | 核小体蛋白类似蛋白1作为心肌缺血再灌注损伤的治疗靶点 | 专利 | 邹云增;龚惠;王颖;杨春杰 |
| 20 | Oxidized LDL but not angiotensin II induces cardiomyocyte hypertrophic responses through the interaction between LOX-1 and AT1 receptors | 期刊论文 | Lin Li;Zhou Ning;Kang Le;Wang Qi;Wu Jian;Wang Xiaoyan;Yang Chunjie;Zhang Guoping;Chen Yunqin;Jiang Hong;Chen Ruizhen;Yang Xiangdong;Sun Aijun;Gong Hui;Ren Jun;Akazawa Hiroshi;Issel Komuro;Ge Junbo;Yang Cheng;Zou Yunzeng |
| 21 | CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity | 期刊论文 | Li L;Gao P;Tang X;Liu Z;Cao M;Luo R;Li X;Wang J;Lin X;Peng C;Li Z;Zhang J;Zhang X;Cao Z;Zou Y;Jin L |
| 22 | 一种免疫相关转录因子Bach2的应用 | 专利 | 邹云增;高攀;曹梦颖;蒋雪莉;王晓琳 |
| 23 | Protections of transcription factor BACH2 and natural product myricetin against pathological cardiac hypertrophy and dysfunction | 期刊论文 | Xueli Jiang;Mengying Cao;Jian Wu;Xiaolin Wang;Guoping Zhang;Chunjie Yang;Pan Gao;Yunzeng Zou |
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