肠道菌群影响结直肠癌发展和化疗敏感性的研究
81630072
2016
H18.肿瘤学
李孟鸿
重点项目
教授
中山大学
277万元
化疗敏感性;转移;CSN6;结直肠癌;肠道菌群
2017-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF-kappa B Signaling Pathways in Human Gingival Fibroblasts | 期刊论文 | Kang Wenyan;Jia Zhilong;Tang Di;Zhang Zhanwei;Gao Hui;He Kunlun;Feng Qiang |
| 2 | 一种用于清除口臭的口腔喷剂及其制备方法 | 专利 | 冯强;唐迪 |
| 3 | Diabetes mellitus type 2 drives metabolic reprogramming to promote pancreatic cancer growth | 期刊论文 | Velazquez-Torres Guermarie;Fuentes-Mattei Enrique;Choi Hyun Ho;Yeung Sai-Ching J.;Meng Xiangqi;Lee Mong-Hong |
| 4 | 一种用于预防和辅助治疗牙周炎的口腔喷剂及其制备方法 | 专利 | 冯强;唐迪 |
| 5 | Time series analysis of microbiome and metabolome at multiple body sites in steady long-term isolation confinement | 期刊论文 | Feng Qiang;Lan Xiang;Ji Xiaoli;Li Meihui;Liu Shili;Xiong Jianghui;Yu Yanbo;Liu Zhipeng;Xu Zi;He Li;Chen Ying;Dong Haisheng;Chen Pu;Chen Bin;He Kunlun;Li Yinghui |
| 6 | Harness the functions of gut microbiome in tumorigenesis for cancer treatment | 期刊论文 | Lee Mong-hong |
| 7 | CSN6-TRIM21 axis instigates cancer stemness during tumorigenesis. | 期刊论文 | Qin Baifu;Zou Shaomin;Li Kai;Wang Huashe;Wei Wenxia;Zhang Boyu;Xiao Lishi;Choi Hyun Ho;Tang Qin;Huang Dandan;Liu Qingxin;Pan Qihao;Meng Manqi;Fang Lekun;Lee Mong-Hong |
| 8 | Impacts of the Plateau Environment on the Gut Microbiota and Blood Clinical Indexes in Han and Tibetan Individuals | 期刊论文 | Jia Zhilong;Zhao Xiaojing;Liu Xiaoshuang;Zhao Le;Jia Qian;Shi Jinlong;Xu Xiao;Hao Lijun;Xu Zhenguo;Zhong Qin;Yu Kang;Cui Saijia;Chen Huining;Guo Jianying;Li Xiang;Han Yang;Song Xinyu;Zhao Chenghui;Bo Xiaochen;Tian Yaping;Wang Weidong;Xie Guotong;Feng Qiang;He Kunlun |
| 9 | Changes of saliva microbiota in the onset and after the treatment of diabetes in patients with periodontitis | 期刊论文 | Yang Ying;Liu Shili;Wang Yihua;Wang Zhibin;Ding Wenyu;Sun Xiaoyuan;He Kunlun;Feng Qiang;Zhang Xiandang |
| 10 | Time-Course Transcriptome Analysis of Gingiva-Derived Mesenchymal Stem Cells Reveals That Fusobacterium nucleatum Triggers Oncogene Expression in the Process of Cell Differentiation | 期刊论文 | Wenyan Kang;Tianyong Sun;Di Tang;Jiannan Zhou;Qiang Feng |
| 11 | EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis. | 期刊论文 | Choi Hyun Ho;Zou Shaomin;Wu Jian-Lin;Wang Huashe;Phan Liem;Li Kai;Zhang Peng;Chen Daici;Liu Qingxin;Qin Baifu;Nguyen Thu Anh Thai;Yeung Sai-Ching J;Fang Lekun;Lee Mong-Hong |
| 12 | Chitosan attenuates obesity by modifying the intestinal microbiota and increasing serum leptin levels in mice | 期刊论文 | Tang Di;Wang Yihua;Kang Wenyan;Zhou Jiannan;Dong Rui;Feng Qiang |
| 13 | The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts | 期刊论文 | Hui Gao;Tianyong Sun;Fanghong Yang;Jiakan Yuan;Mei Yang;Wenyan Kang;Di Tang;Jun Zhang;Qiang Feng |
| 14 | ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer. | 期刊论文 | Li Kai;Wu Jian-Lin;Qin Baifu;Fan Zongmin;Tang Qin;Lu Weisi;Zhang Haipeng;Xing Fan;Meng Manqi;Zou Shaomin;Wei Wenxia;Chen Honglei;Cai Jian;Wang Huaiming;Zhang Hui;Cai Jiayue;Fang Ling;Bian Xiqing;Chen Chuangqi;Lan Ping;Ghesquière Bart;Fang Lekun;Lee Mong-Hong |
| 15 | Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts | 期刊论文 | Kang Wenyan;Jia Zhilong;Tang Di;Zhao Xiaojing;Shi Jinlong;Jia Qian;He Kunlun;Feng Qiang |
| 16 | Pathogenic and antimicrobial resistance genes in Streptococcus oralis strains revealed by comparative genome analysis | 期刊论文 | Zhou Jiannan;Sun Tianyong;Kang Wenyan;Tang Di;Feng Qiang |
| 17 | Persistent Exposure to Fusobacterium nucleatum Triggers Chemokine/Cytokine Release and Inhibits the Proliferation and Osteogenic Differentiation Capabilities of Human Gingiva-Derived Mesenchymal Stem Cells | 期刊论文 | Kang Wenyan;Ji Xiaoli;Zhang Xiujun;Tang Di;Feng Qiang |
| 18 | ILF3检测试剂在制备结直肠癌诊断试剂中的应用 | 专利 | 方乐堃;李孟鸿;李凯;蒙曼琦 |
| 19 | 一种用于辅助龋齿治疗及预防龋齿的口腔喷剂及其制备方法 | 专利 | 冯强;唐迪 |
| 20 | 一种用于日常口腔健康维护的口腔喷剂及其制备方法 | 专利 | 冯强;唐迪 |
| 21 | Tuning Push-Pull Electronic Effects of AIEgens to Boost the Theranostic Efficacy for Colon Cancer | 期刊论文 | Feng Hai-Tao;Zou Shaomin;Chen Ming;Xiong Feng;Lee Mong-Hong;Fang Lekun;Tang Ben Zhong |
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