程序化释药系统阻断CD47-SIRPα信号通途激活免疫清除人肝癌细胞的递送机制研究

81603040
2016
H3408.药剂学
王翠峰
青年科学基金项目
副教授
中山大学
17万元
RNA干扰;pH敏感性;抑制;程序化释药;CD47;肿瘤免疫治疗
2017-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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1 一种负载5-氨基酮戊酸的纳米药物传递系统及其制备法方法与应用 专利 冯敏;利智;王翠峰;邓慧慧
2 Robust Photodynamic Therapy Using 5-ALA-Incorporated Nanocomplexes Cures Metastatic Melanoma through Priming of CD4( )CD8( ) Double Positive T Cells 期刊论文 Li Zhi;Wang Cuifeng;Deng Huihui;Wu Jiamin;Huang Huan;Sun Ran;Zhang Hongbo;Xiong Xiaoxing;Feng Min
3 "溶液-颗粒"相转变型抗肿瘤药物传递系统及其制备方法 专利 冯敏;张小英;王翠峰;吴佳敏
4 An acid-seeking carrier-free drug achieves high antitumor activity via a "solution-particle" transition 期刊论文 Zhang Xiaoying;Wang Cuifeng;Wu Jiamin;Liu Yajun;Yang Zeping;Zhang Ye;Sui Xiaofeng;Li Min;Feng Min
5 Tunneling Nanotubular Expressways for Ultrafast and Accurate M1 Macrophage Delivery of Anticancer Drugs to Metastatic Ovarian Carcinoma 期刊论文 Guo Ling;Zhang Ye;Yang Zeping;Peng Hui;Wei Runxiu;Wang Cuifeng;Feng Min
6 Lipopolysaccharide-anchored macrophages hijack tumor microtube networks for selective drug transport and augmentation of antitumor effects in orthotopic lung cancer 期刊论文 Guo Ling;Zhang Ye;Wei Runxiu;Wang Cuifeng;Feng Min
7 Pro-inflammatory macrophages-derived extracellular vesicles facilitate anticancer drug delivery to metastatic ovarian cancer 会议论文 Ling Guo;Ye Zhang;Cuifeng Wang;Min Feng
8 Robust Photodynamic Therapy Using 5-ALA-Incorporated Nanocomplexes Cures Metastatic Melanoma through Priming of CD4( )CD8( ) Double Positive T Cells 会议论文 Zhi Li;Huihui Deng;Min Feng;Cuifeng Wang
9 A “Trojan Horse”strategy to target lysosomes in cancer mediated by acidotropic nanomedicine 会议论文 Zeping Yang;Xiaochen Zhang;Min Feng;Cuifeng Wang
10 Closer to Holly Grail: Macromolecular drug-based delivery system for cancer therapy 会议论文 Cuifeng Wang
11 Glutamine addiction activates polyglutamine-based nanocarriers delivering therapeutic siRNAs to orthotopic lung tumor mediated by glutamine transporter SLC1A5 期刊论文 Wang Cuifeng;Wu Jiamin;Wang Zhongjuan;Yang Zeping;Li Zhi;Deng Huihui;Li Long;Peng Xiao;Feng Min
12 Engineering microglia as intraoperative optical imaging agent vehicles potentially for fluorescence-guided surgery in gliomas 期刊论文 Ling Guo;Xiaochen Zhang;Runxiu Wei;Gaojie Li;Bingzhi Sun;Hongbo Zhang;Dan Liu;Cuifeng Wang;Min Feng
13 Ultrafast and Accurate M1 Macrophage Delivery of Anticancer Drugs. 会议论文 Ling Guo;Ye Zhang;Cuifeng Wang;Min Feng
14 A Glutamine-Rich Carrier Efficiently Delivers Anti-CD47 siRNA Driven by a "Glutamine Trap" To Inhibit Lung Cancer Cell Growth 期刊论文 Wu Jiamin;Li Zhi;Yang Zeping;Guo Ling;Zhang Ye;Deng Huihui;Wang Cuifeng;Feng Min
15 "溶液-颗粒"相转变型抗肿瘤药物传递系统及其制备方法 专利 冯敏;张小英;王翠峰;吴佳敏
16 An acid-seeking carrier-free drug achieves high antitumor activity via a "solution-particle" transition 期刊论文 Zhang Xiaoying;Wang Cuifeng;Wu Jiamin;Liu Yajun;Yang Zeping;Zhang Ye;Sui Xiaofeng;Li Min;Feng Min
17 A Glutamine-Rich Carrier Efficiently Delivers Anti-CD47 siRNA Driven by a "Glutamine Trap" To Inhibit Lung Cancer Cell Growth 期刊论文 Wu Jiamin;Li Zhi;Yang Zeping;Guo Ling;Zhang Ye;Deng Huihui;Wang Cuifeng;Feng Min
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