NLRP3炎症小体-IDO1-犬尿氨酸信号调控海马小胶质细胞活化参与抑郁症形成的机制研究及其治疗价值
31871029
2018
C0901.分子与细胞神经生物学
刘琼
面上项目
教授
复旦大学
59万元
NLRP3炎症小体;抑郁症;吲哚胺2;小胶质细胞;3-二氧化酶1;活化
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress | 期刊论文 | Zhangshanshan;Hujuntao;Liuguixue;Wuhaoran;Limeihui;Shichenye;LiuQiong;Liwensheng |
| 2 | Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors. | 期刊论文 | Zhang Shanshan;Zong Ying;Ren Zhonggan;Hu Juntao;Wu Xinyuan;Xiao Honglei;Qin Song;Zhou Guomin;Ma Yuanyuan;Zhang Yaodong;Yu Jin;Wang Kaidi;Lu Guocai;Liu Qiong |
| 3 | Catalpol ameliorates depressive-like behaviors in CUMS mice via oxidative stress-mediated NLRP3 inflammasome and neuroinflammation | 期刊论文 | Wang Ya-lin;Wu Hao-ran;Zhang Shan-shan;Xiao Hong-lei;Yu Jin;Ma Yuan-yuan;Zhang Yao-dong;Liu Qiong |
| 4 | Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine | 期刊论文 | Gong Wenqing;Zhang Shanshan;Zong Ying;Halim Michael;Ren Zhonggan;Wang Yalin;Ma Yuanyuan;Li Bing;Ma Lixiang;Zhou Guomin;Yu Jin;Zhang Junhai;Liu Qiong |
| 5 | Microglia activation in the hippocampus mediates retinal degeneration-induced depressive-like behaviors via the NLRP3/IL-1β pathway | 期刊论文 | TianYi;Limeihui;Zhangshanshan;Hujuntao;Wuhaoran;Mitchell Wan;Xuejingxin;Wangleilei;Xiaohonglei;Zhouguoming;Wangkaidi;LiuQiong |
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