核糖体蛋白的O-GlcNAc糖基化修饰在肝细胞癌发生发展中的功能和机制研究
31630088
2016
C0506.糖、脂生物化学
顾建新
重点项目
教授
复旦大学
272万元
O-连接的β-N-乙酰葡萄糖胺转移酶;肝细胞癌;核糖体;O-连接的β-N-乙酰葡萄糖胺;蛋白质翻译
2017-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Decreased expression of STING predicts poor prognosis in patients with gastric cancer | 期刊论文 | Song Shushu;Peng Peike;Tang Zhaoqing;Zhao Junjie;Wu Weicheng;Li Haojie;Shao Miaomiao;Li Lili;Yang Caiting;Duan Fangfang;Zhang Mingming;Zhang Jie;Wu Hao;Li Can;Wang Xuefei;Wang Hongshan;Ruan Yuanyuan;Gu Jianxin |
| 2 | Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity | 期刊论文 | Yang Tianxiao;Wang Yilin;Dai Wenjuan;Zheng Xixi;Wang Jing;Song Shushu;Fang Lan;Zhou Jiangfan;Wu Weicheng;Gu Jianxin |
| 3 | Diagnostic Significance of Serum IgG Galactosylation in CA19-9-Negative Pancreatic Carcinoma Patients | 期刊论文 | Zhong Ailing;Qin Ruihuan;Qin Wenjun;Han Jing;Gu Yong;Zhou Lei;Zhang Hongqin;Ren Shifang;Lu Renquan;Guo Lin;Gu Jianxin |
| 4 | The IgG galactosylation ratio is higher in spondyloarthritis patients and associated with the MRI score | 期刊论文 | Liu Jing;Zhu Qi;Han Jing;Zhang Hui;Li Yuan;Ma Yanyun;Ji Hengdong;He Dongyi;Gu Jianxin;Zhou Xiaodong;Reveille John D;Jin Li;Zou Hejian;Ren Shifang;Wang Jiucun |
| 5 | pVHL promotes lysosomal degradation of YAP in lung adenocarcinoma | 期刊论文 | Hu Lan;Wu Hao;Jiang Tian;Kuang Mengzhen;Liu Bo;Guo Xinying;He Daochuan;Chen Mengqian;Gu Jie;Gu Jianxin;Chang Lei;Feng Mingxiang;Ruan Yuanyuan |
| 6 | Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals | 期刊论文 | Dai Wenjuan;Wang Yilin;Yang Tianxiao;Wang Jing;Wu Weicheng;Gu Jianxin |
| 7 | Up-regulation of FUT8 inhibits TGF-β1-induced activation of hepatic stellate cells during liver fibrogenesis | 期刊论文 | Kuang Mengzhen;Wu Hao;Hu Lan;Guo Xinying;He Daochuan;Liu Bo;Chen Mengqian;Gu Jie;Gu Jianxin;Zeng Xiaoqing;Ruan Yuanyuan |
| 8 | A nomogram based on glycomic biomarkers in serum and clinicopathological characteristics for evaluating the risk of peritoneal metastasis in gastric cancer | 期刊论文 | Zhao Junjie;Qin Ruihuan;Chen Hao;Yang Yupeng;Qin Wenjun;Han Jing;Wang Xuefei;Ren Shifang;Sun Yihong;Gu Jianxin |
| 9 | Alteration of Serum IgG Galactosylation as a Potential Biomarker for Diagnosis of Neuroblastoma | 期刊论文 | Qin Wenjun;Pei Hao;Qin Ruihuan;Zhao Ran;Han Jing;Zhang Zejian;Dong Kuiran;Ren Shifang;Gu Jianxin |
| 10 | Prediction of neoadjuvant chemotherapeutic efficacy in patients with locally advanced gastric cancer by serum IgG glycomics profiling | 期刊论文 | Qin Ruihuan;Yang Yupeng;Chen Hao;Qin Wenjun;Han Jing;Gu Yong;Pan Yiqing;Cheng Xi;Zhao Junjie;Wang Xuefei;Ren Shifang;Sun Yihong;Gu Jianxin |
| 11 | The Value of Serum Immunoglobulin G Glycome in the Preoperative Discrimination of Peritoneal Metastasis from Advanced Gastric Cancer | 期刊论文 | Qin Ruihuan;Yang Yupeng;Qin Wenjun;Han Jing;Chen Hao;Zhao Junjie;Zhao Ran;Li Can;Gu Yong;Pan Yiqing;Wang Xuefei;Ren Shifang;Sun Yihong;Gu Jianxin |
| 12 | 岩藻聚糖在制备抑制LOX-1信号途径药物中的应用 | 专利 | 顾建新;汪澜;李灿;许玲;李姝璇 |
| 13 | High expression of GFAT1 predicts unfavorable prognosis in patients with hepatocellular carcinoma | 期刊论文 | Li Lili;Shao Miaomiao;Peng Peike;Yang Caiting;Song Shushu;Duan Fangfang;Jia Dongwei;Zhang Mingming;Zhao Junjie;Zhao Ran;Wu Weicheng;Wang Lan;Li Can;Wu Hao;Zhang Jie;Wu Xin;Ruan Yuanyuan;Gu Jianxin |
| 14 | Providing Bionic Glycome as internal standards by glycan reducing and isotope labeling for reliable and simple quantitation of N-glycome based on MALDI- MS | 期刊论文 | Qin Wenjun;Zhang Zejian;Qin Ruihuan;Han Jing;Zhao Ran;Gu Yong;Pan Yiqing;Gu Jianxin;Ren Shifang |
| 15 | O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis | 期刊论文 | Duan Fangfang;Wu Hao;Jia Dongwei;Wu Weicheng;Ren Shifang;Wang Lan;Song Shushu;Guo Xinying;Liu Fenglin;Ruan Yuanyuan;Gu Jianxin |
| 16 | Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus | 期刊论文 | Song Shushu;Shi Yinghong;Wu Weicheng;Wu Hao;Chang Lei;Peng Peike;Zhang Lei;Fan Jia;Gu Jianxin;Ruan Yuanyuan |
| 17 | IgG Galactosylation status combined with MYOM2-rs2294066 precisely predicts anti-TNF response in ankylosing spondylitis | 期刊论文 | Liu Jing;Zhu Qi;Han Jing;Zhang Hui;Li Yuan;Ma Yanyun;He Dongyi;Gu Jianxin;Zhou Xiaodong;Reveille John D.;Jin Li;Zou Hejian;Ren Shifang;Wang Jiucun |
| 18 | Relative Quantitation of Subclass-Specific Murine IgG Fc N-Glycoforms by Multiple Reaction Monitoring | 期刊论文 | Han Jing;Liu Qingmei;Xu Xiaoyan;Qin Wenjun;Pan Yiqing;Qin Ruihuan;Zhao Ran;Gu Yong;Gu Jianxin;Ren Shifang |
| 19 | O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma | 期刊论文 | Wu Weicheng;Zheng Xixi;Wang Jing;Yang Tianxiao;Dai Wenjuan;Song Shushu;Fang Lan;Wang Yilin;Gu Jianxin |
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