蜕膜CXCR4+与CXCR4-NK细胞在CD4+T细胞亚群平衡与母-胎免疫耐受中的调节作用

31570920
2015
C0807.生殖免疫与移植免疫
杜美蓉
面上项目
研究员
复旦大学
60万元
反复自然流产;滋养细胞;母-胎界面;蜕膜NK细胞;母-胎免疫
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Galectin-9 promotes human trophoblast cell invasion via MMP-2 and p38 signaling. 期刊论文 Sun FR;Chen CQ;Yu M;Wang SC;Li DJ;Du MR
2 Bidirectional regulation between 1st trimester HTR8/SVneo trophoblast cells and in vitro differentiated Th17/Treg cells suggest a fetal-maternal regulatory loop in human pregnancy 期刊论文 Wang Songcun;Qian Jinfeng;Sun Fengrun;Li Mengdie;Ye Jiangfeng;Li Mingqing;Du Meirong;Li Dajin
3 Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4(+) T cells to induce Type 2 helper T cell (Th2) bias at the maternal-fetal interface 期刊论文 Wang Songcun;Zhu Xiaoyong;Xu Yuanyuan;Zhang Di;Li Yanhong;Tao Yu;Piao Hailan;Li Dajin;Du Meirong
4 The appropriate frequency and function of decidual Tim-3( )CTLA-4( )CD8( ) T cells are important in maintaining normal pregnancy 期刊论文 Wang Songcun;Sun Fengrun;Li Mengdie;Qian Jinfeng;Chen Chunqin;Wang Mingyan;Zang Xingxing;Li Dajin;Yu Min;Du Meirong
5 Activation of Rev-erba attenuates lipopolysaccharide-induced inflammatory reactions in human endometrial stroma cells via suppressing TLR4-regulated NF-kappa B activation 期刊论文 Zhao Weijie;Cui Liyuan;Huang Xixi;Wang Songcun;Li Dajin;Li Liping;Sun Yan;Du Meirong
6 Inhibition of AKT sensitizes chemoresistant ovarian cancer cells to cisplatin by abrogating S and G2/M arrest 期刊论文 Zhang Di;Piao Hai-Lan;Li Yan-Hong;Li Da-Jin;Du Mei-Rong;Tsang Benjamin K.
7 Co-Signaling Molecules in Maternal-Fetal lmmunity 期刊论文 Xu Yuan-Yuan;Wang Song-Cun;Li Da-Jin;Du Mei-Rong
8 Cell-cell contact with proinflammatory macrophages enhances the immunotherapeutic effect by mesenchymal stem cells in two abortion models 期刊论文 Li Yanhong;Zhang Di;Xu Ling;Dong Lin;Zheng Ji;Lin Yikong;Huang Jiefang;Zhang Yanyun;Tao Yu;Zang Xingxing;Li Dajin;Du Meirong
9 Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss 期刊论文 Li Yanhong;Zhang Jiayuan;Zhang Di;Hong Xiaowu;Tao Yu;Wang Songcun;Xu Yuanyuan;Piao Hailan;Yin Weijie;Yu Min;Zhang Yin;Fu Qiang;Li Dajin;Chang Xing;Du Meirong
10 SCM-198 protects endometrial stromal cells from oxidative damage through Bax/Bcl-2 and ERK signaling pathways 期刊论文 Li Yunyun;Lin Yikong;Huang Xixi;Xu Chunfang;Liu Xinhua;Wang Li;Yu Min;Li Dajin;Zhu Yizhun;Du Meirong
11 Iron Metabolism Regulation and Diseases. 期刊论文 Sun FR;Wang SC;Li DJ;Du MR
12 Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4( )T cells 期刊论文 Wang Songcun;Chen Chunqin;Li Mengdie;Qian Jinfeng;Sun Fengyun;Li Yunyun;Yu Min;Wang Mingyan;Zang Xingxing;Zhu Rui;Li Dajin;Du Meirong
13 Trophoblast-derived hyaluronan promotes the regulatory phenotype of decidual macrophages 期刊论文 Wang Songcun;Sun Fengrun;Han Mutian;Liu Yinghua;Zou Qinyan;Wang Fuxin;Tao Yu;Li Dajin;Du Meirong;Li Hong;Zhu Rui
14 Tim-3 and PD-1 regulate CD8(+) T cell function to maintain early pregnancy in mice 期刊论文 Xu Yuan-Yuan;Wang Song-Cun;Lin Yi-Kong;Li Da-Jin;Du Mei-Rong
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