肝细胞癌中核糖体蛋白RACK1的O-GlcNAc糖基化修饰的调控机制和功能意义研究
31370808
2013
C0506.糖、脂生物化学
阮元元
面上项目
教授
复旦大学
80万元
肝细胞癌;核糖体;活化蛋白激酶C受体1;O-连接的β-N-乙酰葡萄糖胺;蛋白质翻译
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma | 期刊论文 | Wang Jiajun;Shao Miaomiao;Liu Min;Peng Peike;Li Lili;Wu Weicheng;Wang Lan;Duan Fangfang;Zhang Mingming;Song Shushu;Jia Dongwei;Ruan Yuanyuan;Gu Jianxin |
| 2 | Decreased expression of STING predicts poor prognosis in patients with gastric cancer. | 期刊论文 | Song Shushu;Peng Peike;Tang Zhaoqing;Zhao Junjie;Wu Weicheng;Li Haojie;Shao Miaomiao;Li Lili;Yang Caiting;Duan Fangfang;Zhang Mingming;Zhang Jie;Wu Hao;Li Can;Wang Xuefei;Wang Hongshan;Ruan Yuanyuan;Gu Jianxin |
| 3 | High Intratumoral Expression of Tetranectin Associates with Poor Prognosis of Patients with Gastric Cancer after Gastrectomy. | 期刊论文 | Chen Hao;Li Haojie;Zhao Junjie;Peng Peike;Shao Miaomiao;Wu Hao;Wang Xuefei;Chen Ling;Zhang Qi;Ruan Yuanyuan;Liu Fenglin;Sun Yihong |
| 4 | High expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer. | 期刊论文 | Yang Caiting;Peng Peike;Li Lili;Shao Miaomiao;Zhao Junjie;Wang Lan;Duan Fangfang;Song Shushu;Wu Hao;Zhang Jie;Zhao Ran;Jia Dongwei;Zhang Mingming;Wu Weicheng;Li Can;Rong Yefei;Zhang Lei;Ruan Yuanyuan;Gu Jianxin |
| 5 | Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop. | 期刊论文 | Chen Ling;Min Lingqiang;Wang Xuefei;Zhao Junjie;Chen Hua;Qin Jing;Chen Weidong;Shen Zhenbin;Tang Zhaoqing;Gan Qiangjun;Ruan Yuanyuan;Sun Yihong;Qin Xinyu;Gu Jianxin |
| 6 | RACK1-mediated translation control promotes liver fibrogenesis | 期刊论文 | Liu Min;Peng Peike;Wang Jiajun;Wang Lan;Duan Fangfang;Jia Dongwei;Ruan Yuanyuan;Gu Jianxin |
| 7 | High expression of GFAT1 predicts unfavorable prognosis in patients with hepatocellular carcinoma | 期刊论文 | Li Lili;Shao Miaomiao;Peng Peike;Yang Caiting;Song Shushu;Duan Fangfang;Jia Dongwei;Zhang Mingming;Zhao Junjie;Zhao Ran;Wu Weicheng;Wang Lan;Li Can;Wu Hao;Zhang Jie;Wu Xin;Ruan Yuanyuan;Gu Jianxin |
| 8 | E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation. | 期刊论文 | Shao Miaomiao;Li Lili;Song Shushu;Wu Weicheng;Peng Peike;Yang Caiting;Zhang Mingming;Duan Fangfang;Jia Dongwei;Zhang Jie;Wu Hao;Zhao Ran;Wang Lan;Ruan Yuanyuan;Gu Jianxin |
| 9 | Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients. | 期刊论文 | Min Lingqiang;Ruan Yuanyuan;Shen Zhenbin;Jia Dongwei;Wang Xuefei;Zhao Junjie;Sun Yihong;Gu Jianxin |
| 10 | Decreased expression of Calpain-9 predicts unfavorable prognosis in patients with gastric cancer. | 期刊论文 | Peng Peike;Wu Weicheng;Zhao Junjie;Song Shushu;Wang Xuefei;Jia Dongwei;Shao Miaomiao;Zhang Mingming;Li Lili;Wang Lan;Duan Fangfang;Zhao Ran;Yang Caiting;Wu Hao;Zhang Jie;Shen Zhenbin;Ruan Yuanyuan;Gu Jianxin |
| 11 | Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer. | 期刊论文 | Duan Fangfang;Jia Dongwei;Zhao Junjie;Wu Weicheng;Min Lingqiang;Song Shushu;Wu Hao;Wang Lan;Wang Hongshan;Ruan Yuanyuan;Gu Jianxin |
| 12 | Hepsin inhibits CDK11p58 IRES activity by suppressing unr expression and eIF-2alpha phosphorylation in prostate cancer | 期刊论文 | Zhang Chunyi;Zhang Mingming;Wu Qingyu;Peng Jianhao;Ruan Yuanyuan;Gu Jianxin |
| 13 | C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits. | 期刊论文 | Wang Lan;Yin Jie;Wang Xuefei;Shao Miaomiao;Duan Fangfang;Wu Weicheng;Peng Peike;Jin Jing;Tang Yue;Ruan Yuanyuan;Sun Yihong;Gu Jianxin |
| 14 | Elevated Expression of Calpain-4 Predicts Poor Prognosis in Patients with Gastric Cancer after Gastrectomy. | 期刊论文 | Peng Peike;Min Lingqiang;Song Shushu;Zhao Junjie;Li Lili;Yang Caiting;Shao Miaomiao;Zhang Mingming;Wu Hao;Zhang Jie;Li Can;Wang Xuefei;Wang Hongshan;Qin Jing;Ruan Yuanyuan;Gu Jianxin |
| 15 | Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice | 期刊论文 | Jia Dongwei;Duan Fangfang;Peng Peike;Sun Linlin;Ruan Yuanyuan;Gu Jianxin |
| 16 | Loss of OLFM4 promotes tumor migration through inducing interleukin-8 expression and predicts lymph node metastasis in early gastric cancer. | 期刊论文 | Zhao Junjie;Shu Ping;Duan Fangfang;Wang Xuefei;Min Linqiang;Shen Zhenbing;Ruan Yuanyuan;Qin Jing;Sun Yihong;Qin Xinyu |
| 17 | O-GlcNAc糖基化修饰在防治肝纤维化中的应用 | 专利 | 顾建新;阮元元;贾冬威;宋淑淑;邵苗苗;李莉莉 |
| 18 | Decreased expression of STING predicts poor prognosis in patients with gastric cancer. | 期刊论文 | Song Shushu;Peng Peike;Tang Zhaoqing;Zhao Junjie;Wu Weicheng;Li Haojie;Shao Miaomiao;Li Lili;Yang Caiting;Duan Fangfang;Zhang Mingming;Zhang Jie;Wu Hao;Li Can;Wang Xuefei;Wang Hongshan;Ruan Yuanyuan;Gu Jianxin |
| 19 | Loss of OLFM4 promotes tumor migration through inducing interleukin-8 expression and predicts lymph node metastasis in early gastric cancer. | 期刊论文 | Zhao Junjie;Shu Ping;Duan Fangfang;Wang Xuefei;Min Linqiang;Shen Zhenbing;Ruan Yuanyuan;Qin Jing;Sun Yihong;Qin Xinyu |
| 20 | C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits. | 期刊论文 | Wang Lan;Yin Jie;Wang Xuefei;Shao Miaomiao;Duan Fangfang;Wu Weicheng;Peng Peike;Jin Jing;Tang Yue;Ruan Yuanyuan;Sun Yihong;Gu Jianxin |
| 21 | Elevated Expression of Calpain-4 Predicts Poor Prognosis in Patients with Gastric Cancer after Gastrectomy. | 期刊论文 | Peng Peike;Min Lingqiang;Song Shushu;Zhao Junjie;Li Lili;Yang Caiting;Shao Miaomiao;Zhang Mingming;Wu Hao;Zhang Jie;Li Can;Wang Xuefei;Wang Hongshan;Qin Jing;Ruan Yuanyuan;Gu Jianxin |
| 22 | Decreased expression of Calpain-9 predicts unfavorable prognosis in patients with gastric cancer. | 期刊论文 | Peng Peike;Wu Weicheng;Zhao Junjie;Song Shushu;Wang Xuefei;Jia Dongwei;Shao Miaomiao;Zhang Mingming;Li Lili;Wang Lan;Duan Fangfang;Zhao Ran;Yang Caiting;Wu Hao;Zhang Jie;Shen Zhenbin;Ruan Yuanyuan;Gu Jianxin |
| 23 | High expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer. | 期刊论文 | Yang Caiting;Peng Peike;Li Lili;Shao Miaomiao;Zhao Junjie;Wang Lan;Duan Fangfang;Song Shushu;Wu Hao;Zhang Jie;Zhao Ran;Jia Dongwei;Zhang Mingming;Wu Weicheng;Li Can;Rong Yefei;Zhang Lei;Ruan Yuanyuan;Gu Jianxin |
| 24 | High Intratumoral Expression of Tetranectin Associates with Poor Prognosis of Patients with Gastric Cancer after Gastrectomy. | 期刊论文 | Chen Hao;Li Haojie;Zhao Junjie;Peng Peike;Shao Miaomiao;Wu Hao;Wang Xuefei;Chen Ling;Zhang Qi;Ruan Yuanyuan;Liu Fenglin;Sun Yihong |
| 25 | E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation. | 期刊论文 | Shao Miaomiao;Li Lili;Song Shushu;Wu Weicheng;Peng Peike;Yang Caiting;Zhang Mingming;Duan Fangfang;Jia Dongwei;Zhang Jie;Wu Hao;Zhao Ran;Wang Lan;Ruan Yuanyuan;Gu Jianxin |
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