TBC1d23调节细胞器互作及突变引起脑桥小脑发育不全的机制研究
91854121
2018
C0701.细胞器及亚细胞结构、互作与功能
贾大
重大研究计划
教授
四川大学
89万元
内吞体（endosome）;fission）囊泡运输（vesicular;蛋白质分选（protein;神经疾病;sorting）;囊泡融合（vesicle;突触囊泡（synaptic;vesicle）;fusion）囊泡分裂（vesicle;transport）
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis | 期刊论文 | Zheng Lvqin;Liu Zhe;Wang Yan;Yang Fan;Wang Jinrui;Huang Wenjie;Qin Jiao;Tian Min;Cai Xiaotang;Liu Xiaohui;Mo Xianming;Gao Ning;Jia Da |
| 2 | All ways lead to Rome: assembly of retromer on membranes with different sorting nexins | 期刊论文 | Key Laboratory of Birth Defects;Related Diseases of Women;Children Department of Paediatrics West China Second University Hospital State Key Laboratory of Biotherapy;Collaborative Innovation Center of Biotherapy Sichuan University Chengdu China. |
| 3 | Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH | 期刊论文 | Huang Wenjie;Liu Zhe;Yang Fan;Zhou Huan;Yong Xin;Yang Xiaoyu;Zhou Yifei;Xue Lijia;Zhang Yihong;Liu Dingdong;Meng Wentong;Zhang Wenming;Zhang Xiaohu;Shen Xiaofei;Sun Qingxiang;Li Li;Ma Cong;Wei Yuquan;Billadeau Daniel D;Mo Xianming;Jia Da |
| 4 | Structural and mechanistic insights into secretagogin-mediated exocytosis | 期刊论文 | Jiao Qin;Qi Liu;zhe Liu;Yun-Zu Pan;Luis Sifuentes-Dominguez;Karolina P Stepien;Yan Wang;Yingfeng Tu;Shuai Tan;Yuan Wang;Qingxiang Sun;Xianming Mo;Josep Rizo;Ezra Burstein;Da Jia |
| 5 | Mechanism of cargo recognition by retromer-linked SNX-BAR proteins | 期刊论文 | Xin Yong;Lin Zhao;Wankun Deng;Hongbin Sun;Xue Zhou;Lejiao Mao;Wenfeng Hu;Xiaofei Shen;Qingxiang Sun;Daniel D Billadeau;Yu Xue;Da Jia |
| 6 | Model-based analysis uncovers mutations altering autophagy selectivity in human cancer | 期刊论文 | Han Zhu;Zhang Weizhi;Ning Wanshan;Wang Chenwei;Deng Wankun;Li Zhidan;Shang Zehua;Shen Xiaofei;Liu Xiaohui;Baba Otto;Morita Tsuyoshi;Chen Lu;Xue Yu;Jia Da |
| 7 | SNX27-FERM-SNX1 complex structure rationalizes divergent trafficking pathways by SNX17 and SNX27 | 期刊论文 | Yong X;Zhao L;Hu W;Sun Q;Ham H;Liu Z;Ren J;Zhang Z;Zhou Y;Yang Q;Mo X;Hu J;Billadeau DD;Jia D |
| 8 | Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain | 期刊论文 | Liu Dingdong;Yang Fan;Liu Zhe;Wang Jinrui;Huang Wenjie;Meng Wentong;Billadeau Daniel D.;Sun Qingxiang;Mo Xianming;Jia Da |
| 9 | Phosphorylation of SNX27 by MAPK11/14 links cellular stress-signaling pathways with endocytic recycling | 期刊论文 | Lejiao Mao;Chenyi Liao;Jiao Qin;Yanqiu Gong;Yifei Zhou;Shasha Li;Zhe Liu;Huaqing Deng;Wankun Deng;Qingxiang Sun;Xianming Mo;Yu Xue;Daniel D Billadeau;Lunzhi Dai;Guohui Li;Da Jia |
| 10 | iCAL: a new pipeline to investigate autophagy selectivity and cancer | 期刊论文 | Zhang Weizhi;Han Zhu;Xue Yu;Jia Da |
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