人原始生殖细胞中的关键组蛋白修饰动态调控机制研究
31871446
2018
C1206.生殖细胞及性别决定
陈嘉瑜
面上项目
教授
同济大学
59万元
表观遗传重编程;原始生殖细胞;组蛋白修饰;人
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer. | 期刊论文 | Yang Guang;Zhang Linfeng;Liu Wenqiang;Qiao Zhibin;Shen Shijun;Zhu Qianshu;Gao Rui;Wang Mengting;Wang Mingzhu;Li Chong;Liu Meng;Sun Jin;Wang Liping;Liu Wenju;Cui Xinyu;Zhao Kun;Zang Ruge;Chen Mo;Liang Zehang;Wang Lu;Kou Xiaochen;Zhao Yanhong;Wang Hong;Wang Yixuan;Gao Shaorong;Chen Jiayu;Jiang Cizhong |
| 2 | 中国细胞生物学学会2020年全国学术大会苏州-优秀墙报奖 | 奖励 | 陈嘉瑜 |
| 3 | 中国干细胞第十届年会青年杰出学术报告一等奖 | 奖励 | 陈嘉瑜 |
| 4 | Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs | 期刊论文 | Gao Haibo;Gao Rui;Zhang Linfeng;Xiu Wenchao;Zang Ruge;Wang Hong;Zhang Yong;Chen Jiayu;Gao Yawei;Gao Shaorong |
| 5 | 生长因子诱导生成神经前体细胞的方法 | 专利 | 高绍荣;高睿;陈嘉瑜;张林凤;臧茹歌;刘文强;陈珺 |
| 6 | 有助于诱导生成神经前体细胞的诱导培养基 | 专利 | 高绍荣;陈嘉瑜;高睿;张林凤;臧茹歌;王明珠;高亚威;陈珺 |
| 7 | 一种杜鹃素在基因编辑中的应用 | 专利 | 蒋颖;张伟娜;陈御;陈嘉瑜;高绍荣;毛志勇 |
| 8 | Resetting Histone Modifications During Human Prenatal Germline Development | 期刊论文 | Rui Gao;Shiyang Zeng;Dongxu Yang;Xiaocui Li;Wenqiang Liu;Yawei Gao;Dandan Bai;Linfeng Zhang;Chuan Chen;Yunzhe Kang;Beiying Wang;Wei Hong;Mingzhu Wang;Jiqing Yin;Hong Wang;Qiaolin Deng;Shaorong Gao;Yong Zhang;Jiayu Chen |
| 9 | 早期胚胎发育与体细胞重编程的表观调控机制研究 | 奖励 | 高绍荣;高亚威;张勇;陈嘉瑜;鞠振宇 |
| 10 | 早期胚胎发育与体细胞重编程的表观调控机制研究 | 奖励 | 高绍荣;颉伟;高亚威;张勇;陈嘉瑜;那洁;刘晓雨;刘文强;江赐忠 |
| 11 | The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells | 期刊论文 | Chen Yu;Chen Jiayu;Sun Xiaoxiang;Yu Jiayu;Qian Zhen;Wu Li;Xu Xiaojun;Wan Xiaoping;Jiang Ying;Zhang Jian;Gao Shaorong;Mao Zhiyong |
| 12 | A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing. | 期刊论文 | Zhang Weina;Chen Yu;Yang Jiaqing;Zhang Jing;Yu Jiayu;Wang Mengting;Zhao Xiaodong;Wei Ke;Wan Xiaoping;Xu Xiaojun;Jiang Ying;Chen Jiayu;Gao Shaorong;Mao Zhiyong |
| 13 | Mammalian haploid stem cells: establishment, engineering and applications | 期刊论文 | He Wenteng;Chen Jiayu;Gao Shaorong |
| 14 | BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding. | 期刊论文 | Wang Mingzhu;Zhao Kun;Liu Meng;Wang Mengting;Qiao Zhibin;Yi Shanru;Jiang Yonghua;Kou Xiaochen;Zhao Yanhong;Yin Jiqing;Li Tianming;Wang Hong;Jiang Cizhong;Gao Shaorong;Chen Jiayu |
| 15 | 一种等位特异性位点编辑方法 | 专利 | 高绍荣;刘文强;李延鹤;翁雨藤;柏丹丹;陈嘉瑜;殷吉庆 |
| 16 | Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1. | 期刊论文 | Li Yingfeng;Zhang Zhuqiang;Chen Jiayu;Liu Wenqiang;Lai Weiyi;Liu Baodong;Li Xiang;Liu Liping;Xu Shaohua;Dong Qiang;Wang Mingzhu;Duan Xiaoya;Tan Jiajun;Zheng Yong;Zhang Pumin;Fan Guoping;Wong Jiemin;Xu Guo-Liang;Wang Zhigao;Wang Hailin;Gao Shaorong;Zhu Bing |
| 17 | Chromatin architecture reorganization during somatic cell reprogramming. | 期刊论文 | Zhao Kun;Wang Mingzhu;Gao Shaorong;Chen Jiayu |
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