磷酸化修饰调控SET1A活性及其在肿瘤中的机制及功能研究
31871398
2018
C0702.细胞信号转导
方兰
面上项目
教授
同济大学
60万元
肿瘤微环境因子;肿瘤发生发展;磷酸化;SET1A;信号转导
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness | 期刊论文 | Wang Xinbo;Jin Jiali;Wan Fangning;Zhao Linlin;Chu Hongshang;Chen Cong;Liao Guanghong;Liu Jian;Yu Yue;Teng Hongqi;Fang Lan;Jiang Cong;Pan Weijuan;Xie Xin;Li Jia;Lu Xiaolin;Jiang Xuejun;Ge Xin;Ye Dingwei;Wang Ping |
| 2 | Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer | 期刊论文 | Jiawen Zhang;Yunfei Chen;Xianfei Chen;Wen Zhang;Linlin Zhao;Linjun Weng;Hongling Tian;Zhiqiang Wu;Xiao Tan;Xin Ge;Ping Wang;Lan Fang |
| 3 | AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation | 期刊论文 | Wang Zhen;Kang Li;Zhang Huifang;Huang Yuanyong;Fang Lan;Li Menghan;Brown Peter J.;Arrowsmith Cheryl H.;Li Jiwen;Wong Jiemin |
| 4 | 可作为肿瘤诊断和预后分析标志物的cGAS甲基化修饰及其检测试剂和应用 | 专利 | 王平;方兰 |
| 5 | NNMT-DNMT1 Axis is Essential for Maintaining Cancer Cell Sensitivity to Oxidative Phosphorylation Inhibition | 期刊论文 | Changqing Wu;Yu’e Liu;Wenju Liu;Tianhui Zou;Shaojuan Lu;Chengjie Zhu;Le He;Jie Chen;Lan Fang;Lin Zou;Ping Wang;Lihong Fan;Hongxiang Wang;Han You;Juxiang Chen;Jing-Yuan Fang;Cizhong Jiang;Yufeng Shi |
| 6 | Identification of Glutaminyl Cyclase isoenzyme isoQC as a regulator of SIRP alpha-CD47 axis | 期刊论文 | Wu Zhiqiang;Weng Linjun;Zhang Tengbo;Tian Hongling;Fang Lan;Teng Hongqi;Zhang Wen;Gao Jing;Hao Yun;Li Yaxu;Zhou Hu;Wang Ping |
| 7 | PD-L1 regulates genomic stability via interaction with cohesin-SA1 in the nucleus | 期刊论文 | Wen Zhang;Yanjin Wang;Yanjin Wang;Lan Fang;Liu Min;Xinbo Wang;Lin Ding;Linjun Weng;Xiao Tan;Tianhua Zhou;Ping Wang |
| 8 | 一种TREX1基因变异引起的疾病的治疗靶点及其应用 | 专利 | 王平;方兰 |
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