铜绿假单胞菌ExoY调控选择性自噬降解TAB1从而抑制宿主免疫反应的机制研究
31730025
2017
C0806.感染与非感染性炎症
戈宝学
重点项目
教授
同济大学
286万元
固有免疫;炎症反应;免疫调节;信号转导;细菌
2018-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Interception of host fatty acid metabolism by mycobacteria under hypoxia to suppress anti-TB immunity | 期刊论文 | Hua Yang;Fei Wang;Xinya Guo;Feng Liu;Zhonghua Liu;Xiangyang Wu;Mengmeng Zhao;Mingtong Ma;Haipeng Liu;Lianhua Qin;Lin Wang;Tianqi Tang;Wei Sha;Yang Wang;Jianxia Chen;Xiaochen Huang;Jie Wang;Cheng Peng;Ruijuan Zheng;Fen Tang;Lu Zhang;Chunyan Wu;Stefan H. Oehlers;Zhigang Song;Jialei She;Hua Feng;Xunwei Xie;Baoxue Ge |
| 2 | Genome-wide association study identifies two new risk loci for TB in Han Chinese | 期刊论文 | Ruijuan Zheng;Zhiqiang Li;Fusheng He;Haipeng Liu;Jianhua Chen;Jiayu Chen;Xuefeng Xie;Juan Zhou;Hao Chen;Xiangyang Wu;Juehui Wu;Boyu Chen;Yahui Liu;Haiyan Cui;Lin Fan;Wei Sha;Yin Liu;Jiqiang Wang;Xiaochen Huang;Linfeng Zhang;Feifan Xu;Jie Wang;Yonghong Feng;Lianhua Qin;Hua Yang;Zhonghua Liu;Zhenglin Cui;Feng Liu;Xinchun Chen;Shaorong Gao;Silong Sun;Yongyong Shi;Baoxue Ge |
| 3 | Host-mediated ubiquitination of a mycobacterial protein suppresses immunity | 期刊论文 | Wang L;Wu J;Li J;Yang H;Tang T;Liang H;Zuo M;Wang J;Liu H;Liu F;Chen J;Liu Z;Wang Y;Peng C;Wu X;Zheng R;Huang X;Ran Y;Rao Z;Ge B |
| 4 | 化合物 AG120 或其药学上可接受的盐在制备预防或治疗结核病的药 物中的用途 | 专利 | 戈宝学;陈建霞;刘峰;刘海鹏;李蒿蒿;王菲;刘忠华;唐芬;黄晓辰;王洁 |
| 5 | Airway acidification impaired host defense against Pseudomonas aeruginosa infection by promoting type 1 interferon β response. | 期刊论文 | Yang Liu;Ying-Zhou Xie;Yi-Han Shi;Ling Yang;Xiao-Yang Chen;Ling-Wei Wang;Jie-Ming Qu;Dong Weng;Xiao-Jian Wang;Hai-Peng Liu;Bao-Xue Ge;Jin-Fu Xu |
| 6 | PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1 | 期刊论文 | Lin Wang;Yilong Zhou;Zijuan Chen;Lei Sun;Juehui Wu;Haohao Li;Feng Liu;Fei Wang;Chunfu Yang;Juhao Yang;Qibin Leng;Qingli Zhang;Ajing Xu;Lisong Shen;Jinqiao Sun;Dianqing Wu;Caiyun Fang;Haojie Lu;Dapeng Yan;Baoxue Ge |
| 7 | Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation | 期刊论文 | Zheng Ruijuan;Liu Haipeng;Zhou Yilong;Yan Dapeng;Chen Jianxia;Ma Dapeng;Feng Yonghong;Qin Lianhua;Liu Feng;Huang Xiaochen;Wang Jie;Ge Baoxue |
| 8 | Lysine acetylation of DosR regulates the hypoxia response of Mycobacterium tuberculosis | 期刊论文 | Hua Yang;Wei Sha;Zhonghua Liu;Tianqi Tang;Haipeng Liu;Lianhua Qin;Zhenling Cui;Jianxia Chen;Feng Liu;Ruijuan Zheng;Xiaochen Huang;Jie Wang;Yonghong Feng;Baoxue Ge |
| 9 | C24H24N6O2S3 在制备抗结核菌药物中的用途 | 专利 | 戈宝学;陈建霞;刘峰;刘海鹏;李蒿蒿;王菲;刘忠华;唐芬;黄晓辰;王洁 |
| 10 | 一种用于辅助判断肺结核 病理损伤和/或预后转归的生物学标志物 | 专利 | 刘海鹏;戈宝学;王鹏;陈建霞;刘忠华;范琳 |
| 11 | Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS. | 期刊论文 | Fei Wang;Mengmeng Zhao;Boran Chang;Yilong Zhou;Xiangyang Wu;Mingtong Ma;Siyu Liu;Yajuan Cao;Mengge Zheng;Yifang Dang;Junfang Xu;Li Chen;Tianhao Liu;Fen Tang;Yefei Ren;Zhu Xu;Zhiyong Mao;Kai Huang;Minhua Luo;Jingsong Li;Haipeng Liu;Baoxue Ge |
| 12 | Oxidization of TGFβ-activated kinase by MPT53 is required for immunity to Mycobacterium tuberculosis | 期刊论文 | Wang L;Liu Z;Wang J;Liu H;Wu J;Tang T;Li H;Yang H;Qin L;Ma D;Chen J;Liu F;Wang P;Zheng R;Song P;Zhou Y;Cui Z;Wu X;Huang X;Liang H;Zhang S;Cao J;Wu C;Chen Y;Su D;Chen X;Zeng G;Ge B |
| 13 | miRNAs in immune responses to Mycobacterium tuberculosis infection | 期刊论文 | Yang Tianshu;Ge Baoxue |
| 14 | New insights into the evasion of host innate immunity by Mycobacterium tuberculosis | 期刊论文 | Chai Qiyao;Wang Lin;Liu Cuihua;Ge Baoxue |
| 15 | The multifaceted functions of cGAS | 期刊论文 | Haipeng Liu;Fei Wang;Yajuan Cao;Yifang Dang;Baoxue Ge |
查看更多信息请先登录或注册
