Granulins调控尘肺炎性反应与纤维化的作用机制研究
81773375
2017
H3002.职业卫生与职业病学
姚于勤
面上项目
研究员
四川大学
60万元
矽肺;肺纤维化;抗肺纤维化;尘肺;抗体靶向治疗
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Comparative RNA-Seq transcriptome analysis on silica induced pulmonary inflammation and fibrosis in mice silicosis model | 期刊论文 | Chen Jiayi;Yao Yuqin;Su Xiaolan;Shi Ying;Song Xuejiao;Xie Linshen;You Jia;Tian Liantian;Yang Luo;Fang Aiping;Xiong Jingyuan |
| 2 | Expression of SUMO1P3 Compared with SUMO1 is an Independent Predictor of Patient Outcome in Lung Adenocarcinoma | 期刊论文 | Su Xiaolan;Wan Yang;Xie Linshen;Lin Xiufang;Zhao Hongwen;Ju Xiao;Fang Aiping |
| 3 | The pharmacodynamic and differential gene expression analysis of PPAR α/δ agonist GFT505 in CDAHFD-induced NASH model | 期刊论文 | Liu Linfu;Liu Chuang;Zhao Manyu;Zhang Qianru;Lu Ying;Liu Ping;Yang Hua;Yang Jinliang;Chen Xiaoxin;Yao Yuqin |
| 4 | Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site | 期刊论文 | Lai Qinhuai;Wang Yuxi;Wang Ruixue;Lai Weirong;Tang Liangze;Tao Yiran;Liu Yu;Zhang Ruirui;Huang Luyi;Xiang Haotian;Zeng Shaoxue;Gou Lantu;Chen Hao;Yao Yuqin;Yang Jinliang |
| 5 | The antifibrotic effect and mechanism of a novel tyrosine kinase inhibitor, ZSP1603, in preclinical models of pulmonary fibrosis | 期刊论文 | Liu Z-W;Zhao M-Y;Su X-L;Ye T-H;Zhuang Y-J;Zhang Y.;Zhang Z-Z;Yang J-L;Chen L-J;Long C-F;Yao Y-Q;Chen X-X |
| 6 | High ECT2 expression is an independent prognostic factor for poor overall survival and recurrence-free survival in non-small cell lung adenocarcinoma | 期刊论文 | Zhou Shijie;Wang Ping;Su Xiaolan;Chen Jingxia;Chen Hongfen;Yang Hanbing;Fang Aiping;Xie Linshen;Yao Yuqin;Yang Jinliang |
| 7 | Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH | 期刊论文 | Lu Ying;Su Xiaolan;Zhao Manyu;Zhang Qianru;Liu Chuang;Lai Qinhuai;Wu Sijia;Fang Aiping;Yang Jinliang;Chen Xiaoxin;Yao Yuqin |
| 8 | RAMP3 is a prognostic indicator of liver cancer and might reduce the adverse effect of TP53 mutation on survival | 期刊论文 | Fang Aiping;Zhou Shijie;Su Xiaolan;Liu Chuang;Chen Xiaoxin;Wan Yang;Lei Xiaohong;Xie Linshen;Jia Yiping;Wang Wenzhi;Yang Luo;Song Xuejiao;Yao Yuqin |
| 9 | Design, synthesis and pharmacological evaluation of 4-(3-chloro-4-(3-cyclopropylthioureido)-2-fluorophenoxy)-7-methoxyquinoline-6-carboxamide (WXFL-152): a novel triple-angiokinase inhibitor for cancer therapy | 期刊论文 | Yuqin Yao;Zhuowei Liu;Manyu Zhao;Zhengxia Chen;Peng Li;Yang Zhang;Yuxi Wang;Chengjian Zhao;Chaofeng Long;Xiaoxin Chen;Jinliang Yang |
| 10 | 颗粒蛋白前体在矽肺模型中的表达及其对肺成纤维细胞增殖与分化的影响 | 期刊论文 | 王梦祝;赵曼羽;陈晴;钱蕊;赵钐杉;鲍其雪;杜文;姚于勤;张本 |
| 11 | Preparation and anti-cancer evaluation of promiximab-MMAE, an anti-CD56 antibody drug conjugate, in small cell lung cancer cell line xenograft models | 期刊论文 | Yu Lin;Yao Yuqin;Wang Yuxi;Zhou Shijie;Lai Qinhuai;Lu Ying;Liu Yu;Zhang Ruirui;Wang Ruixue;Liu Chuang;Gou Lantu;Chen Xiaoxin;Yu Yamei;Chen Qiang;Yang Jinliang |
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