靶向淋巴结内树突状细胞的疫苗递送系统用于类风湿性关节炎的治疗
81872814
2018
H3408.药剂学
孙逊
面上项目
教授
四川大学
57万元
树突状细胞;类风湿性关节炎;疫苗递送系统;淋巴结;免疫耐受
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Targeting Lymphoid Tissues to Promote Immune Tolerance | 期刊论文 | Xiao Yan Chen;Guang Sheng Du;Xun Sun |
| 2 | 免疫调节性纳米制剂的研究进展 | 期刊论文 | 李成龙;陈小燕;孙逊 |
| 3 | Whole-Cell-Mimicking Carrier-Free Nanovaccines Amplify Immune Responses Against Cancer and Bacterial Infection | 期刊论文 | Ming Qin;Conor O'Mahony;Nan Qiao;Zhaofei Guo;Min Jiang;Chunting He;Shuting Bai;Penghui He;Yanhua Xu;Hairui Wang;Tao Gong;Zhirong Zhang;Xun Sun |
| 4 | Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy | 期刊论文 | Shuting Bai;Hao Jiang;Yuanshuai Song;Yining Zhu;Ming Qin;Chunting He;Guangsheng Du;Xun Sun |
| 5 | Nanovaccines Mediated Subcutis-to-Intestine Cascade for Improved Protection against Intestinal Infections | 期刊论文 | Zhong Xiaofang;Du Guangsheng;Wang Xuanyu;Ou Yangsen;Wang Hairui;Zhu Yining;Hao Xinyan;Xie Zhiqiang;Zhang Yuandong;Gong Tao;Zhang Zhirong;Sun Xun |
| 6 | Nanomedicines based on nanoscale metal-organic frameworks for cancer immunotherapy | 期刊论文 | Xiao-fang Zhong;Xun Sun |
| 7 | 一种基于微乳的疫苗递送系统及其制备方法和应用 | 专利 | 孙逊;陈正军;龚涛;张志荣 |
| 8 | The pore size of mesoporous silica nanoparticles regulates their antigen delivery efficiency | 期刊论文 | Xiaoyu Hong;Xiaofang Zhong;Guangsheng Du;Yingying Hou;Yunting Zhang;Zhirong Zhang;Tao Gong;Ling Zhang;Xun Sun |
| 9 | Engineering a sustained release vaccine with a pathogen-mimicking manner for robust and durable immune responses | 期刊论文 | Hou Yingying;Liu Rong;Hong Xiaoyu;Zhang Yunting;Bai Shuting;Luo Xianjin;Zhang Yuandong;Gong Tao;Zhang Zhirong;Sun Xun |
| 10 | Single-shot AAV-vectored vaccine against SARS-CoV-2 with fast and long-lasting immunity | 期刊论文 | Fuhua Wu;Shuang Luo;Yongshun Zhang;Yangsen Ou;Hairui Wang;Zhaofei Guo;Chunting He;Shuting Bai;Penghui He;Min Jiang;Xiaoyan Chen;Guangsheng Du;Xun Sun |
| 11 | Nanoparticles with rough surface improve the therapeutic effect of photothermal immunotherapy against melanoma | 期刊论文 | Xue Jiao;Zhu Yining;Bai Shuting;He Chunting;Du Guangsheng;Zhang Yuandong;Zhong Yao;Chen Wenfei;Wang Hairui;Sun Xun |
| 12 | Advanced oral vaccine delivery strategies for improving the immunity | 期刊论文 | Yuandong Zhang;Man Li;Guangsheng Du;Xiaoyan Chen;Xun Sun |
| 13 | An antigen self-assembled and dendritic cell-targeted nanovaccine for enhanced immunity against cancer | 期刊论文 | Yunting Zhang;Min Jiang;Guangsheng Du;Xiaofang Zhong;Chunting He;Ming Qin;Yingying Hou;Rong Liu;Xun Sun |
| 14 | Recombinant lactic acid bacteria as promising vectors for mucosal vaccination | 期刊论文 | Nan Qiao;Conor O'Mahony;Xiaofang Zhong;Xun Sun |
| 15 | Nanoemulsions Target to Ectopic Lymphoids in Inflamed Joints to Restore Immune Tolerance in Rheumatoid Arthritis | 期刊论文 | Chenglong Li;Xiaoyan Chen;Xianjin Luo;Hairui Wang;Yining Zhu;Guangshen Du;Wenfei Chen;Zhengjun Chen;Xinyan Hao;Zhirong Zhang;Xun Sun |
| 16 | Smart combination of aluminum hydroxide and MF59 to induce strong cellular immune responses | 期刊论文 | Zhengjun Chen;Xinyan Hao;Hairui Wang;Xiaofang Zhong;Xiaoyan Chen;Yuanhao Zhao;Yuandong Zhang;Guangsheng Du;Xun Sun |
| 17 | Restoring immunological tolerance in established experimental arthritis by combinatorial citrullinated peptides and immunomodulatory signals | 期刊论文 | Xiaoyan Chen;Guangsheng Du;Shuting Bai;Liu Dijia;Chenglong Li;Yingying Hou;Yuandong Zhang;Zhirong Zhang;Tao Gong;Yao Fu;Massimo Bottini;Xun Sun |
| 18 | Co-delivery of antigen and dual adjuvants by aluminum hydroxide nanoparticles for enhanced immune responses | 期刊论文 | Yingying Hou;Ying Wang;Yao Tang;Zixuan Zhou;Lu Tan;Tao Gong;Ling Zhang;Xun Sun |
| 19 | Tumor Antigen-Based Nanovaccines for Cancer Immunotherapy: A Review | 期刊论文 | Jiaxuan Zhao;Guangsheng Du;Xun Sun |
| 20 | Optimization of an mRNA vaccine assisted with cyclodextrin-polyethyleneimine conjugates | 期刊论文 | Lu Tan;Tao Zheng;Man Li;Xiaofang Zhong;Yao Tang;Ming Qin;Xun Sun |
| 21 | The effects of all-trans retinoic acid on immune cells and its formulation design for vaccines | 期刊论文 | Xinyan Hao;Xiaofang Zhong;Xun Sun |
| 22 | Rapid development of a subunit nano-vaccine against drug-resistant Pseudomonas aeruginosa with effective cross-protection | 期刊论文 | Zhaofei Guo;Yining Zhu;Guangsheng Du;Ming Qin;Chunting He;Penghui He;Yuanshuai Song;Wenfei Chen;Shuting Bai;Fuhua Wu;Nan Qiao;Min Jiang;Xianjin Luo;Yuandong Zhang;Tao Gong;Zhirong Zhang;Xun Sun |
| 23 | Dual drugs decorated bacteria irradiate deep hypoxic tumor and arouse strong immune responses | 期刊论文 | Wenfei Chen;Chunting He;Nan Qiao;Zhaofei Guo;Shilong Hu;Yuanshuai Song;Hairui Wang;Zhirong Zhang;Bowen Ke;Xun Sun |
| 24 | Recent Advances in the Noninvasive Delivery of mRNA | 期刊论文 | Ming Qin;Conor O'Mahony;Xun Sun |
| 25 | An aluminum adjuvant-integrated nano-MOF as antigen delivery system to induce strong HUMORAL and cellular immune responses | 期刊论文 | Xiaofang Zhong;Yunting Zhang;Lu Tan;Tao Zheng;Yingying Hou;Xiaoyu Hong;Guangsheng Du;Xiaoyan Chen;Yuandong Zhang;Xun Sun |
| 26 | 一种亲水性抗原和/或疏水性抗原疫苗递送系统及其制备方法 | 专利 | 孙逊;张志荣;洪小玉;郭兆飞;龚涛 |
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