上皮炎性衰老通过NLRC4/TLR5调控伴糖尿病牙周炎发生发展的研究

81870779
2018
H1504.牙周及口腔黏膜疾病
王琪
面上项目
教授
四川大学
58万元
炎性衰老;TLR5;NLRC4;牙龈上皮;伴糖尿病牙周炎
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 全程质控视角下口腔医疗器械临床试验高质量管理对策 期刊论文 王琪;梁新华
2 半导体激光在种植体周围病中的应用及研究进展 期刊论文 朱康剑;王琪
3 Diabetes fuels periodontal lesions via GLUT1-driven macrophage inflammaging 期刊论文 Wang Qian;Nie Lulingxiao;Zhao Pengfei;Zhou Xinyi;Ding Yi;Chen Qianming;Wang Qi
4 Effect of adjunctive diode laser in the non-surgical periodontal treatment in patients with diabetes mellitus: a systematic review and meta-analysis. 期刊论文 Pengfei Zhao;Xiuxiu Song;Qian Wang;Peng Zhang;Lulingxiao Nie;Yi Ding;Qi Wang
5 Single-Cell Transcriptomic Atlas of Gingival Mucosa in Type 2 Diabetes 期刊论文 Q. Wang;W. Lin;X. Zhou;K. Lei;R. Xu;X. Zhang;Q. Xiong;R. Sheng;W. Song;W. Liu;Q. Wang;Quan Yuan
6 25-Hydroxyvitamin D3 positively regulates periodontal inflammaging via T SOCS3/STAT signaling in diabetic mice 期刊论文 Qian Wang;Xinyi Zhou;Peng Zhang;Pengfei Zhao;Lulingxiao Nie;Ning Ji;Yi Ding;Qi Wang
7 lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases 期刊论文 Lulingxiao Nie;Peng Zhang;Qian Wang;Xinyi Zhou;Qi Wang
8 Biological Functions of Diallyl Disulfide, a Garlic-Derived Natural Organic Sulfur Compound 期刊论文 Xiuxiu Song;Ziqi Yue;Lulingxiao Nie;Pengfei Zhao;Kangjian Zhu;Qi Wang
9 基于病案的口腔医学临床思维培养 专著 张凌琳;华成舸;郑庆华;王剑;江潞;王琪
10 Senescence-associated secretory phenotype and its impact on oral immune homeostasis 期刊论文 Ziqi Yue;Lulingxiao Nie;Pengfei Zhao;Ning Ji;Ga Liao;Qi Wang
11 高糖相关炎性衰老影响牙龈上皮屏障功能的研究 会议论文 张鹏;王琪;梁星;岳子琪;王倩;周欣奕
12 二甲双胍通过抑制炎性小体改善伴糖尿病牙周组织炎症水平的研究 会议论文 王倩;张鹏;周欣奕;赵鹏飞;聂鲁凌霄;丁一;王琪
13 Tissue-Resident Macrophage Inflammaging Aggravates Homeostasis Dysregulation in Age-Related Diseases 期刊论文 Ziqi Yue;Luningxiao Nie;Peng Zhang;Qin Chen;Qingguo Lv;Qi Wang
14 伴糖尿病牙周炎的治疗进展 期刊论文 丁一;王琪
15 基于全过程管理视角的口腔专业本科教学质量控制对策 期刊论文 赵鹏飞;郑巧;刘孝宇;张凌琳;王琪
16 Hyperglycemia accelerates inflammaging in the gingival epithelium through inflammasomes activation 期刊论文 Peng Zhang;Boyao Lu;Rui Zhu;Dawei Yang;Weiqing Liu;Qian Wang;Ning Ji;Qianming Chen;Yi Ding;Xing Liang;Qi Wang
17 Metformin ameliorates the NLPP3 inflammasome mediated pyroptosis by inhibiting the expression of NEK7 in diabetic periodontitis 期刊论文 Zhou Xinyi;Wang Qian;Nie Lulingxiao;Zhang Peng;Zhao Pengfei;Yuan Quan;Ji Ning;Ding Yi;Wang Qi
18 伴糖尿病患者种植骨缺损的病因及治疗的研究进展 期刊论文 赵鹏飞;王琪
19 Relationship between serum 25‐hydroxyvitamin D3 levels and severity of chronic periodontitis in type 2 diabetic patients: A cross‐sectional study 期刊论文 Qian Wang;Xinyi Zhou;Jingjing Jiang;Peng Zhang;Sisi Xia;Yi Ding;Qi Wang
20 Relationship between circulating senescence‐associated secretory phenotype levels and severity of type 2 diabetes‐associated periodontitis: A cross‐sectional study 期刊论文 Xiuxiu Song;Ziqi Yue;Linli Fan;Haonan Zou;Pengfei Zhao;Lulingxiao Nie;Kangjian Zhu;Jingjing Jiang;Qingguo Lv;Qi Wang
21 高糖水平下牙周组织的形态与免疫特征 期刊论文 孙乐章;王琪
22 口腔修复科诊疗与操作常规 专著 周学东;于海洋;熊芳;甘雪琦;王琪;高姗姗
23 Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation. 期刊论文 Peng Zhang;Qian Wang;Lulingxiao Nie;Rui Zhu;Xinyi Zhou;Pengfei Zhao;Ning Ji;Xing Liang;Yi Ding;Quan Yuan;Qi Wang
24 Efficacy of adjunctive photodynamic therapy and lasers in the non-surgical periodontal treatment: a Bayesian network meta-analysis. 期刊论文 Pengfei Zhao;Xiuxiu Song;Lulingxiao Nie;Qian Wang;Peng Zhang;Yi Ding;Qi Wang
25 具有成骨-抗炎-血糖三维响应结构的牙种植体及其制备方法 专利 王琪;王倩;张鹏;周欣奕;赵鹏飞;聂鲁凌霄;梁星;丁一
26 半导体激光辅助牙周非手术治疗伴糖尿病牙周炎疗效的Meta分析 会议论文 赵鹏飞;宋秀秀;丁一;王琪
27 Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7(Nek7) expression 期刊论文 Xinyi Zhou;Peng Zhang;Qian Wang;Ning Ji;Sisi Xia;Yi Ding;Qi Wang
28 Diabetes induces macrophage dysfunction through cytoplasmic dsDNA/AIM2 associated pyroptosis 期刊论文 Lulingxiao Nie;PengFei Zhao;Ziqi Yue;Peng Zhang;Ning Ji;Qianming Chen;Qi Wang
29 铒激光辅助牙冠延长术应用于美学区修复1例 会议论文 宋秀秀;张雨薇;丁一;王琪
30 Hyperglycaemia‐associated macrophage pyroptosis accelerates periodontal inflamm‐aging 期刊论文 Pengfei Zhao;Ziqi Yue;Lulingxiao Nie;Zhihao Zhao;Qian Wang;Jiao Chen;Qi Wang
31 Clinical efficacy of chlorhexidine as an adjunct to mechanical therapy of peri-implant disease: a systematic review and meta-analysis. 期刊论文 Pengfei Zhao;Qian Wang;Peng Zhang;Xinyi Zhou;Lulingxiao Nie;Xing Liang;Yi Ding;Qi Wang
32 基于 SASP 的糖尿病口腔炎症性疾病的患病风险预测方法及装置 专利 王琪;邹浩南;范林莉;朱康剑;岳子琪;蒋晶晶;孙乐章
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