肺组织靶向性微管抑制剂SKLB060肺部特异性靶点鉴定
序号 | 标题 | 类型 | 作者 |
---|---|---|---|
1 | Covalent modification of Cys-239 in -tubulin by small molecules as a strategy to promote tubulin heterodimer degradation | 期刊论文 | 杨建洪;黎勇;闫伟;李为民;邱强;叶昊宇;陈俐娟 |
2 | Anti-Tumor Study of H6, a 4-Substituted Coumarins Derivative, Loaded Biodegradable Self-Assembly Nano-Micelles In Vitro and In Vivo | 期刊论文 | 朱泽江;苏正盈;杨建洪;刘慧莉;汤明海;胡巧巧;白鹏;温娇琳;何俊;牛挺;陈俐娟 |
3 | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1’s low clinical toxicity | 期刊论文 | 牛璐;杨建洪;闫伟;余亚梅;郑云华;叶昊宇;陈强;陈俐娟 |
4 | Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect | 期刊论文 | 杨建洪;余亚梅;黎勇;闫伟;叶昊宇;牛璐;汤明海;汪周峰;杨壮;裴和颖;魏浩澈;赵旻;温娇琳;杨林玉;欧阳亮;魏于全;陈强;李为民;陈俐娟 |
5 | The Natural Compound Withaferin A Covalently Binds to Cys239 of β-Tubulin to Promote Tubulin Degradation | 期刊论文 | 杨建洪;闫伟;黎勇;牛璐;叶昊宇;陈俐娟 |