基于肿瘤相关成纤维细胞调控的双靶向程序性药物递释系统研究

81703450
2017
H3408.药剂学
李曼
青年科学基金项目
副教授
四川大学
20万元
肿瘤免疫微环境;深层穿透;MMP酶敏感;程序性递药系统;肿瘤相关成纤维细胞屏障
2018-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration 期刊论文 Cun Xingli;Li Man;Wang Shuying;Wang Yifei;Wang Jialing;Lu Zhengze;Yang Ruixin;Tang Xian;Zhang Zhirong;He Qin
2 Tumor-Targeted Chemoimmunotherapy with Immune-Checkpoint Blockade for Enhanced Anti-Melanoma Efficacy 期刊论文 Li Man;Yang Yuting;Xu Chaoqun;Wei Jiaojie;Liu Yingke;Cun Xingli;Yu Qianwen;Tang Xian;Yin Sheng;Zhang Zhirong;He Qin
3 Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle 期刊论文 Xingli Cun;Jiantao Chen;Mengmeng Li;Xuan He;Xian Tang;Rong Guo;Miao Deng;Man Li;Zhirong Zhang;Qin He
4 Multifunctional polymeric micelle-based chemo-immunotherapy with immune checkpoint blockade for efficient treatment of orthotopic and metastatic breast cancer 期刊论文 Wei Jiaojie;Long Yang;Guo Rong;Liu Xinlei;Tang Xian;Rao Jingdong;Yin Sheng;Zhang Zhirong;Li Man;He Qin
5 Enhanced chemo-immunotherapy against melanoma by inhibition of cholesterol esterification in CD8+ T cells 期刊论文 Man Li;Yuting Yang;Jiaojie Wei;Xingli Cun;Zhengze Lu;Yue Qiu;Zhirong Zhang;Qin He
6 PD-L1 knockdown via hybrid micelle promotes paclitaxel induced Cancer-Immunity Cycle for melanoma treatment 期刊论文 Tang Xian;Rao Jingdong;Yin Sheng;Wei Jiaojie;Xia Chunyu;Li Man;Mei Ling;Zhang Zhirong;He Qin
7 Synergistic tumor microenvironment targeting and blood-brain barrier penetration via a pH-responsive dual-ligand strategy for enhanced breast cancer and brain metastasis therapy 期刊论文 Li Man;Shi Kairong;Tang Xian;Wei Jiaojie;Cun Xingli;Long Yang;Zhang Zhirong;He Qin
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