新型结核分枝杆菌选择性抑制剂的构效关系及靶点鉴定研究

81473253
2014
H3506.抗感染药物药理
罗有福
面上项目
研究员
四川大学
65万元
靶点鉴定;双噁唑烷酮;结核分枝杆菌;化学蛋白组学;构效关系
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a] quinoxaline-based scaffold 期刊论文 Ting Wang;Yunxiang Tang;Yang Yang;Qi An;Zitai Sang;Tao Yang;Pingxian Liu;Tianyu Zhang;Yong Deng;Youfu Luo
2 一种NPS-2143用于抗菌的新用途 专利 罗有福;杨涛;魏于全
3 Improving the pharmacokinetics and tissue distribution of pyrinezolid by self-assembled polymeric micelles 期刊论文 Haiyue Long;Xiaoling Li;Zitai Sang;Lan Mei;Tao Yang;Zicheng Li;Liangxue Zhou;Yu Zheng;Gu He;Gang Guo;Zhenling Wang;Yong Deng;Youfu Luo
4 色瑞替尼的抗菌新用途 专利 罗有福;杨涛;魏于全
5 一种吲哚-2-酮类化合物在抗持留菌方面的用途 专利 罗有福;杨涛;魏于全
6 Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis 期刊论文 Pingxian Liu;Yang Yang;Yuan Ju;Yunxiang Tang;Zitai Sang;Lijuan Chen;Tao Yang;Qi An;Tianyu Zhang;Youfu Luo
7 Discovery of a Teraryl Oxazolidinone Compound (S)‑N‑((3-(3-Fluoro- 4-(4-(pyridin-2-yl)‑1H‑pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)- methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies 期刊论文 Tao Yang;Gong Chen;Zitai Sang;Yuanyuan Liu;Xiaoyan Yang;Ying Chang;Haiyue Long;Wei Ang;Jianying Tang;Zhenling Wang;Guobo Li;Shengyong Yang;Jingren Zhang;Yuquan Wei;Youfu Luo
8 Design and synthesis of novel pyrimidine derivatives as potent antitubercular agents 期刊论文 Pingxian Liu;Yang Yang;Yunxiang Tang;Tao Yang;Zitai Sang;Zhiyong Liu;Tianyu Zhang;Youfu Luo
9 一种吲哚-2-酮类化合物在抗菌方面的用途 专利 罗有福;杨涛;魏于全
10 一种4-氟-2-甲基吲哚类化合物的抗菌新用途 专利 罗有福
11 A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3) 期刊论文 Chungen Li;Caili Chen;Qi An;Tao Yang;Zitai Sang;Yang Yang;Yuan Ju;Aiping Tong;Youfu Luo
12 Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria 期刊论文 Yuanzheng Zhou;Yuan Ju;Yang Yang;Zitai Sang;Zhenling Wang;Gu He;Tao Yang;Youfu Luo
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