肿瘤耐药相关的蛋白质氧化还原修饰及信号调控
81430071
2014
H18.肿瘤学
黄灿华
重点项目
教授
四川大学
340万元
耐药;C25_其它肿瘤;氧化应激;翻译后修饰;药物靶标
2015-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | PDLIM1 stabilizes the E-cadherin/Beta catenin complex to prevent epithelial mesenchymaltransition and metastatic potential of colorectal cancer cells | 期刊论文 | Hai-Ning Chen;Kefei Yuan;Na Xie;Kui Wang;Zhao Huang;Yan Chen;Qianhui Dou;Min Wu;Edouard C. Nice;Zong-Guang Zhou;Canhua Huang |
| 2 | Tissue and plasma proteomics for early stage cancer detection | 期刊论文 | Peng L;Cantor DI;Huang C;Wang K;Baker MS;Nice EC |
| 3 | A novel role for ketoconazole inhepatocellular carcinoma treatment: linking PTGS2 to mitophagy machinery. | 期刊论文 | Chen H-N;Chen Y;Zhou Z-G;Wei Y;Huang C |
| 4 | Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy | 期刊论文 | Zhang Z;Gao W;Zhou L;Chen Y;Qin S;Zhang L;Liu J;He Y;Lei Y;Chen H-N;Han J;Zhou Z-G;Nice EC;Li C;Huang C;Wei X |
| 5 | Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice | 期刊论文 | Lei Y;Wang K;Li X;Li Y;Feng X;Zhou J;Zhang Z;Huang C;Zhang T |
| 6 | Clinical proteomics-driven precision medicine for targeted cancer therapy: current overview and future perspectives | 期刊论文 | Li Zhou;Kui Wang;Qifu Li;Edouard C. Nice;Haiyuan Zhang;Canhua Huang |
| 7 | Nuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growth | 期刊论文 | Liu Y;Guo JZ;Liu Y;Wang K;Ding W;Wang H;Liu X;Zhou S;Lu XC;Yang HB;Xu C;Gao W;Zhou L;Wang YP;Hu W;Wei Y;Huang C;Lei QY |
| 8 | PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation. | 期刊论文 | Xie Na;Yuan Kefei;Zhou Li;Wang Kui;Chen Hai-Ning;Lei Yunlong;Lan Jiang;Pu Qinqin;Gao Wei;Zhang Lu;Shen Guobo;Li Qifu;Xiao Hengyi;Tang Hong;Xiang Rong;He Mingliang;Feng Pinghui;Nice Edouard C;Wei Yuquan;Zhang Haiyuan;Yang Jiayin;Huang Canhua |
| 9 | Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer. | 期刊论文 | Dou Qianhui;Chen Hai-Ning;Wang Kui;Yuan Kefei;Lei Yunlong;Li Kai;Lan Jiang;Chen Yan;Huang Zhao;Xie Na;Zhang Lu;Xiang Rong;Nice Edouard C;Wei Yuquan;Huang Canhua |
| 10 | High-throughput screening of cellular redox sensors using modern redox proteomics approaches | 期刊论文 | Jingwen Jiang;Kui Wang;Edouard C Nice;Tao Zhang;Canhua Huang |
| 11 | Oncoproteomics: Trials and Tribulations | 期刊论文 | Li Zhou;Qifu Li;Jiandong Wang;Canhua Huang;Edouard C. Nice |
| 12 | Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress | 期刊论文 | Zhang Z;Zhang L;Zhou L;Lei Y;Zhang Y;Huang C |
| 13 | Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis. | 期刊论文 | Li Xuefeng;He Sisi;Zhou Xikun;Ye Yan;Tan Shirui;Zhang Shuang;Li Rongpeng;Yu Min;Jundt Michael C;Hidebrand Alec;Wang Yongsheng;Li Guoping;Huang Canhua;Wu Min |
| 14 | Pseudomonas aeruginosa infection augments inflammation through miR-301b repression of c-Myb-mediated immune activation and infiltration. | 期刊论文 | Li Xuefeng;He Sisi;Li Rongpeng;Zhou Xikun;Zhang Shuang;Yu Min;Ye Yan;Wang Yongsheng;Huang Canhua;Wu Min |
| 15 | 酮康唑在制备治疗肝癌的药物中的用途 | 专利 | 黄灿华;陈海宁;陈燕;王魁;张露 |
| 16 | Molecular insights into cancerdrug resistance from a proteomics perspective | 期刊论文 | An Y;Zhou L;Huang Z;Nice EC;Zhang H;Huang C |
| 17 | Redox regulation of inflammation: old elements, a new story | 期刊论文 | Lei Y; Wang K; Nice EC; Huang C |
| 18 | Redox Signaling:Potential Arbitrator of Autophagy and Apoptosis in Therapeutic Response | 期刊论文 | Lu Zhang;Kui Wang;Yunlong Lei;Qifu Li;Edouard C Nice;Canhua Huang |
| 19 | Redox regulation in tumor cell epithelial-mesenchymal transition: molecular basis and therapeutic strategy | 期刊论文 | Jiang Jing Wen;Wang Kui;Chen Yan;Chen Haining;Nice Edouard C;Huang Canhua |
| 20 | Cancer drug resistance: redox resetting renders a way | 期刊论文 | Liu Yuan;Li Qifu;Zhou Li;Xie Na;Nice Edouard C;Zhang Haiyuan;Huang Canhua;Lei Yunlong |
| 21 | Tubeimoside I induces accumulation of impaired autophagolysosome against cervical cancer cells by both initiating autophagy and inhibiting lysosomal function | 期刊论文 | Feng X;Zhou J;Li J;Hou X;Li L;Chen Y;Fu S;Zhou L;Li C;Lei Y |
| 22 | Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer. | 期刊论文 | Wang Kui;Gao Wei;Dou Qianhui;Chen Haining;Li Qifu;Nice Edouard C;Huang Canhua |
| 23 | Redox proteomics screening cellular factors associated with oxidative stress in hepatocarcinogenesis | 期刊论文 | Li Zhou;Ji Wen;Zhao Huang;Edouard C. Nice;Canhua Huang;Haiyuan Zhang;Qifu Li |
| 24 | Brefeldin A inhibits colorectal cancer growth by triggering Bip/Akt-regulated autophagy | 期刊论文 | Zhou L;Gao W;Wang K;Huang Z;Zhang L;Zhang Z;Zhou J;Nice EC;Huang C |
| 25 | MCT1 relieves osimertinib-induced CRC suppression by promoting autophagy through the LKB1/AMPK signaling. | 期刊论文 | Jin P;Jiang J;Xie N;Zhou L;Huang Z;Zhang L;Qin S;Fu S;Peng L;Gao W;Li B;Lei Y;Nice EC;Li C;Shao J;Xie K |
| 26 | Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux | 期刊论文 | Kui Wang;Tao Zhang;Yunlong Lei;Xuefeng Li;Jingwen Jiang;Jiang Lan;Yuan Liu;Wei Gao;Na Xie;Qiang Chen;Xiaofeng Zhu;Xiang Liu;Ke Xie;Yong Peng;Edouard C Nice;Min Wu;Canhua Huang;Yuquan Wei |
| 27 | Ketoconazole exacerbates mitophagy to induce apoptosis by downregulating cyclooxygenase-2 in hepatocellular carcinoma | 期刊论文 | Chen Y;Chen HN;Wang K;Zhang L;Huang Z;Liu J;Zhang Z;Luo M;Lei Y;Peng Y;Zhou ZG;Wei Y;Huang C |
| 28 | FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 | 期刊论文 | Liu R; Huang S; Lei Y; Zhang T; Wang K; Liu B; Nice EC; Xiang R; Xie K; Li J; Huang C |
| 29 | Pathology, proteomics and the pathway to personalised medicine | 期刊论文 | Ping Jin;Jiang Lan;Kui Wang;Mark S Baker;Canhua Huang;Edouard C Nice |
| 30 | Redox regulation of microRNAs in cancer | 期刊论文 | Jiang Lan;Zhao Huang;Junhong Han;Jichun Shao;Canhua Huang |
| 31 | HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3. | 期刊论文 | Yuan Kefei;Lei Yunlong;Chen Haining;Chen Yi;Zhang Tao;Li Kai;Xie Na;Wang Kui;Feng Xuping;Pu Qinqin;Yang Wenyong;Wu min;Xiang Rong;Nice Edouard. C;Huang Canhua;Wei Yuquan |
| 32 | Targeting Metabolic-Redox Circuits for Cancer Therapy | 期刊论文 | Wang K;Jiang J;Lei Y;Zhou S;Wei Y;Huang C |
| 33 | Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 inglioblastoma | 期刊论文 | Jiang J;Zhang L;Chen H-N;Lei Y;Zhang T;Wang Y;Jin P;Lan J;Zhou L;HuangZ;Li B;Liu Y;Gao W;Xie K;Zhou L;Nice EC;Peng Y;Cao Y;Wei Y;Wang K;Huang C |
| 34 | PDLIM1 inhibits tumor metastasis through activating Hippo signaling in hepatocellular carcinoma | 期刊论文 | Huang Z;Zhou J-K;Wang K;Chen H-N;Qin S;Liu J;Luo M;Chen Y;Jiang J;Zhou L;Zhu L;He J;Li J;Pu W;Gong Y;Li J;Ye Q;Dong D;Hu H;Zhou Z;Dai L;Wei Y;Huang C;Wei X;Peng Y |
| 35 | 瑞戈非尼在制备治疗脑胶质瘤的药物中的用途 | 专利 | 黄灿华;王魁;蒋静文;张露;雷云龙 |
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