细胞发育谱系树比对算法的设计与应用
31871320
2018
C0609.生物大数据解析
杨建荣
面上项目
教授
中山大学
60万元
动物;细胞发育谱系树;细胞类型的进化;比较基因组学;生物信息学新方法
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Dosage sensitivity of X-linked genes in human embryonic single cells | 期刊论文 | Yang Jian Rong;Chen Xiaoshu |
| 2 | The evolution of sex chromosome dosage compensation in animals | 期刊论文 | Chen Jiabi;Wang Menghan;He Xionglei;Yang Jianrong;Chen Xiaoshu |
| 3 | Prediction of Antibiotic Resistance Evolution by Growth Measurement of All Proximal Mutants of Beta-Lactamase | 期刊论文 | Siyuan Feng;Zhuoxing Wu;Wanfei Liang;Xin Zhang;Xiujuan Cai;Jiachen Li;Lujie Liang;Daixi Lin;Nicole Stoesser;Yohei Doi;Lan-lan Zhong;Yan Liu;Yong Xia;Min Dai;Liyan Zhang;Xiaoshu Chen;Jian-Rong Yang;Guo-bao Tian |
| 4 | Expression level is a major modifier of the fitness landscape of a protein coding gene | 期刊论文 | Zhuoxing Wu;Xiujuan Cai;Xin Zhang;Yao Liu;Guo-bao Tian;Jian-Rong Yang;Xiaoshu Chen |
| 5 | Specificity of RNA Folding and its Association with Evolutionarily Adaptive mRNA Secondary Structures | 期刊论文 | Gongwang Yu;Hanbing Zhu;Xiaoshu Chen;Jian-Rong Yang |
| 6 | Bidirectional genetic control of phenotypic heterogeneity and its implication for cancer drug resistance | 期刊论文 | 莫宁;张晓玉;石文俊;余功旺;陈小舒;杨建荣 |
| 7 | Alignment of Cell Lineage Trees Elucidates Genetic Programs for the Development and Evolution of Cell Types | 期刊论文 | Yuan Meng;Yang Xujiang;Lin Jinghua;Cao Xiaolong;Chen Feng;Zhang Xiaoyu;Li Zizhang;Zheng Guifeng;Wang Xueqin;Chen Xiaoshu;Yang Jian-Rong |
| 8 | Dissimilation of synonymous codon usage bias in virus-host coevolution due to translational selection. | 期刊论文 | Feng Chen;Peng Wu;Shuyun Deng;Heng Zhang;Yutong Hou;Zheng Hu;Jianzhi Zhang;Xiaoshu Chen;Jian-Rong Yang |
| 9 | Lack of evolutionary convergence in multiple primary lung cancer suggests insufficient specificity of personalized therapy | 期刊论文 | Hua Cheng;Ziyan Guo;Xiaoyu Zhang;Xiao-Jin Wang;Zizhang Li;Wen-Wen Huo;Hong-Cheng Zhong;Xiao-Jian Li;Xiang-Wen Wu;Wen-Hao Li;Zhuo-Wen Chen;Tian-Chi Wu;Xiang-Feng Gan;Bei-Long Zhong;Vassily A. Lyubetsky;Leonid Yu. Rusin;Junnan Yang;Qiyi Zhao;Qing-Dong Cao;Jian-Rong Yang |
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