一种自组装靶向FGFR阳离子脂质体用于基因和化疗药物传递系统的构建及抗肿瘤作用研究

81071251
2010
H2809.医用生物材料与仿生材料
陈俐娟
面上项目
教授
四川大学
35万元
靶向肿瘤细胞和肿瘤血管;多肽;抗肿瘤;靶向阳离子脂质体;tbFGF
2011-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Intravenous liposomal delivery of the short hairpin RNAs against Plk1 controls the growth of established human hepatocellular carcinoma 期刊论文 Wei, Yuquan|Jiang, Qingyuan|Yang, Yang|Zhang, Shuang|Ma, Yongping|Xie, Gang|Chen, Xiang|Qian, Zhiyong|Wen, Yanjun|
2 Truncated bFGF-Mediated Cationic Liposomal Paclitaxel for Tumor-Targeted Drug Delivery: Improved Pharmacokinetics and Biodistribution in Tumor-Bearing Mice 期刊论文 Wang, Xianhuo|Deng, Linyu|Chen, Xiang|Pei, Heying|Cai, Lulu|Zhao, Xia|Wei, Yuquan|Chen, Lijuan|
3 Improved solubility and pharmacokinetics of PEGylated liposomal honokiol and human plasma protein binding ability of honokiol 期刊论文 Chen, Li-Juan|Cai, Lu-Lu|Zhang, Xiao-Yan|Deng, Lin-Yu|Zheng, Hao|Deng, Chong-Yang|Wen, Jiao-Lin|Zhao, Xia|Wei, Yu-Quan|
4 Honokiol Crosses BBB and BCSFB, and Inhibits Brain Tumor Growth in Rat 9L Intracerebral Gliosarcoma Model and Human U251 Xenograft Glioma Model 期刊论文 Chen, Lijuan|Duan, Xingmei|Yang, Guangli|Zhang, Xiaoyan|Deng, Linyu|Zheng, Hao|Deng, Chongyang|Wen, Jiaolin|Wang, Ning|
5 RNA interference-mediated silencing of focal adhesion kinase inhibits growth of human malignant glioma xenograft in nude mice 期刊论文 Deng, Hong-Xin|Ma, Yong-Ping|Yang, Yang|Zhang, Na|Wang, Wei|Liu, Sheng-Yong|Chen, Li-Juan|Jiang, Yu|Zhao, Xia|
6 一种查尔酮化合物通过ROS线粒体通路的抗凋亡机制及其体内抑制肿瘤效果研究 期刊论文 陈俐娟|
7 Treating colon cancer with a suicide gene delivered by self-assembled cationic MPEG-PCL micelles 期刊论文 Duan, XingMei|Wang, Pan|Men, Ke|Gao, Xiang|Huang, MeiJuan|Gou, MaLing|Chen, LiJuan|Qian, ZhiYong|Wei, YuQuan|
8 A novel truncated basic fibroblast growth factor fragment-conjugated poly (ethylene glycol)-cholesterol amphiphilic polymeric drug delivery system for targeting to the FGFR-overexpressing tumor cells 期刊论文 Cai, Lulu|Qiu, Neng|Li, Xia|Luo, Kaili|Chen, Xiang|Yang, Li|He, Gu|Wei, Yuquan|Chen, Lijuan|
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