骨修复材料移植早期的细胞应激与稳态维持对骨形成的作用机理研究
31430030
2014
C1002.生物材料与生物效应
邹学农
重点项目
教授
中山大学
310万元
骨修复材料;应激与稳态;表观遗传修饰;骨形成;应激转录因子
2015-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | C3H10T1/2成软骨分化过程中miR-19a与CCND1的表达及调控 | 期刊论文 | 龚铭;周治宇;代学俊;高蔓蔓;罗嘉全;黄胜;李亮平;邹学农 |
| 2 | 一种炎症响应型引导组织再生膜的制备方法 | 专利 | 石锐;田伟 |
| 3 | CTHRC1 induces non-small cell lung cancer (NSCLC) invasion through upregulating MMP-7/MMP-9 | 期刊论文 | He Weiling;Zhang Hui;Wang Yuefeng;Zhou Yanbin;Luo Yifeng;Cui Yongmei;Jiang Neng;Jiang Wenting;Wang Han;Xu Di;Li Shuhua;Wang Zhuo;Chen Yangshan;Sun Yu;Zhang Yang;Tseng Hsian Rong;Zou Xuenong;Wang Liantang;Ke Zunfu |
| 4 | miR-582-3p and miR-582-5p Suppress Prostate Cancer Metastasis to Bone by Repressing TGF-beta Signaling. | 期刊论文 | Huang Shuai;Zou Changye;Tang Yubo;Wa Qingde;Peng Xinsheng;Chen Xiao;Yang Chunxiao;Ren Dong;Huang Yan;Liao Zhuangwen;Huang Sheng;Zou Xuenong;Pan Jincheng |
| 5 | A New Diagnostic Medium for Cervical Spondylotic Myelopathy: Dynamic Somatosensory Evoked Potentials | 期刊论文 | Qihua Qi;Sheng Huang;Zemin Ling;Yan Chen;Hao Hu;Ping Zhan;Bin Zhang;Xuenong Zou;Xinsheng Peng |
| 6 | Methylation-mediated silencing of miR-124 facilitates chondrogenesis by targeting NFATc1 under hypoxic conditions | 期刊论文 | Gong Ming;Liang Tangzhao;Jin Song;Dai Xuejun;Zhou Zhiyu;Gao Manman;Huang Sheng;Luo Jiaquan;Zou Lijin;Zou Xuenong |
| 7 | H_2O_2下调miR-21对MC3T3-E1细胞成骨分化影响的研究 | 期刊论文 | 彭建强;黄年盛;黄胜;李亮平;凌泽民;靳松;黄爱军;林昆;邹学农 |
| 8 | 一种多层同轴纤维骨修复膜材料及其制备方法 | 专利 | 石锐;池骋;张静爽;李伟阳;田伟 |
| 9 | Opposite Regulation of Chondrogenesis and Angiogenesis in Cartilage Repair ECM Materials under Hypoxia | 期刊论文 | Chen Shaoming;Gao Manman;Zhou Zhiyu;Liang Jiabi;Gong Ming;Dai Xuejun;Liang Tangzhao;Ye Jiacheng;Wu Gang;Zou Lijin;Wang Yingjun;Zou Xuenong |
| 10 | Auxiliary diagnostic value of p16 amplification combined with the detection of heterozygous and homozygous loss for urothelial carcinoma | 期刊论文 | Xiaopeng Mao;Baimou Li;Ying Liang;Shuhua Li;Jianwen Zhou;Qiong He;Neng Jiang;Yangshan Chen;Yu Sun;Yongmei Cui;Wenting Jiang;Han Wang;Liantang Wang;Zunfu Ke |
| 11 | 脂多糖诱导THP-1细胞固有免疫相关miRNAs表达的研究 | 期刊论文 | 余婷;邹学农;罗嘉全;黄胜;李亮平;高蔓蔓;龚铭;周治宇;陈孝 |
| 12 | In Vivo Magnetic Resonance Imaging Evaluation of Porous Tantalum Interbody Fusion Devices in a Porcine Spinal Arthrodesis Model | 期刊论文 | Zhou Zhiyu;Wei Fuxin;Huang Sheng;Gao Manman;Li Haisheng;Stodkilde Jorgensen Hans;Lind Martin;Bunger Cody;Zou Xuenong |
| 13 | Dnmt3a-Mediated DNA Methylation Changes Regulate Osteogenic Differentiation of hMSCs Cultivated in the 3D Scaffolds under Oxidative Stress | 期刊论文 | liangping li;Zemin Ling;Wenwu Dong;Xiaoying Chen;Corina Vater;Hongxing Liao;Qihua Qi;Hao Hu;Yan Chen;Michael Gelinsky;Maik Stiehler;xuenong zou |
| 14 | 蛇床子素对髓核致炎神经根痛大鼠脊髓背角p38MAPK表达的影响 | 期刊论文 | 张嘉明;易增兴;林世清;王益敏;蔡哲;魏明;孙来保;邹学农 |
| 15 | Bioadaptive Nanorod Topography of Titanium Surface to Control Cell Behaviors and Osteogenic Differentiation of Preosteoblast Cells | 期刊论文 | Xu Shao;Zhou Zhiyu;Gao Manman;Zou Changye;Che Yinglin;Cody Bunger;Zou Xuenong;Zhou Lei |
| 16 | Three-dimensional spheroid culture promotes the stemness maintenance of cranial stem cells by activating PI3K/AKT and suppressing NF-κB pathways | 期刊论文 | Da He;Renxian Wang;Jianping Mao;Bin Xiao;Dafu Chen;Wei Tian |
| 17 | Tunable Mechanical, Antibacterial, and Cytocompatible Hydrogels Based on a Functionalized Dual Network of Metal Coordination Bonds and Covalent Crosslinking | 期刊论文 | Xin Yi;Jiapeng He;Xiaolan Wang;Yu Zhang;Guoxin Tan;Zhengnan Zhou;Junqi Chen;Dafu Chen;Renxian Wang;Wei Tian;Peng Yu;Lei Zhou;Chengyun Ning |
| 18 | 原位交联透明质酸水凝胶的制备及体外生物相容性研究 | 期刊论文 | 梁嘉碧;李俊;汪婷;梁雨虹;邹学农;周光前;周治宇 |
| 19 | Construction of high surface potential polypyrrole nanorods with enhanced antibacterial properties | 期刊论文 | Wenhao Zhou;Ling Lu;Dafu Chen;Zhengao Wang;Jinxia Zhai;Renxian Wang;Guoxing Tan;Jianping Mao;Peng Yu;Chengyun Ning |
| 20 | Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling | 期刊论文 | Tang Yubo;Pan Jincheng;Huang Shuai;Peng Xinsheng;Zou Xuenong;Luo Yongxiang;Ren Dong;Zhang Xin;Li Ronggang;He Peiheng;Wa Qingde |
| 21 | NanoVelcro-captured CTC number concomitant with enhanced serum levels of MMP7 and MMP9 enables accurate prediction of metastasis and poor prognosis in patients with lung adenocarcinoma | 期刊论文 | Sun Yu;Chen Yangshan;Li Shuhua;Lei Yiyan;Xu Di;Jiang Neng;Zhang Yang;Cao Jessica;Ke Zunfu |
| 22 | Polycation-functionalized gold nanoparticles with different morphologies for superior gene transfection | 期刊论文 | Peng Yan;Ranran Wang;Nana Zhao;Hong Zhao;Da-Fu Chen;Fu-Jian Xu |
| 23 | Poly(aspartic acid)-based Degradable Assemblies for Highly Efficient Gene Delivery | 期刊论文 | Jingjun Nie;Xuebo Dou;Hao Hu;Bingran Yu;DaFu Chen;Renxian Wang;Fujian Xu |
| 24 | 一种FGF23检测试剂盒及其制备方法 | 专利 | 陈柏龄;郭志程 |
| 25 | Modified Laminoplasty Preserving the Posterior Deep Extensor Insertion into C2 Improves Clinical and Radiologic Results Compared with Conventional Laminoplasty: A Meta-Analysis | 期刊论文 | Qi Qihua;Chen Yan;Ling Zemin;Hu Hao;Ma Junxuan;Guo Wei;Gao Manman;Zhou Zhiyu;Zou Xuenong |
| 26 | Ligand-functionalized degradable polyplexes formed by cationic poly(aspartic acid)-grafted chitosan-cyclodextrin conjugates | 期刊论文 | Haiqing Song;Ruiquan Li;Shun Duan;Bingran Yu;Hong Zhao;Dafu Chen;Fujian Xu |
| 27 | Nano-Hydroxyapatite Modulates Osteoblast Differentiation Through Autophagy Induction via mTOR Signaling Pathway | 期刊论文 | Renxian Wang;Hao Hu;Jianxun Guo;Qian Wang;Jingjing Cao;Honggang Wang;Guanping Li;Jianping Mao;Xuenong Zou;Dafu Chen;Wei Tian |
| 28 | Biomimetic matrix fabricated by LMP-1 gene-transduced MC3T3-E1 cells for bone regeneration | 期刊论文 | Ma Junxuan;Guo Wei;Gao Manman;Huang Baoding;Qi Qihua;Ling Zemin;Chen Yan;Hu Hao;Zhou Hailian;Yu Fei;Chen Ke;Richards Geoff;Lin Jianjing;Zhou Zhiyu;Xiao Deming;Zou Xuenong |
| 29 | 一种广谱抗菌型伤口护理膜及其制备方法 | 专利 | 石锐;耿欢;田伟;张立群 |
| 30 | Promoting in vivo early angiogenesis with sub-micrometer strontium-contained bioactive microspheres through modulating macrophage phenotypes | 期刊论文 | Fujian Zhao;Bo Lei;Xian Li;Yunfei Mo;Renxian Wang;Dafu Chen;Xiaofeng Chen |
| 31 | Bone mesenchymal stem cells co-expressing VEGF and BMP-6 genes to combat avascular necrosis of the femoral head | 期刊论文 | Liao Hongxing;Zhong Zhixiong;Liu Zhanliang;Li Liangping;Ling Zemin;Zou Xuenong |
| 32 | 氧化应激活化RAW264.7巨噬细胞对MC3T3-E1成骨细胞迁移、增殖及成骨基因表达影响的实验研究 | 期刊论文 | 彭建强;易志新;武明鑫;黄爱军;林昆;靳松;李亮平;黄胜;罗嘉全;邹学农 |
| 33 | FOXO1-suppressed miR-424 regulates the proliferation and osteogenic differentiation of MSCs by targeting FGF2 under oxidative stress | 期刊论文 | Li Liangping;Qi Qihua;Luo Jiaquan;Huang Sheng;Ling Zemin;Gao Manman;Zhou Zhiyu;Stiehler Maik;Zou Xuenong |
| 34 | Self-Adaptive Antibacterial Porous Implants with Sustainable Responses for Infected Bone Defect Therapy | 期刊论文 | Xin Jin;Yanhua Xiong;Xinyang Zhang;Renxian Wang;Yonggang Xing;Shun Duan;Dafu Chen;Wei Tian;Fu‐Jian Xu |
| 35 | Fabrication and evaluation of a homogeneous electrospun PCL-gelatin hybrid membrane as an anti-adhesion barrier for craniectomy | 期刊论文 | Rui Shi;Jiajia Xue;Hanbin Wang;Renxian Wang;Min Gong;Dafu Chen;Liqun Zhang;Wei Tian |
| 36 | Comparison of Posterior Lumbar Interbody Fusion Versus Posterolateral Fusion for the Treatment of Isthmic Spondylolisthesis | 期刊论文 | Luo Jiaquan;Cao Kai;Yu Ting;Li Liangping;Huang Sheng;Gong Ming;Cao Cong;Zou Xuenong |
| 37 | Comparison of the risk of infections in different anti-TNF agents: a meta-analysis | 期刊论文 | Liao Hongxing;Zhong Zhixiong;Liu Zhanliang;Zou Xuenong |
| 38 | Self-assemble peptide biomaterials and their biomedical applications | 期刊论文 | Jun Chen;xuenong zou |
| 39 | COX2 is involved in hypoxia-induced TNF-alpha expression in osteoblast | 期刊论文 | Yonggang Xing;Renxian Wang;Dafu Chen;Jianping Mao;Rui Shi;Zhihong Wu;Jun Kang;Wei Tian;Chi Zhang |
| 40 | Ginkgolide B enhances the differentiation of preosteoblastic MC3T3-E1 cells through VEGF: Involvement of the p38 MAPK signaling pathway | 期刊论文 | Luo Jiaquan;Zhong Yu;Huang Sheng;Li Liangping;Zhang Chi;Zou Xuenong |
| 41 | 脊髓背角胶质细胞及p38 MAPK参与介导髓核致炎大鼠神经根痛 | 期刊论文 | 王益敏;易增兴;林世清;张嘉明;蔡哲;贺秋兰;魏明;孙来保;邹学农 |
| 42 | 经皮椎体成形术和经皮椎体后凸成型术治疗脊柱转移癌的疗效观察 | 期刊论文 | 林昆;易志新;黄爱军;靳松;邹学农 |
| 43 | 一种用于细胞培养瓶加液装置 | 专利 | 赵兴山;陈大福;郑梅;陈游洲;王任先;王芊;陈洪群;田伟 |
| 44 | 低氧诱导因子1α及2α在人BMSCs成软骨分化中的表达规律 | 期刊论文 | 龚铭;黄胜;罗嘉全;黄保丁;周治宇;代学俊;高蔓蔓;李亮平;邹学农 |
| 45 | 巯基化透明质酸的制备方法及其应用 | 专利 | 邹学农;梁嘉碧;周治宇;高蔓蔓;钟郁 |
| 46 | 一种带刻度可消毒小动物取材实验垫板 | 专利 | 王任先;陈大福 |
| 47 | Biosynthesis of Bioadaptive Materials: A Review on Developing Materials Available for Tissue Adaptation | 期刊论文 | Ma Junxuan;Zhou Zhiyu;Gao Manman;Yu Binsheng;Xiao Deming;Zou Xuenong;Bunger Cody |
| 48 | 小鼠间质干细胞在基质凝胶与细胞微球中的成软骨分化 | 期刊论文 | 龚铭;罗新乐;张昊;陈少初;胡亚威;周建华;张望;邹学农 |
| 49 | Development and Validation of a Novel Signature to Predict Overall Survival in "Driver Gene-negative" Lung Adenocarcinoma (LUAD): Results of a Multicenter Study | 期刊论文 | Yongmei Cui;Wenfeng Fang;Chaofeng Li;Kejing Tang;Jian Zhang;Yiyan Lei;Weiling He;Sui Peng;Ming Kuang;Hui Zhang;Lili Chen;Di Xu;Cuilan Tang;Wenhui Zhang;Yuxin Zhu;Wenting Jiang;Neng Jiang;Yu Sun;Yangshan Chen;Han Wang;Yingrong Lai;Shuhua Li;Qiong He;Jianwen Zhou;Yang Zhang;Millicent Lin;Honglei Chen;Chenzhi Zhou;Chunlin Wang;Jianhong Wang;Xuenong Zou;Liantang Wang;Zunfu Ke |
| 50 | 3D Printing of Mechanically Stable Calcium-Free Alginate- Based Scaffolds with Tunable Surface Charge to Enable Cell Adhesion and Facile Biofunctionalization | 期刊论文 | Zifeng Lin;Mingming Wu;Huimin He;Qingfei Liang;Chengshen Hu;Zhiwen Zeng;Delin Cheng;Guocheng Wang;Dafu Chen;Haobo Pan;Changshun Ruan |
| 51 | TRANSCRIPTIONAL ACTIVATION OF ENPP1 BY OSTERIX IN OSTEOBLASTS AND OSTEOCYTES | 期刊论文 | Gao M M;Su Q N;Liang T Z;Ma J X;Stoddart M J;Richards R G;Zhou Z Y;Zou X N |
| 52 | Gene expression profiling: identification of gene expression in human MSC chondrogenic differentiation | 期刊论文 | Ming Gong;Tangzhao Liang;Hao Zhang;Shaochu Chen;Yawei Hu;Jianhua Zhou;Xuan Zhang;Wang Zhang;Xiaojing Geng;Xuenong Zou |
| 53 | High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients | 期刊论文 | Yangshan Chen;Yu Sun;Yongmei Cui;Yiyan Lei;Neng Jiang;Wenting Jiang;Han Wang;Lili Chen;Jiping Luo;Yanyang Chen;Kejing Tang;Chengzhi Zhou;Zunfu Ke |
| 54 | The role of a semi-automated NanoVelcro system in capturing circulating tumor cells and evaluating their prognostic value for gestational choriocarcinoma | 期刊论文 | Minzhi Hou;Yongjiang Zheng;Zhiming Ding;Shanyang He;Manman Xu;Xinlin Chen;Hui Zhang;Chao Zeng;Cong Sun;Wenting Jiang;Han Wang;Hongwei Shen;Yang Zhang;Jing Liu;Shijun Sun;Neng Jiang;Yongmei Cui;Yu Sun;Yangshan Chen;Jessica Cao;Chunlin Wang;Mengzhen Li;Yi Zhang;Jianhong Wang;Millicent Lin;Zunfu Ke |
| 55 | Development and Validation of a Novel Signature to Predict Overall Survival in "Driver Gene-negative" Lung Adenocarcinoma (LUAD): Results of a Multicenter Study | 期刊论文 | Yongmei Cui;Wenfeng Fang;Chaofeng Li;Kejing Tang;Jian Zhang;Yiyan Lei;Weiling He;Sui Peng;Ming Kuang;Hui Zhang;Lili Chen;Di Xu;Cuilan Tang;Wenhui Zhang;Yuxin Zhu;Wenting Jiang;Neng Jiang;Yu Sun;Yangshan Chen;Han Wang;Yingrong Lai;Shuhua Li;Qiong He;Jianwen Zhou;Yang Zhang;Millicent Lin;Honglei Chen;Chenzhi Zhou;Chunlin Wang;Jianhong Wang;Xuenong Zou;Liantang Wang;Zunfu Ke |
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