HMBOX1在干细胞端粒功能和多能性调控中的作用和机制研究
31371508
2013
C1201.干细胞基础研究
黄军就
面上项目
教授
中山大学
80万元
HMBOX1蛋白;干细胞;转基因小鼠;植入前胚胎;端粒
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX | 期刊论文 | Hu Yang;Shi Guang;Zhang Laichen;Li Feng;Jiang Yuanling;Jiang Shuai;Ma Wenbin;Zhao Yong;Zhou Songyang;Huang Junjiu |
| 2 | Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner | 期刊论文 | Zhang Youwei;Wu Yangxiu;Mao Pingsu;Li Feng;Han Xin;Zhang Yi;Jiang Shuai;Chen Yuxi;Huang Junjiu;Liu Dan;Zhao Yong;Ma Wenbin;Zhou Songyang |
| 3 | Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9 | 期刊论文 | Zhang Xiya;Liang Puping;Ding Chenhui;Zhang Zhen;Zhou Jianwen;Xie Xiaowei;Huang Rui;Sun Ying;Sun Hongwei;Zhang Jinran;Xu Yanwen;Zhou Songyang;Huang Junjiu |
| 4 | TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses | 期刊论文 | Meixin Chen;Qingcai Meng;Yunfei Qin;Puping Liang;Peng Tan;Lian He;Yubin Zhou;Yongjun Chen;Junjiu Huang;Rong-Fu Wang;Jun Cui |
| 5 | The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation | 期刊论文 | He Quanyuan;Kim Hyeung;Huang Rui;Lu Weisi;Tang Mengfan;Shi Fengtao;Yang Dong;Zhang Xiya;Huang Junjiu;Liu Dan;Zhou Songyang |
| 6 | 端粒结合蛋白DAXX在制备肿瘤细胞调控剂中的应用 | 专利 | 松阳洲;黄军就;唐梦帆 |
| 7 | Benzo(a)pyrene disrupts mouse preimplantation embryo development | 期刊论文 | Shaoquan Zhan;Xiya Zhang;Shanbo Cao;Junjiu Huang |
| 8 | Actl6a Protects Embryonic Stem Cells From Differentiating Into Primitive Endoderm | 期刊论文 | Lu Weisi;Fang Lekun;Ouyang Bin;Zhang Xiya;Zhan Shaoquan;Feng Xuyang;Bai Yaofu;Han Xin;Kim Hyeung;He Quanyuan;Wan Ma;Shi Feng-Tao;Feng Xin-Hua;Liu Dan;Huang Junjiu;Zhou Songyang |
| 9 | CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo. | 期刊论文 | Minyan Li;Rui Huang;Xue Jiang;Yuxi Chen;Zhen Zhang;Xiya Zhang;Puping Liang;Shaoquan Zhan;Shanbo Cao;Zhou Songyang;Junjiu Huang |
| 10 | TPP1 as a versatile player at the ends of chromosomes | 期刊论文 | Sijie Zhang;Zhenhua Luo;Guang Shi;Dan Liu;Zhou Songyang;Junjiu Huang |
| 11 | Testis-specific Lypd9 is dispensable for spermatogenesis in mouse | 期刊论文 | Feng Junyan;Liang Puping;Chen Yuxi;Zhang Xiya;Songyang Zhou;Zheng Haiyan;Cao Shanbo;Huang Junjiu |
| 12 | Effective gene editing by high-fidelity base editor 2 in mouse zygotes | 期刊论文 | Liang Puping;Sun Hongwei;Ying Sun;Zhang Xiya;Xie Xiaowei;Zhang Jinran;Zhen Zhang;Chen Yuxi;Ding Chenhui;Xiong Yuanyan;Ma Wenbin;Dan Liu;Huang Junjiu;Zhou Songyang |
| 13 | Developmental history and application of CRISPR in human disease | 期刊论文 | Liang Puping;Zhang Xiya;Chen Yuxi;Huang Junjiu |
| 14 | Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility | 期刊论文 | Chen Yuxi;Liang Puping;Huang Yan;Li Minyan;Zhang Xiya;Ding Chenhui;Feng Junyan;Zhang Zhen;Zhang Xueqing;Gao Yuanzhu;Zhang Qinfeng;Cao Shanbo;Zheng Haiyan;Liu Dan;Zhou Songyang;Huang Junjiu |
| 15 | Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression | 期刊论文 | Luo Zhenhua;Feng Xuyang;Wang Haoli;Xu Weiyi;Zhao Yong;Ma Wenbin;Jiang Songshan;Liu Dan;Huang Junjiu;Zhou Songyang |
| 16 | Assessing Telomerase Activities in Mammalian Cells Using the Quantitative PCR-Based Telomeric Repeat Amplification Protocol (qTRAP) | 期刊论文 | Jiang Shuai;Tang Mengfan;Xin Huawei;Huang Junjiu |
| 17 | CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes | 期刊论文 | Liang Puping;Xu Yanwen;Zhang Xiya;Ding Chenhui;Huang Rui;Zhang Zhen;Lv Jie;Xie Xiaowei;Chen Yuxi;Li Yujing;Sun Ying;Bai Yaofu;Songyang Zhou;Ma Wenbin;Zhou Canquan;Huang Junjiu |
| 18 | Telomere regulation in pluripotent stem cells | 期刊论文 | Huang Yan;Liang Puping;Liu Dan;Huang Junjiu;Songyang Zhou |
| 19 | 小鼠精原干细胞特异性抗原4933427D06RIK抗体制备及应用 | 专利 | 黄军就;松阳洲;林卓桁 |
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