印记snoRNA基因的起源与进化及其新功能研究

30830066
2008
C0602.基因表达及非编码序列调控
屈良鹄
重点项目
教授
中山大学
175万元
非编码RNA基因;snoRNA;哺乳动物;分子进化;基因组印记
2009-01-01到2012-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The computational Rnomics platform ncRNAs and comparative transcriptomes in eukaryotes 会议论文 郑凌伶|屈良鹄*|
2 Non-coding RNAs and the acquisition of genomic imprinting in mammals 期刊论文 张意军|屈良鹄|
3 非编码基因生物学——从生命起源到转化医学 会议论文 屈良鹄|
4 非编码RNA研究—机遇与挑战 上海中科院生化与细胞研究所 会议论文 屈良鹄|
5 Drastic expression change of transposon-derived piRNAs and microRNAs in early stages of chicken embryos implies for a role in gastrulation 期刊论文 Peng Shao, Jian-You Liao, Dao-Gang Guan, Jian-Hua|Peng Shao, Jian-You Liao, Dao-Gang Guan, Jian-Hua|
6 Systematical identification of cis-elements orchestrating the expressions of miRNAs in humans 会议论文 Zhen-Dong Xiao,Li-Ting Diao, Jian-Hua Yang, Mian-B|Zhen-Dong Xiao,Li-Ting Diao, Jian-Hua Yang, Mian-B|
7 Genome-wide analysis of small RNAs and discovery of novel microRNAs in rice embryogenic calli using deep sequencing 期刊论文 Chong-Jian Chen, Qing liu, Yu-Chan Zhang, Liang-Hu|Chong-Jian Chen, Qing liu, Yu-Chan Zhang, Liang-Hu|
8 Is Increasing the Copy Number of the MicroRNA Precursor in a Vector Really Helpful for Further Improving the Level of Mature MicroRNA in Stable Cells? Reply 期刊论文 Xu, Hui|Qu, Liang-Hu|
9 mir-Explorer,基于基因组和转录组数据发掘动、植物microRNA的组合算法及分析平台 会议论文 屈良鹄|
10 ChIPBase:decoding transcriptional regulation of long non-coding RNA and microRNA gene from ChIP-Seq data 会议论文 Jian-Hua Yang,Liang-Hu Qu*|Jian-Hua Yang,Liang-Hu Qu*|
11 High-throughput analysis of small RNAs reveals the existence and dramatic changes of ncRNAs during different Trypanosoma brucei developmentally regulation stages 会议论文 L-L Zheng|Y-Z Wen|L-H Qu|Z-R Lun|
12 High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells 期刊论文 Du, Bin|Ma, Li-Ming|Huang, Mian-Bo|Zhou, Hui|Huang, Hui-Lin|Shao, Peng|Chen, Yue-Qin|Qu, Liang-Hu|
13 snoGalaxy: an integrated platform for diverse families of snoRNAs in vertebrates 会议论文 J-H Yang|Y-J Zhang|P Shao|D-G Guan|H Zhou|Y-Q Chen|L-H Qu|
14 Identification of Nematostella vectensis ncRNA from next-generation sequencing data and evolutionary implications 会议论文 J-H Li|J-H Yang|L-H Qu|
15 Extremely Low Genetic Diversity Indicating the Endangered Status of Ranodon sibiricus (Amphibia: Caudata) and Implications for Phylogeography 期刊论文 Chen, Shao-Yu|Zhang, Yi-Jun|Wang, Xiu-Ling|Sun, Jian-Yun|Xue, Yan|Zhang, Peng|Zhou, Hui|Qu, Liang-Hu|
16 Detecting microRNAs from genome and next generation sequencing data using the adaboost method with transition probability matrix and combined features 期刊论文 Guan, Dao-Gang|Liao, Jian-You|Qu, Zhen-Hua|Zhang, Ying|Qu, Liang-Hu|
17 Computational RNomics: structure identification and functional prediction of non-coding RNAs in silico 期刊论文 郑凌伶|屈良鹄|
18 Genome-wide discovery of microRNAs in eukaryotes without completed genime data using supercomputer 会议论文 Jun-Zhi WEN,Jian-You Liao,Jian-Hua YANG,Dao-Gang G|Jun-Zhi WEN,Jian-You Liao,Jian-Hua YANG,Dao-Gang G|
19 RTL-P: a sensitive approach for detecting sites of 2’-O-methylation in RNA molecules 期刊论文 Z-W Dong, P Shao, C-H Yu, L-T Diao, H Zhou, L-H Qu|Z-W Dong, P Shao, C-H Yu, L-T Diao, H Zhou, L-H Qu|
20 A novel translation inhibitory element in the 5’UTR of cyclin D3 会议论文 翁桁游|黄慧琳|赵盼盼|周蕙|屈良鹄*|
21 Insulin-Like Growth Factor-1 Receptor Is Regulated by microRNA-133 during Skeletal Myogenesis 期刊论文 Huang, Mian-Bo|Xu, Hui|Xie, Shu-Juan|Zhou, Hui|Qu, Liang-Hu|
22 Triggering Fbw7-Mediated Proteasomal Degradation of c-Myc by Oridonin Induces Cell Growth Inhibition and Apoptosis 期刊论文 Huang, Hui-Lin|Weng, Heng-You|Wang, Lu-Qin|Yu, Chun-Hong|Huang, Qiao-Juan|Zhao, Pan-Pan|Wen, Jun-Zhi|Zhou, Hui|Qu, Liang-Hu|
23 The small RNA transcriptome study of Giardia lamblia cell differentiation 会议论文 Jian-You Liao, Yan-Hua Guo, Yan Li, Wang Li, Hui Z|Jian-You Liao, Yan-Hua Guo, Yan Li, Wang Li, Hui Z|
24 Deep sequencing of small RNA transcriptome of Giardia lamblia reveals extensive tRNA cleavage during encystation 会议论文 Yanhua Guo, Jianyou Liao, Lianghu Qu*|Yanhua Guo, Jianyou Liao, Lianghu Qu*|
25 Discovery of microRNA and long non-coding RNA regulatory networks by integrating multidimensional high-throughput data 会议论文 Jian-Hua Yang, Liang-Hu Qu*|Jian-Hua Yang, Liang-Hu Qu*|
26 计算RNA组学分析平台在真核生物非编码RNA及比较转录组学研究中的应用 会议论文 郑凌伶|屈良鹄*|
27 Characterization of a cis-element regulating the snoRNA expression in Schizosaccharomyces pombe 会议论文 Li-Ting Diao,Xiao-Min Leng,Zhen-Dong Xiao,Liang-Hu|Li-Ting Diao,Xiao-Min Leng,Zhen-Dong Xiao,Liang-Hu|
28 Translational repression of cyclin D3 by a stable G-quadruplex in its 5 ' UTR Implications for cell cycle regulation 期刊论文 Weng, Heng-You|Huang, Hui-Lin|Zhao, Pan-Pan|Zhou, Hui|Qu, Liang-Hu|
29 Discovering avian snoRNAs by comparative genome and deep sequencing analysis 会议论文 P Shao|J-H Yang|H Zhou|L-H Qu|
30 Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs 期刊论文 Shao, Peng|Yang, Jian-Hua|Zhou, Hui|Guan, Dao-Gang|Qu, Liang-Hu|
31 基于半定量RT-PCR 检测2’-O-核糖甲基化修饰的方法 会议论文 董志威, 刁丽婷, 冷小敏, 王鲁勤, 余春红|
32 Liver-Enriched Transcription Factors Regulate MicroRNA-122 That Targets CUTL1 During Liver Development 期刊论文 Xu, Hui|He, Jie-Hua|Xiao, Zhen-Dong|Zhang, Qian-Qian|Chen, Yue-Qin|Zhou, Hui|Qu, Liang-Hu|
33 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps during liver development 会议论文 Hui Xu,Yin Zhang,Shu-Juan Xie,Hui Zhou,Liang-Hu Qu|Hui Xu,Yin Zhang,Shu-Juan Xie,Hui Zhou,Liang-Hu Qu|
34 ncRNAimprint database: the first step of our studies on imprinted noncoding RNAs 会议论文 Y Zhang|L-H Qu|
35 ncRNAimprint: A comprehensive database of mammalian imprinted noncoding RNAs 期刊论文 Zhang, Ying|Guan, Dao-Gang|Yang, Jian-Hua|Shao, Peng|Zhou, Hui|Qu, Liang-Hu|
36 Deep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3 ' Trailers 期刊论文 Liao, Jian-You|Ma, Li-Ming|Guo, Yan-Hua|Zhang, Yu-Chan|Zhou, Hui|Shao, Peng|Chen, Yue-Qin|Qu, Liang-Hu|
37 MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells 期刊论文 Yao, Qing|Xu, Hui|Zhang, Qian-Qian|Zhou, Hui|Qu, Liang-Hu|
38 Identification and Prevention of the Cladosporium sphaerospermum Prevalent in South China Caused by the Climatic Change 会议论文 QU Ben|ZHOU Hui*|QU Ben|ZHOU Hui*|
39 MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion 期刊论文 Zhang, Qian-Qian|Xu, Hui|Huang, Mian-Bo|Ma, Li-Ming|Huang, Qiao-Juan|Yao, Qing|Zhou, Hui|Qu, Liang-Hu|
40 deepBase: a database for deeply annotating and mining deep sequencing data 期刊论文 Yang, Jian-Hua|Shao, Peng|Zhou, Hui|Chen, Yue-Qin|Qu, Liang-Hu|
41 Genome-wide annotation of large intergenic noncoding RNAs in Gallus gallus 会议论文 Jun-Hao Li, Jian-Hua Yang, Liang-Hu Qu*|Jun-Hao Li, Jian-Hua Yang, Liang-Hu Qu*|
42 Plant noncoding RNA gene discovery by "single-genome comparative genomics" 期刊论文 Chen, Chong-Jian|Zhou, Hui|Chen, Yue-Qin|Qu, Liang-Hu|Gautheret, Daniel|
43 Deep sequencing of human nuclear and cytoplasmic small RNAs indicates most human microRNAs are imported into the nucleus 会议论文 J-Y Liao|L-M Ma|Y-H Guo|Y-C Zhang|H Zhou|P Shao|Y-Q Chen|L-H Qu|
44 SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights 期刊论文 Liu, Na|Zhou, Hui|Xiao, Zhen-Dong|Yu, Chun-Hong|Shao, Peng|Liang, Yin-Tong|Guan, Dao-Gang|Yang, Jian-Hua|Chen, Chun-Long|Qu, Liang-Hu|
45 动物snmRNA的系统识别与鉴定 期刊论文 邵鹏|屈良鹄|
46 MicroRNAs involved in TGF-β1-induced EMT and the development of renal fibrosis 会议论文 Ma Liming, Qu Lianghu*|Ma Liming, Qu Lianghu*|
47 The New Frontier in the post-genomic era 期刊论文 屈良鹄|
48 Deciphering the transcriptional regulation of intergenic microRNAs in humans with ACTLocater 期刊论文 Z-D Xiao|L-T Diao|J-H Yang|H Xu|M-B Huang|Y-J Deng|H Zhou|L-H Qu|
49 Genome-wide evolutionary analysis of the noncoding RNA genes and noncoding DNA of Paramecium tetraurelia 期刊论文 Chen, Chun-Long|Zhou, Hui|Liao, Jian-You|Qu, Liang-Hu|Amar, Laurence|
50 Systematic discovery of small non-coding RNAs and their target genes using next-generation sequencing data 会议论文 J-H Yang|L-H Qu|
51 A systematic screen and analysis of imprinted snoRNA genes in mammalian genomes 会议论文 J-H Yang|H Zhou|J-Y Chen|Y-J Zhang|L-H Qu|
52 snmRNA的系统识别与鉴定(大会报告) 会议论文 屈良鹄|
53 starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data 期刊论文 Yang, Jian-Hua|Li, Jun-Hao|Shao, Peng|Zhou, Hui|Chen, Yue-Qin|Qu, Liang-Hu|
54 Oridonin promotes Fbw-7 mediated turnover of c-Myc: targeting oncogene addiction 会议论文 黄慧琳|翁桁游|周蕙|屈良鹄*|
55 Diversity endogenous small non-coding RNAs in chicken embryos during early development 会议论文 Shao Peng|Shao Peng|
56 Extensive analysis of two major classes of snoRNAs in the filamentous fungus Neurospora crassa: the structural, functional and evolutionary insights 会议论文 N Liu|C-H Yu|Z-D Xiao|Y-T Liang|D-Gang Guan|J-H Yang|L-H Qu|H Zhou|
57 微RNA功能研究的几个重要平台和思路 会议论文 屈良鹄|
58 beta-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/beta-catenin-signaling pathway 期刊论文 Zhou, A-D|Diao, L-T|Xu, H.|Xiao, Z-D|Li, J-H|Zhou, H.|Qu, L-H|
59 The promoter of rpl26 is required for the snR49 transcription in Schizosaccharomyces pombe 会议论文 Xiao-Min Leng, Li-Ting Diao, Yan-Hua Guo, Bin Li,|Hui Zhou*|Xiao-Min Leng, Li-Ting Diao, Yan-Hua Guo, Bin Li,|Hui Zhou*|
60 tRNA 3’trailers are a novel class of functional ncRNAs that may be related to cell proliferation, stemness maintaining and stress regulation 会议论文 Lu-Qin Wang, Jian-You Liao, Chun-Hong Yu,Liang-Hu|Lu-Qin Wang, Jian-You Liao, Chun-Hong Yu,Liang-Hu|
61 The hiding targets: A group of beyond-predicted microRNAs contribute to silencing of CUTL1 in different tissues during mouse development 会议论文 Jie-Hua He, Hui Xu, Shu-juan Xie, Yin Zhang, Hui Z|Liang-Hu Qu *|Jie-Hua He, Hui Xu, Shu-juan Xie, Yin Zhang, Hui Z|Liang-Hu Qu *|
62 Plant noncoding RNA gene discovery by "single-genome comparative genomics" 期刊论文 Chen, Chong-Jian|Zhou, Hui|Chen, Yue-Qin|Qu, Liang-Hu|Gautheret, Daniel|
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