表观基因组关联分析新型细胞类型去卷积算法研究
31771464
2017
C0608.生物数据资源与分析方法
Andrew Teschendorff
面上项目
研究员
中国科学院上海营养与健康研究所
56万元
癌症;统计遗传学;系统生物学;表观遗传学;人
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Quantifying Waddington's epigenetic landscape: a comparison of single-cell potency measures | 期刊论文 | Shi Jifan;Teschendorff Andrew E.;Chen Weiyan;Chen Luonan;Li Tiejun |
| 2 | EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data | 期刊论文 | Teschendorff Andrew E.;Zhu Tianyu;Breeze Charles E.;Beck Stephan |
| 3 | Ultra-fast scalable estimation of single-cell differentiation potency from scRNA-Seq data | 期刊论文 | Andrew E Teschendorff;Alok K Maity;Xue Hu;Chen Weiyan;Matthias Lechner |
| 4 | Improved detection of tumor suppressor events in single-cell RNA-Seq data | 期刊论文 | Andrew E. Teschendorff;Ning Wang |
| 5 | Cell and tissue type independent age-associated DNA methylation changes are not rare but common. | 期刊论文 | Zhu Tianyu;Zheng Shijie C;Paul Dirk S;Horvath Steve;Teschendorff Andrew E |
| 6 | A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes | 期刊论文 | Chenglong You;Sijie Wu;Shijie C. Zheng;Tianyu Zhu;Han Jing;Ken Flagg;Guangyu Wang;Li Jin;Sijia Wang;Andrew E. Teschendorff |
| 7 | A comparison of epigenetic mitotic-like clocks for cancer risk prediction | 期刊论文 | Teschendorff; Andrew E. |
| 8 | Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome | 期刊论文 | Chen W;Morabito SJ;Kessenbrock K;Enver T;Meyer KB;Teschendorff AE |
| 9 | Identification of differentially methylated cell types in epigenome-wide association studies. | 期刊论文 | Zheng Shijie C;Breeze Charles E;Beck Stephan;Teschendorff Andrew E |
| 10 | DNA methylation aging clocks: challenges and recommendations | 期刊论文 | Bell CG;Lowe R;Adams PD;Baccarelli AA;Beck S;Bell JT;Christensen BC;Gladyshev VN;Heijmans BT;Horvath S;Ideker T;Issa JJ;Kelsey KT;Marioni RE;Reik W;Relton CL;Schalkwyk LC;Teschendorff AE;Wagner W;Zhang K;Rakyan VK |
| 11 | EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI | 期刊论文 | Zheng Shijie C.;Breeze Charles E.;Beck Stephan;Dong Danyue;Zhu Tianyu;Ma Liangxiao;Ye Wei;Zhang Guoqing;Teschendorff Andrew E. |
| 12 | ebGSEA: an improved Gene Set Enrichment Analysis method for Epigenome-Wide-Association Studies | 期刊论文 | Dong Danyue;Tian Yuan;Zheng Shijie C.;Teschendorff Andrew E. |
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