环形RNA计算系统生物学研究
31730111
2017
C0602.基因表达及非编码序列调控
杨力
重点项目
研究员
复旦大学
298万元
计算生物学;非编码RNA;环形RNA;转录组;RNA二级结构
2018-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription | 期刊论文 | Man Wu;Guang Xu;Chong Han;Peng-Fei Luan;Yu-Hang Xing;Fang Nan;Liang-Zhong Yang;Youkui Huang;Zheng-Hu Yang;Lin Shan;Li Yang;Jiaquan Liu;Ling-Ling Chen |
| 2 | 计算生物学分析在基因组编辑研究中的应用 | 期刊论文 | 王 滢;熊义春;陈 佳;杨 力 |
| 3 | 系统性红斑狼疮环形RNA标记物及检测试剂 | 专利 | 陈玲玲;杨力;沈南;刘楚霄;李响;姜珊;南芳;崔燕鸽 |
| 4 | 融合深度学习模型的单细胞转录组计算分析方法和系统 | 专利 | 杨力;李国卫;南芳;袁国华 |
| 5 | Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells | 期刊论文 | Chun-Jie Guo;Xu-Kai Ma;Yu-Hang Xing;Chuan-Chuan Zheng;Yi-Feng Xu;Lin Shan;Jun Zhang;Shaohua Wang;Yangming Wang;Gordon G. Carmichael;Li Yang;Ling-Ling Chen |
| 6 | SCAPTURE: a deep learning-embedded pipeline that captures polyadenylation information from 3' tag-based RNA-seq of single cells | 期刊论文 | Guo-Wei Li;Fang Nan;Guo-Hua Yuan;Chu-Xiao Liu;Xindong Liu;Ling-Ling Chen;Bin Tian;Li Yang |
| 7 | Linking circular intronic RNA degradation and function in transcription by RNase H1 | 期刊论文 | Xiang Li;Jia-Lin Zhang;Yun-Ni Lei;Xiao-Qi Liu;Wei Xue;Yang Zhang;Fan Nan;Xiang Gao;Jun Zhang;Jia Wei;Li Yang;Ling-Ling Chen |
| 8 | Base editing with a cpf1-cytidine deaminase fusion | 期刊论文 | Xiaosa Li;Ying Wang;Yajing Liu;Bei Yang;Xiao Wang;Jia Wei;Zongyang Lu;Yuxi Zhang;Jing Wu;Xingxu Huang;Li Yang;Jia Chen |
| 9 | CIRCexplorer pipelines for circRNA annotation and quantification from non-polyadenylated RNA-seq datasets | 期刊论文 | Xu-Kai Ma;Wei Xue;Ling-Ling Chen;Li Yang |
| 10 | N6-Methyladenosines Modulate A-to-I RNA Editing | 期刊论文 | Jian-Feng Xiang;Qin Yang;Chu-Xiao Liu;Man Wu;Ling-Ling Chen;Li Yang |
| 11 | Development and Application of Base Editors | 期刊论文 | Bei Yang;Li Yang;Jia Chen |
| 12 | Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity | 期刊论文 | Chu-Xiao Liu;Xiang Li;Fang Nan;Shan Jiang;Xiang Gao;Si-Kun Guo;Wei Xue;Yange Cui;Kaige Dong;Huihua Ding;Bo Qu;Zhaocai Zhou;Nan Shen;Li Yang;Ling-Ling Chen |
| 13 | Knockout of circRNAs by base editing back-splice sites of circularized exons | 期刊论文 | Xiang Gao;Xu-Kai Ma;Xiang Li;Guo-Wei Li;Chu-Xiao Liu;Jun Zhang;Ying Wang;Jia Wei;Jia Chen;Ling-Ling Chen;Li Yang |
| 14 | Biogenesis and Regulatory Roles of Circular RNAs | 期刊论文 | Li Yang;Jeremy E. Wilusz;Ling-Ling Chen |
| 15 | Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs | 期刊论文 | Ying Wang;Runze Gao;Jing Wu;Yi-Chun Xiong;Jia Wei;Sipin Zhang;Bei Yang;Jia Chen;Li Yang |
| 16 | RNA circles with minimized immunogenicity as potent PKR inhibitors | 期刊论文 | Chu-Xiao Liu;Si-Kun Guo;Fang Nan;Yi-Feng Xu;Li Yang;Ling-Ling Chen |
| 17 | The Biogenesis, Functions, and Challenges of Circular RNAs | 期刊论文 | Xiang Li;Li Yang;Ling-Ling Chen |
| 18 | CIRCpedia v2: An Updated Database for Comprehensive Circular RNA Annotation and Expression Comparison | 期刊论文 | Rui Dong;Xu-Kai Ma;Guo-Wei Li;Li Yang |
| 19 | Screening for functional circular RNAs using the CRISPR-Cas13 system | 期刊论文 | Siqi Li;Xiang Li;Wei Xue;Lin Zhang;Liang-Zhong Yang;Shi-Meng Cao;Yun-Ni Lei;Chu-Xiao Liu;Si-Kun Guo;Lin Shan;Man Wu;Xiao Tao;Jia-Lin Zhang;Xiang Gao;Jun Zhang;Jia Wei;Jinsong Li;Li Yang;Ling-Ling Chen |
| 20 | Genome-wide screening of NEAT1 regulators reveals cross-regulation between paraspeckles and mitochondria | 期刊论文 | Yang Wang;Shi-Bin Hu;Meng-Ran Wang;Run-Wen Yao;Di Wu;Li Yang;Ling-Ling Chen |
| 21 | Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus | 期刊论文 | Run-Wen Yao;Guang Xu;Ying Wang;Lin Shan;Peng-Fei Luan;Yang Wang;Man Wu;Liang-Zhong Yang;Yu-Hang Xing;Li Yang;Ling-Ling Chen |
| 22 | 一种基因碱基编辑器 | 专利 | 陈佳;杨力;黄行许;杨贝;王潇;李佳楠 |
| 23 | Fusion proteins for improved precision in base editing | 专利 | Jia Chen;Xingxu Huang;Li Yang;Bei Yang;Xiaosa Li;Ying Wang;Yajing Liu |
| 24 | Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion | 期刊论文 | Xiao Wang;Jianan Li;Ying Wang;Bei Yang;Jia Wei;Jing Wu;Ruixuan Wang;Xingxu Huang;Jia Chen;Li Yang |
| 25 | Fast and Furious: insights of back splicing regulation during nascent RNA synthesis | 期刊论文 | Wei Xue;Xu-Kai Ma;Li Yang |
| 26 | CIRCexplorer3: A CLEAR pipeline for direct comparison of circular and linear RNA expression | 期刊论文 | Xu-Kai Ma;Meng-Ran Wang;Chu-Xiao Liu;Rui Dong;Gordon G. Carmichael;Ling-Ling Chen;Li Yang |
| 27 | Altered processing of lncRNAs in stem cells contributes to non-conserved functions | 期刊论文 | 马旭凯;郭纯洁;杨 力;陈玲玲 |
| 28 | 一种基因碱基编辑器 | 专利 | 陈佳;杨力;黄行许;杨贝;王潇;李佳楠 |
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