核受体RARβ调控肝脏脂质沉积和胰岛素抵抗的机制研究
31671224
2016
C1107.营养与代谢生理学
李于
面上项目
研究员
中国科学院上海营养与健康研究所
65万元
脂质代谢;2型糖尿病;脂肪肝;胰岛素抵抗;高血糖
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | CREBZF在治疗、预防和诊断代谢性疾病中的应用(PCT国际申请号:PCT/CN2017/087688,国际申请日:09.06.2017) | 专利 | 李于;张菲菲;胡志敏 |
| 2 | 玫瑰茄-绿茶组合物在改善饮食诱导的代谢紊乱中的应用 | 专利 | 李于;韩亚美;刘正帅;薛天一 |
| 3 | 成纤维细胞生长因子21的前世今生:胰岛素增敏机制与临床研究 | 期刊论文 | 崔奥媛;李于 |
| 4 | Optimized analysis of In vivo and in vitro hepatic steatosis | 期刊论文 | Cui Aoyuan;Hu Zhimin;Han Yamei;Yang Yi;Li Yu |
| 5 | Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats | 期刊论文 | Zhao ZH;Xin FZ;Xue Y;Hu Z;Han Y;Ma F;Zhou D;Liu XL;Cui A;Liu Z;Liu Y;Gao J;Pan Q;Li Y;Fan JG |
| 6 | Hepatic CREBZF couples insulin to lipogenesis by inhibiting Insig activity and contributes to hepatic steatosis in diet-induced insulin-resistant mice | 期刊论文 | Zhang Feifei;Hu Zhimin;Li Gaopeng;Huo Shaofeng;Ma Fengguang;Cui Aoyuan;Xue Yaqian;Han Yamei;Gong Qi;Gao Jing;Bian Hua;Meng Zhuoxian;Wu Haifu;Long Gang;Tan Yi;Zhang Yan;Lin Xu;Gao Xin;Xu Aimin;Li Yu |
| 7 | Berberine attenuates hepatic steatosis and enhances energy expenditure in mice by inducing autophagy and fibroblast growth factor 21 | 期刊论文 | Sun Yixuan;Xia Mingfeng;Yan Hongmei;Han Yamei;Zhang Feifei;Hu Zhimin;Cui Aoyuan;Ma Fengguang;Liu Zhengshuai;Gong Qi;Chen Xuqing;Gao Jing;Bian Hua;Tan Yi;Li Yu;Gao Xin |
| 8 | The ER-localized Ca2+-binding protein calreticulin couples ER stress to autophagy by associating | 期刊论文 | Yang Yunzhi;Ma Fengguang;Liu Zhengshuai;Su Qian;Liu Yuxiao;Liu Zhixue;Li Yu |
| 9 | Post-translational regulation of lipogenesis via AMPK phosphorylation of insulin-induced gene | 期刊论文 | Han Yamei;Hu Zhimin;Cui Aoyuan;Liu Zhengshuai;Ma Fengguang;Xue Yaqian;Liu Yuxiao;Zhang Feifei;Zhao Zehua;Yu Yanyan;Gao Jing;Wei Chun;Li Jingya;Fang Jing;Li Jia;Fan Jian-Gao;Song Bao-Liang;Li Yu |
| 10 | CREBZF as a key Regulator of STAT3 Pathway in the Control of Liver Regeneration in Mice | 期刊论文 | Hu Zhimin;Han Yamei;Liu Yuxiao;Zhao Zehua;Ma Fengguang;Cui Aoyuan;Zhang Feifei;Liu Zhengshuai;Xue Yaqian;Bai Jinyun;Wu Haifu;Bian Hua;Chin Y. Eugene;Yu Ying;Meng Zhuoxian;Wang Hua;Liu Yong;Fan Jiangao;Gao Xin;Chen Yan;Li Yu |
| 11 | CREBZF在治疗、预防和诊断代谢性疾病中的应用(中国专利申请号:CN201710423436.5, 申请日2017.06.07) | 专利 | 李于;张菲菲;胡志敏 |
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